30results about How to "Avoid toxic side effects" patented technology

The invention discloses the application of curcumin in preparing a medicine for treating the intestinal ischemia reperfusion injury in the technical field of medicine preparation. According to the application of the curcumin in preparing the medicine for treating the intestinal ischemia reperfusion injury, an intestinal ischemia reperfusion injury model is prepared, and curcumin-polyvinylpyrrolidone (PVP) solid dispersions are used for treating the intestinal ischemia reperfusion injury model after being dissolved by normal saline for injection. The therapeutic effect of the curcumin is detected through gross tissue observation, disease model death rate, histopathological changes, serum liver and renal function changes and changes of apoptosis and inflammation-related regulatory factors in tissues. According to results, the intestinal ischemia reperfusion injury can be effectively treated by the curcumin, and a basis is provided for the application of the curcumin in emergency and critical symptoms.

The invention provides a making method of capelin caviar. The caviar consists of the following components of roe, spice fluid, condiments, copper gluconate and a preservative. The caviar is made through the following steps of performing pretreatment: performing salt treatment on fresh roe; performing extraction so as to obtain the spice fluid: taking the following components in parts by weight of purple perilla, fresh ginger, hot peppers, cinnamon bark, cloves, garlic, amomum cardamomum, star aniseeds, fructus tsaoko and Chinese prickly ash, performing decoction for 2-4 times, performing filtration, combining filtrate so as to obtain the spice fluid; performing preparation: taking the roe after the salt treatment and the spice fluid, in parts by weight, performing steaming, performing filtration, performing screening to obtain average-grain roe, taking the average-grain roe, the condiments and the copper gluconate in parts by weight, performing steaming, adding a preservative, and performing uniform mixing so as to obtain the caviar; and performing preservation: placing the caviar in the shade, performing packaging, performing sterilization, performing warehousing, and performing preservation. According to the caviar prepared by the making method disclosed by the invention, high nutrient value of the roe is reserved, the fishy taste and foreign taste are removed, the fresh-keeping time of the caviar is prolonged, the caviar is prevented from being deteriorated in a short time, and the mouth feel and the nutrient value of the caviar are not influenced.

The invention discloses a plaster with a joint injury and acupoint repair effect. The plaster is prepared from, by weight, 35-65 parts of radix dipsaci, 30-57 parts of herba cistanches, 30-55 parts ofroots of sambucus williamsii hance, 20-33 parts of radix aconiti, 15-29 parts of ovateleaf knotweed rhizome, 16-35 parts of flowers of carthamus tinctorius L., 15-27 parts of caulis tinosporae sinensis, 22-38 parts of fried fructus gardeniae, 30-40 parts of frankincense, 6-17 parts of borneol, 10-22 parts of rhzizoma drynariae, 8-25 parts of resina draconis, 15-25 parts of natural copper, 13-24 parts of shaved cinnamon bark and 300-750 parts of a matrix. Through the cooperation of the structures, the plaster solves the problems that by applying bandaging, local sealing, physiotherapy and anti-inflammatory and analgesic drugs, the treatment effects of the methods are poor, the recovery time is long, the drugs are limited to inflammatory prevention and analgesia and lack the functions of promoting local micro-circulation and alleviating local swelling; the plaster quickly relieve pain and swelling of acute soft tissue injuries in the acute phase and promotes function recovery.

The invention discloses a traditional Chinese medicine composition for treating pyesis and a preparation method of the traditional Chinese medicine composition, and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition is prepared from the following raw materials and pharmaceutically common auxiliary materials: astragalus membranaceus, radix angelicae, mangnolia officinalis, liquorice, poria cocos, fructus forsythia, ginseng, angelica sinensis, peony, costus roots, ligusticum wallichii, divaricate saposhnikovia roots, honeysuckle, platycodon grandiflorum, cassia twig and scutellaria baicalensis. The preparation method comprises the following steps: weighing and crushing scutellaria baicalensis for later use; respectively weighing other medicinal materials, adding water to decoct for a plurality of times, and mixing decoction solutions; filtering and concentrating into clear paste; adding ethanol for extraction, drying and crushing ethanol filtrate at a low temperature; and adding broken scutellaria baicalensis and the pharmaceutically common auxiliary materials, and mixing to prepare the medicine. According to the traditional Chinese medicine, the syndrome differentiation treatment of the traditional Chinese medicines and the principle of monarch, minister, assistant and guide, the traditional Chinese medicines are scientifically combined; an effective pharmaceutical composition is provided; and a preparation prepared by a special preparation method has a general therapeutic effect on pyesis caused by pyogenic bacteria, and is good in taste, good in effect and free of toxic or side effect.

