3results about How to "Extended swim time" patented technology

The present invention provides a codfish white peptide with fatigue-relieving activity, which is prepared by enzymatic hydrolysis of codfish meat using alkaline protease and flavor protease as a composite enzyme; one of its amino acid sequences is LPFQR or VPYPR. The codfish white peptide provided by the present invention can be used to prepare anti-fatigue products. The codfish white peptide with fatigue-relieving effect prepared by the present invention using enzymatic hydrolysis technology simplifies the production process, reduces production costs, and does not cause any pollution. The target codfish white peptide prepared by the present invention has a significant fatigue-relieving effect. Animal experiments have shown that the codfish white peptide can significantly prolong the exhaustive swimming time of mice, reduce the blood lactate and blood urea nitrogen levels of mice, increase the glycogen reserve of mice, improve the levels of ATP and ATPase, can improve muscle damage in mice, and has a good fatigue-relieving effect.

This invention belongs to the field of traditional Chinese medicine fermentation technology, specifically relating to a kidney-tonifying and aphrodisiac fermentation composition and its preparation method. The composition, by weight, comprises 30-60 parts of Cistanche deserticola, 30-60 parts of black truffle, 10-30 parts of black beans, 5-20 parts of Eucommia ulmoides male flowers, 15-30 parts of Codonopsis pilosula, 5-15 parts of enzyme preparation, 0.6-1.4 parts of fermentation starter culture, and 800-900 parts of water. The composition, with Cistanche deserticola and black truffle as the main components, supplemented by black beans, Eucommia ulmoides male flowers, and Codonopsis pilosula, works synergistically to achieve a good kidney-tonifying and aphrodisiac effect after enzymatic fermentation.

The invention discloses a preparation method of a Zhenshi stagnation eliminating decoction and application of the Zhenshi stagnation eliminating decoction in pancreatic cancer treatment, and belongs to the technical field of traditional Chinese medicines. The preparation method comprises the following steps: weighing 6-12 parts by weight of radix bupleuri, 8-15 parts by weight of codonopsis pilosula, 10-15 parts by weight of fried coix seed, 6-12 parts by weight of rhizoma bolbostemmae, 12-20 parts by weight of turtle shell, 8-15 parts by weight of pericarpium citri reticulatae, 6-12 parts by weight of fried immature bitter orange and 2-5 parts by weight of coptis chinensis; the medicinal materials are decocted twice and then concentrated into extract with the relative density of 1.10-1.25 to prepare a water decoction, and the water decoction can be further processed into granules or tablets. By up-regulating Bax protein and down-regulating Bcl-2 and Bcl-xl protein expression, the decoction induces tumor cell apoptosis, inhibits mouse pancreatic cancer transplantation tumor growth, maintains tumor-bearing mouse body mass and prolongs swimming time, and the safety of the decoction is obviously superior to that of chemotherapy drugs; according to the invention, the traditional Chinese medicine theory and modern pharmacology are combined, the anti-pancreatic cancer traditional Chinese medicine compound with multiple targets and low toxic and side effects is provided, the compound has high efficiency, repeatability and dosage form diversity, and the blank of the traditional Chinese medicine compound in accurate treatment of pancreatic cancer is filled.