70results about How to "Improve SOD vitality" patented technology

The invention relates to an ecological repairing method of sphagna macroalgae to an eutrophic open sea area, which is mainly characterized by comprising the following steps: selecting a cultivating area; fabricating a raft frame and a lace curtain of a cultivating facility; pulling seedlings of conchospores cultivated by a seedling net, conveying the seedling net, hanging the lace curtain and managing the dryness; managing the cultivation of ripe sphagna macroalgae in sea; picking the ripe sphagna macroalgae; and measuring nitrogen and phosphorus in texture. Sphagna can obviously reduce the danger of large-area red tide induced by excessive elements such as nitrogen, phosphorus, and the like in a neritic zone, can be used as a repair tool of water eutrophication in the neritic zone, is cultivated in the eutrophic sea area so that necessary nutrient substances can be provided and nutrient substances in sea can be transformed out of a pollution system through the harvest, therefore, the application of the ecological repairing method can achieve the purposes of inhibiting the growth of red tide microalgae, and releasing and eliminating eutrophication, and also obtains higher economical value.

The present invention relates to biological processing of garlic, and is especially biological processing method of odorless garlic. The biological processing method of odorless garlic includes the steps of washing, soaking, fermenting and drying, and features that under certain temperature and humidity conditions, the enzyme inside garlic is activated through natural fermentation, so as to eliminate bad smell, improve taste and raise the antioxidant property of garlic. Animal test proves the maintained or even strengthened physiological functions of the deodorized garlic.

The present invention relates to composition combined with natural plant and its preparation method, especially relates to preventing altitude sickness composition and its preparation method. A preventing highland reaction food composition produced by following weight and percentage of the raw materials: red common stonecrop herb 8 to 20 percent, safflower 8 to 20 percent, ginkgo biloba leaves 1 to 80 percent, lanceolata 1 to 70 percent. The method for manufacturing bagged tea of the said preventing altitude sickness food composition is that drying red common stonecrop herb 8 to 20 percent, safflower 8 to 20 percent, lanceolata 1 to 70 percent, and ginkgo biloba leaves 1 to 80 percent under 30 to DEG C and mixing grinding; sieving 40 to 60 mesh sieve, packaging bagged tea, external packing adopts vacuum package. The present invention advantages is that providing a tea, oral liquid, capsule and granule composition and its preparation method, with anti- hypoxia, anti-fatigue, anti-radiation, blood-activation and stasis-eliminating, promoting blood cycle in brain, enhancing immunity effects, and the effects are striking, suitable for each kind symptoms of altitude sickness, without side effects and non-toxic.

The invention provides a blood enriching Chinese traditional medicines. The medicine is made up of fleece-flower root, longan aril longan pulp and other Chinese traditional medicines according to the Chinese medical theory scientifically. The manufacturing method is: the fleece-flower root is produced into processed fleece-flower root, then it is blended with longan aril longan pulp, then they are processed into oral liquid, capsule, particle, tablet through water extraction and alcohol depositing. The medicine has functions of heart and spleen nourishing, qi and blood nourishing, upgrading the hemoglobin haemoglobin, increasing the quantity of erythrocyte, upgrading the HDL-C in high density fat protein, decreasing cholesterol, and preventing senescence. It can be applied to treat diseases caused by weak of heart and spleen, weak of qi and blood, the curative effect is prominent.

The invention discloses a separation method of phenolic acid glucoside compounds in juglans regial L. mature seed diaphragma juglandis fructus and an application, and belongs to the technical field offoods. The method comprises the following steps of (1) performing extraction: crushing the juglans regial L. mature seed diaphragma juglandis fructus, and performing extraction with alcohol to obtainjuglans regial L. mature seed alcohol extracts; and (2) performing separation: performing column chromatography on the juglans regial L. mature seed alcohol extracts obtained in the step (1), sequentially performing eluting with ethanol of different concentrations, performing repeated purifying and eluting, and performing separation to obtain the phenolic acid glucoside compounds, wherein the phenolic acid glucoside compounds are 2-hydroxyl-5-methoxylphenyl-O-beta-D-glucopyranoside, 6-hydroxyl naphthyl-1,2- ( 2-O-beta-D-glucopyranoside) and 2,6-dihydroxy naphthyl -O-beta-D-glucopyranoside. Pharmacological experiments confirm that the three compounds have favorable antioxidant activity.

