Anti-liver cancer health product containing isoalantolactone

A technology of isoalactone and anti-liver cancer, applied in the direction of medical preparations containing active ingredients, antineoplastic drugs, organic active ingredients, etc., can solve the problems of increasing the survival time of patients, toxic and side effects, etc., to avoid toxic and side effects, Significant and wide-ranging effects of control

Inactive Publication Date: 2018-11-02
LIAONING UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, most chemical drugs for the treatment of liver cancer have strong toxic and side effects. Therefore, it is of great significance to find and develop natural drugs against liver cancer for the prevention and treatment of liver cancer and to increase the survival time of patients.

Method used

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  • Anti-liver cancer health product containing isoalantolactone
  • Anti-liver cancer health product containing isoalantolactone

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0020] Example 1 Anti-hepatocarcinoma health product containing isoinulin

[0021] (1) Preparation of isoinulin

[0022] The process combination of crushing-ethanol extraction-microwave-assisted extraction step-by-step method is used to extract isoinulin, the steps are as follows:

[0023] 1) Crushing of Inulin: take an appropriate amount of dried Inulin rhizome, pulverize it for 10-20min with a grinder, and pass through a 200-mesh sieve to obtain Inulin powder;

[0024] 2) Ethanol extraction: According to the ratio of material to liquid of 1:10-1:20, the inulin powder is dissolved in ethanol with a volume percentage of 70-90%, and extracted at room temperature for 20-24 hours to obtain an ethanol extraction mixture ;

[0025] 3) Microwave-assisted extraction: microwave the ethanol extraction mixture at a temperature of 40-60°C and an extraction time of 170-200s, centrifuge, and take the supernatant;

[0026] 4) Concentrate the supernatant by rotary evaporation, filter it with a filter ...

Embodiment 2

[0054] Example 2 Anti-hepatocarcinoma health products containing isoinulin

[0055] (1)-(5) Same as Example 1.

[0056] (6) Anti-hepatocarcinoma health care products containing isoinulin, consisting of the following raw materials in weight percentage:

[0057] Isochrysalactone 80%, Scutellaria barbata extract 5%, Saffron seed extract 5%, Prunella vulgaris extract 5%, and Lacquer extract 5%.

Embodiment 3

[0058] Example 3 Anti-hepatocarcinoma health products containing isoinulin

[0059] (1)-(5) Same as Example 1.

[0060] (6) Anti-hepatocarcinoma health care products containing isoinulin, consisting of the following raw materials in weight percentage:

[0061] Isochryslide 70%, Scutellaria barbata extract 5%, Saffron seed extract 10%, Prunella vulgaris extract 10%, and Lacquer extract 5%.

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Abstract

The invention discloses an anti-liver cancer health product containing isoalantolactone. The raw materials include, by weight percentage, 60-80% of isoalantolactone, 5-10% of a herba scutellariae barbatae extract, 5-10% of a fructus polygoni orientalis extract, 5-10% of a prunella vulgaris extract and 5-10% of a euphorbia helioscopia extract. The pioneering technology adopted by the invention usesisoalantolactone as the anti-liver cancer core functional raw material, puts forward the Chinese medicinal composition treating liver cancer, and through reasonable compatibility, the anti-liver cancer Chinese herbal medicine mixed health product is formed. Experimental study on human in vitro liver cancer cells finds that the isoalantolactone composition has good inhibition effect on in vitro tumor cells and good control effect on liver cancer, can avoid excessive toxic and side effects of chemical synthetic drugs on the human body, and also has wide sources, thus having good application prospects.

Description

Technical field [0001] The invention belongs to the field of health products, and specifically relates to an anti-hepatocarcinoma health product containing isoinulin. Background technique [0002] Liver cancer is the third leading malignant tumor disease in the world. About 383,000 people die from liver cancer each year in my country, accounting for 51% of the world’s deaths from liver cancer. It is the country with the highest incidence and death rate of liver cancer in the world. Liver cancer has a high degree of malignancy, strong infiltration and metastasis, and poor recovery. The poor sensitivity of liver cancer to chemotherapy is one of the important reasons for the failure of liver cancer treatment. In clinical treatment, the 5-year survival rate of liver cancer patients is only about 10%. At present, most of the chemical drugs used to treat liver cancer have strong side effects. Therefore, finding and developing natural drugs with anti-liver cancer is of great significa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/704A61P35/00A61K31/365
CPCA61K31/365A61K36/47A61K36/536A61K36/539A61K36/704A61K2236/333A61K2236/51A61P35/00A61K2300/00
Inventor 刘剑利杨志军夏莹刘丹毕若尘
Owner LIAONING UNIVERSITY
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