46 results about "Blood lactate" patented technology

Provided are methods for enhancing exercise (e.g., intense, eccentric, elevated temperature, repetitive, aerobic, and high altitude) performance, comprising administering electrokinetically-altered aqueous fluids comprising an ionic aqueous solution of stably configured charge-stabilized oxygen-containing nanostructures predominantly having an average diameter of less than 100 nanometers. In certain aspects, enhancing exercise performance comprises at least one of: reducing plasma inflammatory cytokines (e.g., IFN-alpha, ENA-78 and BDNF); ameliorating muscle / tendon damage or enhancing muscle / tendon recovery; reducing biomarkers of exercise-induced muscle injury (e.g., CK, plasma myoglobin); ameliorating exercise induced tendinosis, tendonitis, tenosynovitis, avulsion, and tendon strain associated with chronic repetitive movement or enhancing recovering therefrom; increasing VO2 max; decreasing RPE; reducing blood lactate; preserving muscle contractile function (e.g., maximal force, joint ROM); reducing muscle soreness; ameliorating onset of fatigue in an excercising subject. Improved methods for producing electrokinetically altered aqueous fluids (including sports beverages) are also provided.

The invention discloses auricularia auricula polysaccharides energy gel with an anti-fatigue function and belongs to the technical field of food for special use. The energy gel is composed of an auricularia auricula polysaccharides concentrated solution, soy isolate protein, whey protein, fructose, cane sugar, vegetable oil, maltodextrin, gelatin and a quality improver. Weight percentage of the above ingredients is as follows: content of the auricularia auricula polysaccharides concentrated solution is 21-35.5%, content of whey protein is 1-4%, content of soy isolate protein is 1-4%, total content of fructose and cane sugar is 16-40%, total content of vegetable oil is 12-15%, content of maltodextrin is 12-18%, and total content of gelatin and the quality improver is 6-14.3%. The auricularia auricula polysaccharides energy gel can obviously prolong load swimming time of mice and reduce contents of blood lactic acid and blood urea nitrogen, and simultaneously has an effect of increasing glycogen reserves of body and has obvious anti-fatigue and fatigue-removal effects.

The invention relates to a composition having muscle power fatigue alleviating and anoxic tolerance improving effects. The composition is prepared by using L-arginine, L-citrulline, taurine, vitamin C, vitamin E powder and folic acid according to a prescribed ratio. Animal function tests prove that the composition can obviously prolong the weight bearing swimming time of mice, prolong the viability time of the mice under normal pressure anoxic conditions, obviously reduce the urea nitrogen and blood lactic acid content of serum of post-exercised mice, and increase the liver starch content of mice during exercise; and results of human feeding tests show that the composition can improve the maximum oxygen consumption of subjects, reduce the blood lactic acid rise after exercise and increase the exercise tolerance of bodies. The composition has muscle power fatigue alleviating and anoxic tolerance improving effects.

The invention provides an anti-fatigue healthcare product or pharmaceutical composition and a preparation method and application thereof. The healthcare product or the pharmaceutical composition is prepared from, by weight, 50-90 parts of acanthopanax root, 30-50 parts of glossy ganoderma, 30-50 parts of wolfberry fruit and 60-110 parts of green tea. The healthcare product or the pharmaceutical composition is capable of effectively reducing organism serum urea nitrogen and blood lactic acid content and obviously prolonging load swimming time and has a good anti-fatigue effect. Besides, the healthcare product or the pharmaceutical composition is capable of increasing radiated mouse SOD (superoxide dismutase) activity, increasing white blood cells, lowering marrow micronucleus rate and increasing animal survival rate, has a remarkable anti-radiation function and is safe, non-toxic, good in taste and suitable for long-term taking.