The invention relates to a malus halliana leaf extract, an extraction method and an application thereof, and belongs to the field of pharmaceutical technology. The malus halliana leaf extract is n-butanol extract and / or ethyl acetate extract of the malus halliana leaf. The extraction method comprises the following steps of dispersing the ethanol extract of the malus halliana leaf in water; extracting with ethyl acetate and n-butanol successively; and volatilizing a solvent. The ethyl acetate extract is the ethyl acetate extract of the malus halliana leaf; and the n-butanol extract is the n-butanol extract of the malus halliana leaf. Experiments demonstrate that the malus halliana leaf extract provided by the invention can effectively clear DPPH and ABTS free radicals and reduce Fe<3+>, so that the malus halliana leaf extract can be used for preparing antioxidants. The extract can significantly reduce GPT and GOT content in serum of mice suffering from acute liver injury and MDA content in mice liver tissues and increase SOD activity, so that the extract can be used for preparing drugs for protecting the liver.

The invention relates to a Lactobacillus with the efficacy of preventing and treating diabetic encephalopathy and a separation method and application thereof. The Lactobacillus is named as a Lactobacillus paracasei LC86 strain, and the preservation unit is China General Microbiological Culture Collection Center, the preservation time is December, 2013, the preservation number is CGMCC 1.12731, andthe address is No. 3, No. 1 Courtyard, Beichenxi Road, Chaoyang District, Beijing City. According to the Lactobacillus, the increase of the content of nitric oxide caused by diabetic encephalopathy can be obviously improved, the antioxidant enzyme activity of brain tissues can be improved, and the learning and memory ability can be improved. The Lactobacillus is applied to medicines for preventing and treating diabetic encephalopathy, has no toxic or side effect, and can be used for treating clinical patients together with other nutrients.

A method for preparing hyperoxide dismutase (SOD) by fermenting shiraia bambusicola belongs to the technical field of bioengineering. The method adopts shiraia bambusicola strain for preparing the SODwhich is mainly exoenzyme under the condition of liquid state fermentation. During the fermentation, the SOD yield can be improved by adding H2O2, surfactant or alkane or by illumination. The maximumSOD yield can be 800 U / mL. During the fermentation, the strain can simultaneously generate quinochromes which can have a yield as high as 1.1 g / L, wherein hypocrellin A accounts for 90 percent and hypocrellin B accounts for 5 percent. Tabasheer is an officinal fungus and mainly generates hypocrellins and other quinochromes by means of fermentation, thereby having high officinal value and healthcare function. The fermentation of the tabasheer to prepare the SOD has the advantage of short fermentation period, the activity of the SOD in fermentation liquid is relatively high, and the quinochromes can be simultaneously generated. The method has a good prospect for industrial application.

The invention belongs to the technical field of traditional Chinese medicine extraction, and particularly to an ainsliaea fragrans champ extract, an extraction method and an application thereof. The ainsliaea fragrans champ extract is an ethyl acetate extract or / and a methanol extract of ainsliaea fragrans champ, and is prepared by using the following method: crushing the whole grass of ainsliaea fragrans champ, adding ethyl acetate, carrying out heating reflux extraction 2-3 times, filtering, respectively mixing the filter residues and the filtrates obtained from the two extractions, carrying out concentration drying on the filtrate to obtain the ethyl acetate extract, carrying out heating reflux extraction 2-3 times on the filter residue with methanol, filtering, mixing the filtrates obtained from the two extractions, carrying out concentration drying on the filtrate to obtain the methanol extract. The ainsliaea fragrans champ extract has anti-oxidation activity and liver protection activity.

The invention relates to the field of medicines, and particularly relates to a ginsenoside composition, a preparing method thereof and applications of the ginsenoside composition. The ginsenoside composition comprises rare ginsenosides Rh4, Rk3, Rk1 and Rg5. Changes of active components in a ginseng steaming process are researched systematically, response surface design tests are utilized to optimize a ginseng processing process, and the inventor unexpectedly found a processing method in which ginsenoside component changes of a raw medicine material are most obvious, and especially unexpectedly found a processing method for efficiently preparing the rare ginsenosides. Through later pharmacological activity screening, the inventor also unexpectedly found that a ginseng processing product rich in the rare ginsenosides has significant kidney and yang tonifying effects.

