Oral Chinese medicinal composition for treating depression, preparation and preparation method thereof

A technique for depression and composition, which is applied in the field of oral Chinese medicine composition for treating depression and its preparation and preparation, and can solve problems such as lack of compound preparation products and few varieties of antidepressant Chinese medicines

Active Publication Date: 2021-04-23
杨添淞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

But at present, there are few types of antidepressant traditional Chinese medicines in my country, and there is a lack of compound preparations.

Method used

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  • Oral Chinese medicinal composition for treating depression, preparation and preparation method thereof
  • Oral Chinese medicinal composition for treating depression, preparation and preparation method thereof
  • Oral Chinese medicinal composition for treating depression, preparation and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] Embodiment 1 Chinese medicinal oral liquid for treating depression and its preparation

[0035]

[0036] Preparation:

[0037] A. Take the prescribed amount of Bupleurum bupleuri, angelica, white peony root, cassia twig, and elm yellow mushroom, respectively, crush them through a 50-mesh sieve, mix them to obtain coarse powder of medicinal materials, add water to decoct twice, and add water 7 times the weight of coarse powder of medicinal materials for the first time Decoct for 4 hours, add 3 times the weight of the crude medicinal powder for the second time and decoct for 2 hours, filter and combine the decoction, concentrate to a concentrated solution with a relative density of 1.20, let it stand for cooling, add ethanol to the concentrated solution to make the ethanol The volume percentage is 75%, stay overnight at 4°C, filter to remove insoluble matter, collect the filtrate to distill under reduced pressure to remove ethanol, obtain a refined solution, and concen...

Embodiment 2

[0041] Embodiment 2 Chinese medicine oral liquid for treating depression and its preparation

[0042]

[0043] Preparation:

[0044] A. Take the prescribed amount of Bupleurum bupleuri, angelica, white peony root, cassia twig, and elm yellow mushroom, respectively, crush them through a 50-mesh sieve, mix them to obtain coarse powder of medicinal materials, add water to decoct twice, and add water 7 times the weight of coarse powder of medicinal materials for the first time Decoct for 4 hours, add 3 times the weight of the crude medicinal powder for the second time and decoct for 2 hours, filter and combine the decoction, concentrate to a concentrated solution with a relative density of 1.20, let it stand for cooling, add ethanol to the concentrated solution to make the ethanol The volume percentage is 75%, stay overnight at 4°C, filter to remove insoluble matter, collect the filtrate to distill under reduced pressure to remove ethanol, obtain a refined solution, and concent...

Embodiment 3

[0048] Example 3 Chinese medicine oral liquid for treating depression and its preparation

[0049]

[0050] Preparation:

[0051] A. Take the prescribed amount of Bupleurum bupleuri, angelica, white peony root, cassia twig, and elm yellow mushroom, respectively, crush them through a 50-mesh sieve, mix them to obtain coarse powder of medicinal materials, add water to decoct twice, and add water 7 times the weight of coarse powder of medicinal materials for the first time Decoct for 4 hours, add 3 times the weight of the crude medicinal powder for the second time and decoct for 2 hours, filter and combine the decoction, concentrate to a concentrated solution with a relative density of 1.20, let it stand for cooling, add ethanol to the concentrated solution to make the ethanol The volume percentage is 75%, stay overnight at 4°C, filter to remove insoluble matter, collect the filtrate to distill under reduced pressure to remove ethanol, obtain a refined solution, and concentrat...

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Abstract

The invention belongs to the field of traditional Chinese medicines, and in particular relates to an oral Chinese medicine composition for treating depression, its preparation and preparation method. The oral Chinese medicine composition for treating depression is made from pharmaceutically acceptable pharmaceutical excipients and Bupleurum, Angelica, Radix Paeoniae Alba, Cinnamon Twig, Manjusri Orchid, and Yellow Mushroom, wherein Bupleurum, Angelica, Radix Paeoniae Alba, Cinnamon twigs and ulm yellow mushrooms are extracted by water extraction and alcohol precipitation, and Manjusri orchids are extracted by steam distillation to extract the volatile oil components with a relative density below 1.0. The dosage form of the oral Chinese medicine composition is preferably an oral liquid. The oral Chinese medicinal composition has good therapeutic effect and safety on depression.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to an oral Chinese medicine composition for treating depression, its preparation and a preparation method. Background technique [0002] Depression is a mood disorder syndrome. Patients mainly manifest as significant and persistent depression, low self-esteem, pessimism, loss of energy, changes in appetite, more or less sleep, and decreased concentration; lack of desire for social interaction and exploration, Severe patients even have suicidal tendencies. The etiology and pathogenesis of depression are still not fully understood. It is generally believed that depression may be the result of the interaction of physiological, psychological and social factors. The accelerated pace of life and increased work, study and social pressure may be the external environmental factors leading to depression. According to reports, the prevalence of depression in China is...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/88A61K9/08A61P25/24
CPCA61K9/0095A61K36/07A61K36/232A61K36/233A61K36/54A61K36/65A61K36/71A61K36/88A61K47/40A61K2236/331A61K2236/37A61K2300/00
Inventor 杨添淞孙维伯聂宏许骏杨燕王德龙李超然
Owner 杨添淞
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