The invention provides an externally-applied traditional Chinese medicine composition for treating gout. The externally-applied traditional Chinese medicine composition adopts the compatibility of a sovereign drug, a ministerial drug, an adjuvant drug and a conductant drug to synergistically take effect, wherein the sovereign drug is capable of promoting blood circulation to remove blood stasis, dispelling wind, relieving pains and inducing diuresis to alleviate edema, and has the effects of rapidly decreasing swelling and relieving pains on swellings caused by gout; the ministerial drug is capable of clearing away heat, removing toxicity, purging intense heat, dispersing heart heat, decreasing swelling and relieving pains, is capable of reinforcing the effect of decreasing swelling and relieving pains of the sovereign drug, and is capable of clearing away heat and removing toxicity according to accompanied symptoms of gout; through the compatibility of the sovereign drug and the ministerial drug, the effect of decreasing swelling and relieving pains is achieved, and pains of a patient are rapidly reduced; the adjuvant drug is capable of dispelling wind, eliminating dampness and activating meridians to stop pains, is an assisting drug, and is matched with the sovereign drug and the ministerial drug to reinforce the effects of dispelling wind, decreasing swelling and relieving pains; the drug effect of the guiding drug directly reaches the affected part, and permeates through the anadesma; the compatibility of all the drugs is achieved, the effects of relaxing tendons, activating collaterals, promoting channels, removing dampness, clearing away turbidness, decreasing swelling and relieving pains are jointly achieved, and local swelling pains caused by gout are rapidly relieved.

The invention discloses an anti-liver cancer health product containing isoalantolactone. The raw materials include, by weight percentage, 60-80% of isoalantolactone, 5-10% of a herba scutellariae barbatae extract, 5-10% of a fructus polygoni orientalis extract, 5-10% of a prunella vulgaris extract and 5-10% of a euphorbia helioscopia extract. The pioneering technology adopted by the invention usesisoalantolactone as the anti-liver cancer core functional raw material, puts forward the Chinese medicinal composition treating liver cancer, and through reasonable compatibility, the anti-liver cancer Chinese herbal medicine mixed health product is formed. Experimental study on human in vitro liver cancer cells finds that the isoalantolactone composition has good inhibition effect on in vitro tumor cells and good control effect on liver cancer, can avoid excessive toxic and side effects of chemical synthetic drugs on the human body, and also has wide sources, thus having good application prospects.

The invention discloses a food composition for preventing and treating deficiency of kidney yang as well as an application method thereof. The food composition at least comprises maca, kidney bean, Chinese chive seed and okra, the mass proportion sum of maca, kidney bean, Chinese chive seed and okra is 40-60%, and the raw materials are prepared to mixing powder according to a composition formula and then directly eaten, or the prepared mixing powder and an edible accessory are used for making other food forms for eating. The experiment shows that the food composition can obviously improve and recover injury of sexual gland, accessory organ and immunization organ of deficiency of kidney yang model mouse due to hydrocortisone, normal autonomous activities frequency and capability can be recovered for tested mouse, compared with a model control group, the food composition has significant difference, and the food composition has the health care effects for tonifying kidney and invigorating yang, and replenishing qi and enriching blood, and can be used for treating deficiency of kidney yang by long-term eating.

A double-view-window gradually-progressing lighting-face increasing and reducing alternating correction eye protecting device mainly comprises a light shielding device, view-windows, a view-window switching device, a circulation lighting-face motion changing mechanism and an operation system. The double-view-window gradually-progressing lighting-face increasing and reducing alternating correction eye protecting device is newly designed for overcoming the defects of myopia treatment conducted through operations, medicine and some focus-changing light-emitting instruments and health-care measures and is especially used for treating visual impairment of human beings and caring eyesight of human beings. The eye protecting device has the advantages that a pure physical method is used for treating and caring myopia, especially pseudomyopia and asthenopia, so that toxic side effects generated by medicine treatment, risks caused by operation treatment and light pollution unfavorable factors generated, on eyes, by some products which are used for treating eyes are avoided. Consequently, the device can be used for treating and caring people safely and reliably.