The invention relates to application of a sika deer spleen extract to antioxidant medicines. Animal experiments show that the sika deer spleen extract prepared by the process provided by the invention can reduce peroxides and protein carbonyls in serum of an ethanol-damaged mouse model, increase the content of reductive glutathione and enhance the activity of SOD in the serum, has an antioxidant effect, and can be used for preparing the antioxidant medicines and health-care food.

The invention discloses yak collagen peptide and an application thereof. The collagen peptide is high-quality Qinghai yak peptide of 3000 Da or lower, has good anti-aging and anti-oxidation effects, can be directly absorbed by a human body and can achieve good beauty and health care effect, and a beauty and health care product prepared from the collagen peptide has good anti-aging effect.

The invention aims to provide an active polypeptide separated from an anchovy fermentation liquid. The molecular weight of the nerve cell injury resistant polypeptide obtained by the invention is 2,181Da; and the polypeptide is composed of 11 amino acids such as aspartic acid, threonine, glutamic acid, glycine, alanine, isoleucine, tyrosine, phenylalanine, histidine, lysine, arginine and the like, and is a novel active polypeptide with activity. According to the polypeptide obtained by the invention, in a glutamine nerve cell injury model, the addition of the active polypeptide provided by the invention can obviously increase the survival rate of PC12 nerve cells; and when the final concentration is 50 mug / mL, the cell survival rate is increased by 26.4% in comparison with an injury group, thereby effectively relieving glutamine-induced nerve cell injury. Besides, the cell mechanism study on the nerve cell protective action of the polypeptide discovers that the addition of the active polypeptide obviously increases the intracellular total oxidation resistance and has a certain promoting action on increase of SOD (superoxide dismutase) activity.

The invention discloses a method for using nano-selenium contained kelp feed to culture selenium-enriched abalone, which includes: adding 440-1485ml of water to evenly dilute 0.50mg / ml red nano-selenium solution with particle size of 100-140nm, spraying the mixed liquor to kelp feed, and culturing for 120-180 days, wherein 0.50-2.0mg of nano-selenium is added per kilogram of the kelp feed, and shell length, weight, SOD (superoxide dismutase), GPX (glutathione peroxidase), survival rate and weight gain rate of the commercial selenium-enriched abalone are all increased evidently as compared with those of a control group. In addition, by comparative test for parameters such as nano-selenium dosage, diluted concentration, shape of kelp feed, culture duration and the like, a best method for culturing the commercial selenium-enriched abalone is further determined. The method is also applicable to production of selenium-enriched sea cucumber, fishes and shrimps.

The invention discloses a pear peel extract as well as an extraction method and an application thereof in blood glucose-reduction health products. The extraction method comprises the following steps: carrying out freezing and drying or vacuum drying on pear peels, mixing the dried pear peel and a methyl alcohol aqueous solution or ethyl alcohol aqueous solution with the concentration of 50-80% in a mass ratio of 1:(10-100), ultrasonically extracting for 0.5-2h for 2-3 times, combining extraction solutions, concentrating, and drying at 40-60 DEG C to enable methyl alcohol or ethyl alcohol to be completely volatilized to obtain extract. The pear peel extract has an obvious effect on reducing blood glucose of diabetic mice, and also has obvious effects on glucose tolerance adjustment, postprandial blood glucose delaying, and improving oxidative stress (improving SOD (superoxide dismutase) activity and reducing MDA (Methane Dicarboxylic Aldehyde) content) of the diabetic mice through in-vivo tests; and the pear peel extract has a remarkable inhibition effect on alpha-glycosidase through in-vitro tests, therefore, the pear peel extract has the effect on postprandial blood glucose delaying.

The invention relates to a novel application of icariin to resisting of oxygen deficiency. Proved by the test in the invention, the icariin has remarkable protecting functions for resisting oxygen deficiency induction and oxygen deficiency damage. The invention also provides an application of the icariin to preparation of a medicinal preparation with an oxygen deficiency resisting function.

The invention relates to rhizoma polygonati health drink and a preparation method thereof. The preparation method is characterized by comprising the steps of squeezing juice from fresh rhizoma polygonati and fresh mulberry fruit to obtain fresh rhizoma polygonati juice and fresh mulberry fruit juice; extracting lily bulb and rhizoma polygonati odorati to obtain extract liquid; evenly mixing; adding stevioside, erythritol, citric acid, sodium citrate, guar gum (a thickener), vitamin C and soybean peptide. The fresh rhizoma polygonati and the fresh mulberry fruit are squeezed into juice, so that nutrient substances of raw materials can be fully kept, and the drink has the effects of reducing blood sugar, resisting fatigue, resisting oxidization, tonifying spleen, moisturizing lung, delaying senescence and the like.

