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Application of trehalose to antifatigue medicines, health-care products and movement foods

A technology of trehalose and health products, applied in trehalose, the preparation of anti-fatigue drugs or health products and sports food, can solve the problems of not being able to meet the needs of consumers, limited drugs and methods, etc., and achieve the reduction of blood lactic acid level , Improve swimming time, strong anti-fatigue activity

Inactive Publication Date: 2020-10-16
TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drugs and methods to treat fatigue are very limited and cannot meet the needs of consumers
Although traditional Chinese medicine has great potential to delay fatigue, it also has certain side effects

Method used

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  • Application of trehalose to antifatigue medicines, health-care products and movement foods
  • Application of trehalose to antifatigue medicines, health-care products and movement foods
  • Application of trehalose to antifatigue medicines, health-care products and movement foods

Examples

Experimental program
Comparison scheme
Effect test

Embodiment

[0013] Embodiment: Animal experiments evaluate the anti-fatigue activity of trehalose:

[0014] (1) The test sample is commercially available trehalose with a purity greater than 98%.

[0015] (2) Experimental animals Male BALB / c mice, clean animals, four weeks old, were raised in a clean animal room with a temperature of 23 ± 2°C, a humidity of 55 ± 10%, a 12-hour light-dark cycle, pelleted feed, and free access to water.

[0016] (3) Test items: serum lactic acid, blood urea nitrogen content, liver glycogen content.

[0017] (4) Experimental method: the mice were randomly divided into two experimental groups, 40 in each group, and each experimental group included a blank control group, a sucrose control group (90mg / kg), a trehalose low-dose group (90mg / kg ), trehalose high-dose group (180mg / kg), 10 rats in each group (n=10), administered by intragastric administration, the blank control group was administered with distilled water, and the sucrose control group was administe...

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Abstract

The invention relates to an application of trehalose to antifatigue medicines, health-care products and movement foods. The trehalose has a purity of greater than 98% and is sold in the market. Through animal experiments, the inventor finds that the trehalose can prolong the weight loading swimming time of mice, can increase the liver starch content, can reduce generation of serum urea nitrogen during swimming of the mice, and can reduce the level of blood lactate after movement of the mice. The experiments prove that the trehalose has good weariness resisting activity.

Description

technical field [0001] The invention relates to the fields of food health care and medicine, in particular to the application of trehalose in the preparation of anti-fatigue medicine or health care products and sports food. Background technique [0002] Fatigue is the state in which the body's physiological process cannot maintain its function at a specific level or when each organ cannot maintain its predetermined exercise intensity. The resulting protective response manifests itself as a decline in motor function and work efficiency. The main cause of body fatigue is glycogen depletion and lactic acid accumulation. Due to the increased energy demand of the body during exercise and insufficient aerobic metabolism, energy must be provided through anaerobic glycolysis. [0003] Although fatigue is a common physiological state of the body, the decline in exercise capacity, work efficiency, and changes in central and peripheral nerve sensitivity caused by fatigue cannot be ign...

Claims

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Application Information

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IPC IPC(8): A61K31/7016A61P39/00A23L33/125
CPCA23V2002/00A61K31/7016A23L33/125A61P39/00A23V2250/636A23V2200/30
Inventor 张泽生孙立杨
Owner TIANJIN UNIVERSITY OF SCIENCE AND TECHNOLOGY
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