The invention provides a traditional Chinese medicine composition for treating bone injury diseases and a making method of the traditional Chinese medicine composition and belongs to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition for treating bone injury diseases is made of dactylicapnos roots, psammosilene tunicoides, rheum officinale, anisodusacutangulus, kusnezoff monkshood roots, radix angelicae tuhuo, asarum, nux vomica, alangium platanifolium, white mustard seeds, cissus hexangularis, shortstalk monkshood roots, sanguis draxonis, lithargite, pseudo-ginseng, musk and plant oil according to a ratio. Due to matching of dactylicapnos roots, psammosilene tunicoides, rheum officinale, anisodus acutangulus, kusnezoff monkshood roots, radix angelicae tuhuo, asarum, nux vomica, alangium platanifolium, white mustard seeds, cissus hexangularis, shortstalk monkshood roots, sanguis draxonis, lithargite, pseudo-ginseng, musk and plant oil asmaster medicines, assistant medicines and auxiliary medicines, the traditional Chinese medicine composition has effects on pain diseases such as arthritis, hyperostosis, cervical spondylosis, bone fracture, intervertebral disc protrusion, gout and rheumatism.

The invention relates to the technical field of nano drug carriers, and specifically discloses a preparation method and application of tussah silk fibroin nanoparticles. Turbid liquid, ultrasonic, centrifugal separation, freeze-drying and other operations. The present invention uses natural tussah silkworm cocoons with excellent biocompatibility as raw materials to ensure the biosafety performance of nanocarriers, and the whole preparation method is simple and quick, and tussah silk nano-particles containing RGD peptide natural targeting ligands are prepared to avoid It avoids the severe environment and the toxic and side effects caused by the residue of organic solvents in the modification process of foreign ligands, and at the same time has a good function of targeting macrophages, the particle size distribution is relatively uniform, and it has high drug loading and encapsulation. It has a good application potential in the treatment of ulcerative colitis.

The invention belongs to the field of traditional Chinese medicines and particularly relates to an oral traditional Chinese medicine composition for treating depressive disorder as well as a preparation and preparation method thereof. The oral traditional Chinese medicine composition is prepared from pharmaceutically acceptable auxiliaries, radix bupleuri, angelica, radix paeoniae alba, ramulus cinnamomi, crinum asiaticum and pleurotus citrinopileatus, wherein radix bupleuri, angelica, radix paeoniae alba, ramulus cinnamomi and pleurotus citrinopileatus are extracted by virtue of a water extraction alcohol precipitation method, and crinum asiaticum is a volatile oil component which has a relative density lower than 1.0 and is extracted by virtue of a vapor distillation method. The dose form of the oral traditional Chinese medicine composition is oral liquid. The oral traditional Chinese medicine composition has good treatment effects on depressive disorder and further has safety.

The present invention relates to use of therapeutic agents that specifically bind and inhibit TLR3 signalling in order to sensitize patients to treatment with corticosteroids, notably for the treatment and prevention of inflammatory and autoimmune disorders.

The invention relates to a traditional Chinese medicinal composition for treating gastrointestinal cancer. The composition is prepared through clinic test repeated verification, and accords with the theory of traditional Chinese medicine science. The composition adopts Raphanus sativus L, toad skin, Radix araliae armatae, persimmon frost, Kalimeris indica and Glabrous Sarcandra Herb as main medicines to realize heat clearing, detoxifying, cancer preventing and evil expelling, adopts cherry leaf, all-grass of Matsumura Leafflower, leaf of Jobstears, orange peel, dry moss and Fiveleaf Gynostemma Herb as auxiliary medicines to reinforce heat clearing, detoxifying and cancer preventing efficacies, adopts asparagus, Lobelia sessilifolia Lamb., Garcinia mangostana L., orange peel and mulberry to tonify qi, nourish stomach, warm meridian and relieve pains, and adopts apple, grape, banana, jujube, Oberonia iridifolia Lindl, Root of Delavay Schefflera, twoleaf beadruby herb and serrate gtorybower flower to nourish spleen, harmonize stomach, invigorate spleen, tonify lung and moisten intestine. The composition starts with qi tonifying, stomach nourishing and gastrointestinal mucosa damage reducing health efficacies and health, selects traditional Chinese medicines to directly kill cancer cells and block generation of newborn blood vessels to make the cancer cells cannot obtain sufficient nutrition supply, and has unique curative effects on various stomach cancer patients.