The invention discloses a novel use of catalpol in preparation of a drug for treating cerebral arterial thrombosis reperfusion injuries and belongs to the technical field of medicines. Catalpol can be used for preparation of a drug for treating cerebral arterial thrombosis reperfusion injuries and especially can be used for preparation of a drug for treating cerebral arterial thrombosis reperfusion injuries and neurologic impairment.

The invention discloses a Chinese herba preparation for regulating lipid and reducing weight, made by sticktight, hawthorn, roxburghrose, medlar and salvia miltiorrhiza. The medicines are combined to achieve synergistic effect of efficacies of all medicines, thus effectively removing stasis and activating blood, helping digestion, nourishing liver and kidney and replenishing qi to invigorate the spleen. Most medicines in the invention are food and have definite curative effect, thus being applicable to application for a long time, and price is low, thus being easy to develop and apply.

The present invention relates to biological processing of garlic, and is especially biological processing method of odorless garlic. The biological processing method of odorless garlic includes the steps of washing, soaking, fermenting and drying, and features that under certain temperature and humidity conditions, the enzyme inside garlic is activated through natural fermentation, so as to eliminate bad smell, improve taste and raise the antioxidant property of garlic. Animal test proves the maintained or even strengthened physiological functions of the deodorized garlic.

The invention relates to the technical field of medicines, and concretely relates to N-aryl-beta-carboline derivatives and an application thereof. The synthesis method of the N-aryl-beta-carboline derivatives is simple, and simple in steps. The method comprises the following steps: reacting tryptophan methyl ester with an aldehyde derivative to obtain an indolopyrrole intermediate, then adding anoxidizing agent, performing cyclization to obtain beta-carboline, and finally coupling with aromatic ring derivatives under an alkaline condition to obtain the N-aryl-beta-carboline derivatives. The compounds are low in myocardial cell toxicity, strong in protection capability and high in activity, and the application of the carboline derivatives in myocardial anoxia reoxygenation injury is improved.

The invention discloses a banana peel enzyme fermentation method. The banana peel enzyme fermentation method comprises the following steps: (1) cleaning the banana peels, chopping, soaking in a soaking solution for 3 to 4 hours, filtering, and performing the composite enzyme enzymolysis for the banana peel residues; (2) sterilizing the enzymolyzed banana peel residues, inoculating an activated strain, fermenting for 3 to 4 days, and obtaining a banana peel fermentation solution; and (3) uniformly mixing the banana peel fermentation solution, alpha-arbutin, thiamine mononitrate and disodium creatine phosphate, adding into a vacuum freeze drying machine, drying until the water content is less than 5 percent, and obtaining enzyme powder. The prepared banana peel enzyme is fresh in aroma, hasfermentation fragrance, pure acidic taste, looseness and gloss; and compared with the enzyme products on the market, the protease activity, the SOD activity and the lipase content in the prepared banana peel enzyme powder are significantly improved, probiotics in the product is efficiently reserved, and the product quality can be improved.

The invention discloses an application of an alpha-mangostin derivative alpha-mangostin derivative in preparation of drugs for resisting and treating BPH (benign prostatic hyperplasia) and anti-BPH drug composition. The effective ingredient of the anti-BPH BPH drug composition is the alpha-mangostin derivative. The alpha-mangostin derivative can be absorbed by prostate tissue, still has anti-inflammatory activity, can improve the SOD activity and reduce MDA content and relieves enlargement of a prostate gland, therefore, the alpha-mangostin derivative can be used for treating BPH and has broad application prospects in preparation of the drugs for treating the BPH.

The invention relates to a substance content determination method and an application thereof. The substance is prepared from 225 parts of astragalus membranaceus, 100 parts of leech, 90 parts of ligusticum wallichii, 90 parts of angelica sinensis, 90 parts of safflower carthamus, 113 parts of peach kernel, 90 parts of radix paeoniae rubra, 90 parts of elecampane, 90 parts of rhizoma acori graminei, 60 parts of lumbricus, 90 parts of parasitic loranthus and 35 parts of acanthopanax extract. The content detection method has characteristics of simple and rapid operation and good repeatability andaccuracy. The method is advantaged in that pharmacological experiments of the substance show that the substance can significantly improve the mouse behavior coordination ability, significantly shorten the mouse pole climbing time, enhance the mouse grabbing force and the mouse swimming time, and significantly relieve MPTP-induced neuron damage, the substance content determination method can effectively control the inherent quality of the drug, and the new treatment application of the substance enlarges the clinical medication disease treatment range of the drug.