The invention provides a whole blood lactate / blood sugar test strip and an integrated blood taking needle packaging the test strip. The test strip is an electrochemical biosensor comprising a testing electrode plate, a cover plate and a reaction reagent layer, a capillary tube cavity body with two open ends is formed between the testing electrode plate and the cover plate, and the reaction reagent layer is formed on the inner wall of the capillary tube cavity body. The integrated blood taking needle for packaging the test strip has a blood taking needle point arranged on one end of a needle bar, and the other end thereof is provided with a U-shaped slot, and the test strip is mounted in the U-shaped slot. The test strip of the invention can automatically soak up trace amount of blood sample and complete the test process of blood lactate / blood sugar in a short time; and the test strip is packaged in the blood taking needle, so the test strip can be taken out for test after collecting the blood sample. The test strip and the blood taking needle of the invention have advantages of providing two detection indexes of blood lactate and blood sugar by one sampling; simple design, low cost, easy processing and making, easy batch production, and convenient carrying and usage.

The present invention belongs to the field of health-care food and particularly relates to a fatigue preventing health-care food composition and a health-care food preparation. Oligopeptides originated from wheat proteins, soybean proteins and animal collagen are combined, then apricot kernel powder, red date powder, oatmeal and cheese powder ingredients are added for the fatigue preventing health-care food, and the health-care food composition can effectively improve the changes of metabolites of hepatic glycogen content, serum urea nitrogen content, blood lactate acid content, etc. under body fatigue state and effectively improve the body health status.

Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.

The invention provides a nutritional supplement which can improve the sports explosive force and comprises the main components of creatine compound, carbohydrate and D-ribose. The invention which matches and uses the creatine, carbohydrate and D-ribose can simultaneously promote the re-synthesis of the ATP in the body in three different ways so as to play the role in improving the sports explosive force. The administration of the nutritional supplement of the invention has the effects of improving the ability of anaerobic exercise and sports explosive force and is helpful to reducing the value of blood lactate after high intensity exercise and the fast recovery after exercise.

An exercise-effect determining method includes measuring a pulse wave signal and a body motion signal of a user at the time when the user is performing predetermined exercise, calculating a pulse rate during exercise on the basis of the pulse wave signal and the body motion signal, obtaining, on the basis of lactate level information representing a relation between a pulse rate and a blood lactate level of the user acquired in advance and the pulse rate during exercise, an exercise-effect determination result of determination of an effect degree of the predetermined exercise contributing to physical strength of the user, and informing the user of the exercise-effect determination result.

Some embodiments described herein relate to receiving lactate concentration data from a non-invasive sensor. A ratio of aerobic to anaerobic exertion can be determined based on the concentration of lactate, and real-time feedback can be provided based on the ratio of aerobic to anaerobic exertion. For example, the user can be encouraged to maintain a level of intensity in which he or she approaches (but does not exceed) maximal oxygen consumption.

The invention relates to an extract product capable of preventing oxidation, delaying aging, and nourishing heart and cerebral vessels, and a preparation method thereof. According to the preparation method, a grape extract and a mixed fruit powder are prepared firstly, and are mixed with yeast for fermentation, after metabolism of yeast, organic conversion of resveratrol in the grape extract, andanthocyanidin and a plurality of trace elements in the mixed fruit powder is realized, so that adsorption on nutrients is improved, and the biological value is increased. It is confirmed by animal experiments that the extract product is capable of prolonging mouse life time and rat loaded swimming time obviously, reducing blood urea nitrogen content, reducing blood lactic acid accumulation, and increasing hepatic glycogen content, possesses obvious anti-fatigue activity, is capable of increasing the activity of superoxide dismutase in rat serum, and accelerating malonaldehyde removing rate, and possesses obvious anti-oxidation activity. The extract product is prepared from pure natural materials, no chemical raw material is added, no toxic or side effect is caused by long term eating. Theextract product is suitable for fatigable people, people high in cholesterol content, and people with long term smoking and drinking habits.

The invention discloses health-care food with an anti-fatigue effect and a preparation method thereof. The health-care food is prepared from the following raw materials in part by weight: 300 to 450 parts of lophatherum gracile Brongn and 250 to 400 parts of American ginseng. A health-care product preparation provided by the invention has the advantages of obviously prolonging the burden swimming time of mice, reducing the production of serum urea nitrogen of the mice, reducing area under curve of blood lactate after the motion of the mice along with the anti-fatigue health-care effect. The health-care food adopts medicinal and edible natural plants as main raw materials, so that the preparation process and the product quality is stable and controllable; the curative effect is obvious; the provided formulation is convenient to administrate; and the health-care food is suitable for all kinds of people to eat.

The invention belongs to the technical fields of biomedical engineering, as well as electronic technology and information, and specifically relates to a wearable multi-functional respiratory circulation detection system and a wearable multi-functional respiratory circulation detection method. The wearable multi-functional respiratory circulation detection system comprises an upper industrial personal computer, and a lower computer; the lower computer comprises a signal processing module, a signal acquisition module, and a wireless transmission module; the signal acquisition module comprises anelectrocardiogram (ECG) electrical sensor module, a chest impedance electrical sensor module, and a blood lactate and pulse wave photoelectric sensor module; the signal processing module of the lowercomputer controls a bluetooth module to transmit detected signals to the upper industrial personal computer; the upper industrial personal computer comprises a signal processing computer; and an ECGsignal model, a chest impedance ICG signal model, a theoretical critical power model of aerobic and anaerobic respiration in exercise, a pulse wave signal model, a cardiopulmonary function index modeland a signal denoising and processing system are arranged inside the signal processing computer. The wearable multi-functional respiratory circulation detection system is capable of measuring signalsof the human body with high precision under static, breathing and moving conditions; and moreover, the wearable multi-functional respiratory circulation detection system is high in instrument anti-interference ability.

The present invention relates to a device for accurately estimating the energy expenditure of a person, in particular by which the effect of cardiovascular drift is taken into account. The device comprises an input unit (10) for obtaining a movement signal (13) representing physical activity of the person and a heart rate signal (15) representing the heart rate of the person, a cardiovascular drift determination unit (16) for determining cardiovascular drift phases (17) from said movement signal (13) and either said heart rate signal (15) and / or one or more cardiovascular drift related signals (23) carrying information on one or more of amount of sweat, weight loss, temperature rise, blood lactate concentration and physical fatigue of the person, a correction unit (18) for correcting the heart rate signal (15) generated and representing the heart rate during a cardiovascular drift phase, and an estimation unit (20) for estimating the energy expenditure of the person from the corrected heart rate signal (19).

The current invention pertains to an apparatus and method for the determination of excess post-exercise oxygen consumption (EPOC) and the estimation of blood lactate levels. While these exercise parameters are traditionally determined using indirect calorimetry and blood sampling, this invention provides a method for the determination of these parameters using heart rate data. A wearable photoplethysmography device for measuring heart rate is included as an exemplary embodiment, however, the method of the current inventions can also be used with heart rate data from any heart rate monitor. In an embodiment of the present invention a supply demand differential equation is used to continuously monitor EPOC in real-time. Furthermore, blood lactate levels can also be estimated as a function of EPOC. Importantly, the process of determining EPOC and blood lactate can be linked to a biomathematical model of human physiology to access additional parameters such as hormonal changes, body composition changes or other physiological fluctuations or transient physiological behavior.

The invention relates to an application of 5' nucleotide in preparation of medicines and health-care foods for alleviating physical fatigue. The nucleotide is 5' nucleotide mixture which takes ribonucleic acid (RNA) as raw material, produced by enzymic degradation, has the purity of more than 99%, and is prepared by mixing 5' AMP, 5' CMP, 5' GMPNa2 and 5' UMPNa2 according to the mixture ratio of 22.8:26.6:30.2:20.4. The nucleotide can reduce and prolong the mouse burden swimming time, decreases the generation of blood lactate after movement, lowers the serum urea nitrogen level and has the function of alleviating physical fatigue.