The invention provides a liver protection de-alcoholic composition and an oral preparation and relates to the technical field of alcoholism prevention. The liver protection de-alcoholic composition ismainly prepared from the following raw materials in parts by weight: 1-5 parts of an oyster extract, 1-150 parts of taurine, 0.1-5 parts of curcumin, 1-10 parts of methionine and 1-15 parts of ornithine. The liver protection de-alcoholic composition can provide alcoholism prevention and liver protection effects, can effectively quicken alcohol metabolism, improves the liver function and the detoxification function of liver, and therefore, has a high market popularization value. The oral preparation comprises the liver protection de-alcoholic composition. On the one hand, the oral preparationcan provide the alcoholism prevention and liver protection effects, effectively quicken alcohol metabolism and improve the liver function and the detoxification function of liver, and therefore, has ahigh market popularization value; and on the other hand, the oral preparation is convenient to eat and easy to store and carry, and therefore, has a high industrial production value.

The invention discloses a preparation method of a lycopene-containing composition with an anti-aging effect, which comprises the following steps: mixing lycopene oleoresin with a small amount of absolute ethyl alcohol to obtain lycopene oleoresin alcoholate, putting the nicotinamide mononucleotide into a fluidized bed granulator, atomizing the lycopene oleoresin alcoholate by a nozzle through compressed air, spraying the lycopene oleoresin alcoholate onto nicotinamide mononucleotide powder in a fluidized state on the fluidized bed layer, wetting and fully mixing the lycopene oleoresin alcoholate and the nicotinamide mononucleotide powder, and performing flow granulation, wherein the conditions for spray granulation are as follows: the atomizing speed of a nozzle is 40-100mL / min, and the atomizing particle size is 10-12 [mu]m. The anti-aging composition prepared by the method disclosed by the invention can effectively prolong the service life of the drosophila melanogaster, improve theclimbing capacity of the drosophila melanogaster, effectively improve the MDA level of rat serum and the SOD activity of the rat serum, and has a remarkable anti-aging effect. Moreover, the granular product is high in content of effective components and good in stability.

The invention belongs to the technical field of medicinal products, and particularly relates to a medicinal composition containing 4-hydroxy-2-oxo-1-pyrrolidine acetamide and application thereof. A 4-hydroxy-2-oxo-1-pyrrolidine acetamide-borneol medicinal composition provided by the invention has a synergistic treatment effect on neuromotor dysfunction and impaired memory dysfunction vascular dementia and senile dementia, and the treatment effect of oxiracetam can be improved remarkably by using borneol, so that the acting dose of oxiracetam is reduced, the dosage is reduced, and adverse reactions are reduced after long-time application. By adopting the medicinal composition, intelligence disturbance of a dementia patient can be treated more effectively, and a treatment effect can be achieved with a small dosage. The medicinal composition is suitable for clinical use.

The invention discloses natural moisturizing cushion blusher. The natural moisturizing cushion blusher comprises the following components: 0.5-2 parts of lily polysaccharides, 0.1-1.5 parts of trehalose, 0.03-0.8 part of cochineal color, 0.05-1.0 part of pitaya red pigment, 2-4 parts of squalane, 1-3 parts of ethylhexyl palmitate, 1-3 parts of ozocerite, 0.01-0.04 part of sodium hyaluronate, 0.1-0.4 part of phenoxyethanol, 0.3-0.8 part of ethylhexylglycerin and 35-70 parts of deionized water. The natural moisturizing cushion blusher disclosed by the invention solves the technical problems that the conventional blusher product easily causes makeup meltdown or easily causes non-uniform coloring, and the safety performance is low.

A health-care composition and an enteric capsule prepared from said health-care composition for improving human immunity and resistance to oxidization, mutation, bacteria and thrombus, decreasing blood fat, and balancing between omega-3 fatty acid and omega-6 fatty acid is prepared from the refined garlic oil as antioxidizing agent and the perilla seed oil as solvent oil.