The invention relates to a vitamin replenisher applicable to sports group, which mainly comprises the following compositions by weight proportion: 45,000 to 67,600 mu g of vitamin A, 90 to 150 mg of vitamin B1, 90 to 150 mg of vitamin B2, 6,000 to 9,500 mg of vitamin C, 100 to 160 mg of vitamin B6, 900 to 1,500 mg of vitamin E, 1,000 to 1,550 mg of nicotinic acid, 13,000 to 21,000 mu g of folic acid, 220 to 350 mu g of vitamin D, and 90 to 140 mu g of vitamin B12. The vitamin replenisher provided by the invention is prepared according to nutritional survey result of 240 sports people in 17 sports events of national teams and provincial and municipal professional sports teams in 5 national and provincial sports science institutes, not only can replenish nutrients lacking in sports people, but also is advantageous to blood lactate elimination and sports achievements of the sports people.

An isolated lactic acid bacteria strain: Bifidobacterium longum subsp. longum OLP-01 strain for increasing exercise performance and ameliorating fatigue is disclosed. A variety of animal experiments have proved that OLP-01 not only effectively improves muscle strength and swimming endurance but also significantly reduces fatigue-related biochemical indicators, including blood lactate, blood urea nitrogen and the activity of creatine kinase.

Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.

Systems, techniques and methods for estimating the metabolic state or flux, e.g., the body energy state (“BES”) of a patient, are disclosed. The BES provides a deep insight into the nutritional needs of the patient, thus allowing for a sort of exquisite glycemic control with regard to the patient. The invention discloses systems and methods for estimating fractional gluconeogenesis. The invention also discloses systems and methods for estimating and targeting patient blood lactate concentration, both as a target itself and as an intermediate step to estimating and targeting patient fractional gluconeogenesis glucose production. Nutritional support methods and formulations are also disclosed. The invention is suitable for any sort of patient, including those who are injured, such as with traumatic brain injury, ill, or have other conditions that stress the metabolic system.

The present invention is directed to methods for reducing blood lactate concentration during exercise, physical activity or athletic performance.

Provided are methods for enhancing exercise (e.g., intense, eccentric, elevated temperature, repetitive, aerobic, and high altitude) performance, comprising administering electrokinetically-altered aqueous fluids comprising an ionic aqueous solution of stably configured charge-stabilized oxygen-containing nanostructures predominantly having an average diameter of less than 100 nanometers. In certain aspects, enhancing exercise performance comprises at least one of: reducing plasma inflammatory cytokines (e.g., IFN-alpha, ENA-78 and BDNF); ameliorating muscle / tendon damage or enhancing muscle / tendon recovery; reducing biomarkers of exercise-induced muscle injury (e.g., CK-, plasma myoglobin); ameliorating exercise induced tendinosis, tendonitis, tenosynovitis, avulsion, and tendon strain associated with chronic repetitive movement or enhancing recovering therefrom; increasing VO2 max; decreasing RPE; reducing blood lactate; preserving muscle contractile function (e.g., maximal force, joint ROM); reducing muscle soreness; ameliorating onset of fatigue in an exercising subject. Improved methods for producing electrokinetically altered aqueous fluids (including sports beverages) are also provided.

The treatment of diabetes mellitus with excellent hypoglycemic effect that suppresses lactic acidosis without substantially increasing the blood lactate concentration. A composition for treating diabetes mellitus with hypoglycemic effect that suppresses lactic acidosis without substantially increasing the blood lactate concentration, and the composition has branched-chain amino acids and salts of biguanide derivatives and derivatives of biguanide derivatives or branched-chain amino acids as the active components. The composition will be more effective when leucine, isoleucine, or valine is included as branched-chain amino acids, and metformin as the biguanide derivative.

The invention relates to an application of trehalose to antifatigue medicines, health-care products and movement foods. The trehalose has a purity of greater than 98% and is sold in the market. Through animal experiments, the inventor finds that the trehalose can prolong the weight loading swimming time of mice, can increase the liver starch content, can reduce generation of serum urea nitrogen during swimming of the mice, and can reduce the level of blood lactate after movement of the mice. The experiments prove that the trehalose has good weariness resisting activity.

The invention discloses a healthcare product for relieving physical fatigue and a preparation method of the healthcare product for relieving physical fatigue. The method includes: subjecting Lycium barbarum to alcohol extraction, subjecting flos chrysanthemi, rhodiola rosea and Lycium barbarum residues to water extraction, concentrating and drying to obtain dry extracts, uniformly mixing with yams, grinding to obtain mixed powder, and encapsulating to obtain the healthcare product for relieving physical fatigue. Compared with the prior art, the healthcare product for relieving physical fatigue is prepared from traditional Chinese medicinal materials, simple in prescription and reasonable in ingredient and has functions of spleen tonifying, stomach nourishing, body fluid regenerating, lung benefiting and fatigue resistance, and effective rate of the anti-fatigue function of the product is 100% approximately. The healthcare product prepared according to the method is pretty convenient for human body to absorb. According to experiments in mice, swimming exhausting time of an experimental mouse burdened with a lead sheath in weight 5% of the body weight of the mouse is evidently longer than a blank control group, and difference between the blank control group and each of a high-dose group and a middle-dose group is pretty evident. According to blood lactate measurement, the healthcare product gives play to the anti-fatigue function by means of acceleration of elimination of blood lactates.

The invention provides application of isoliquiritigenin to preparation of drugs used for improving or treating exercise-induced fatigue, and a pharmaceutical composition. The pharmaceutical composition is a preparation prepared from isoliquiritigenin used as a main active component and a pharmaceutically acceptable adjuvant, wherein the adjuvant may be any acceptable excipient, and a weight ratio of isoliquiritigenin to the adjuvant is 10: 90 to 90: 10. According to the invention, an animal model is constructed in the process of research of isoliquiritigenin, and the variation levels of hepatic glycogen, blood lactate and blood urea nitrogen in mouse samples are detected; and isoliquiritigenin is proved to have prevention effect on exercise-induced fatigue, and the pharmaceutical composition capable of preventing exercise-induced fatigue is prepared.

The invention discloses a healthcare product for relieving physical fatigue and a preparation method of the healthcare product for relieving physical fatigue. The method includes: subjecting Lycium barbarum to alcohol extraction, subjecting flos chrysanthemi, rhodiola rosea and Lycium barbarum residues to water extraction, concentrating and drying to obtain dry extracts, uniformly mixing with yams, grinding to obtain mixed powder, and encapsulating to obtain the healthcare product for relieving physical fatigue. Compared with the prior art, the healthcare product for relieving physical fatigue is prepared from traditional Chinese medicinal materials, simple in prescription and reasonable in ingredient and has functions of spleen tonifying, stomach nourishing, body fluid regenerating, lung benefiting and fatigue resistance, and effective rate of the anti-fatigue function of the product is 100% approximately. The healthcare product prepared according to the method is pretty convenient for human body to absorb. According to experiments in mice, swimming exhausting time of an experimental mouse burdened with a lead sheath in weight 5% of the body weight of the mouse is evidently longer than a blank control group, and difference between the blank control group and each of a high-dose group and a middle-dose group is pretty evident. According to blood lactate measurement, the healthcare product gives play to the anti-fatigue function by means of acceleration of elimination of blood lactates.

The current invention pertains to an apparatus and method for the determination of excess post-exercise oxygen consumption (EPOC) and the estimation of blood lactate levels. While these exercise parameters are traditionally determined using indirect calorimetry and blood sampling, this invention provides a method for the determination of these parameters using heart rate data. A wearable photoplethysmography device for measuring heart rate is included as an exemplary embodiment, however, the method of the current inventions can also be used with heart rate data from any heart rate monitor. In an embodiment of the present invention a supply demand differential equation is used to continuously monitor EPOC in real-time. Furthermore, blood lactate levels can also be estimated as a function of EPOC. Importantly, the process of determining EPOC and blood lactate can be linked to a biomathematical model of human physiology to access additional parameters such as hormonal changes, body composition changes or other physiological fluctuations or transient physiological behavior.