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Traditional Chinese medicine composition used for treating coronary heart disease and preparing method of traditional Chinese medicine composition

A composition and technology for coronary heart disease, applied in the directions of drug combinations, pharmaceutical formulations, cardiovascular system diseases, etc., can solve problems such as unsatisfactory drug efficacy, patient tolerance, treating symptoms but not the root cause, etc., to improve microcirculation, Reduce vascular resistance and enhance immunity

Inactive Publication Date: 2018-06-15
NANYANG INST OF TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] Although western medicine and western medicine have many drugs for treating coronary heart disease and anti-angina pectoris, patients will develop tolerance to them after long-term use, which makes the curative effect of the drugs often unsatisfactory. Western medicine usually uses lipid-lowering drugs and thrombolytic drugs in combination. In order to achieve the purpose of reducing platelet viscosity and dilating coronary arteries, but the symptoms are not the root cause
And long-term use of western medicine may cause dizziness, headache, rapid heartbeat, flushing, liver damage, kidney toxicity and other side effects

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0044] The present embodiment is a traditional Chinese medicine composition for treating coronary heart disease, comprising the following raw materials in parts by weight: Astragalus 25g, Guizhi 6g, Hawthorn 15g, Salvia miltiorrhiza 15g, Caulis Spatholobus 15g, Alisma 10g, Angelica 10g, Chenpi 15g, Bellflower 15g, Capillary 5g, Sophora flavescens 20g, Coptis 3g, Suanzaoren 12g.

[0045] The preparation method of the above-mentioned traditional Chinese medicine composition comprises the following steps: weighing each raw material according to the above weight, mixing each raw material medicine, adding ethanol equivalent to 6 times the total weight of each raw material medicine, soaking for 1.0 h, and then heating and extracting at 80°C 3 times, 1 hour each time, combine the extracts; take the supernatant after standing still, then filter through 140 mesh, and then ultrafilter through an ultrafiltration column with a molecular weight cut-off of 5000, and concentrate the ultrafiltra...

Embodiment 2

[0047] The present embodiment is a traditional Chinese medicine composition for treating coronary heart disease, comprising the following raw materials in parts by weight: Astragalus 30g, Guizhi 8g, Hawthorn 10g, Salvia miltiorrhiza 20g, Caulis Spatholobus 20g, Alisma 15g, Angelica 10g, Chenpi 10g, bellflower 10g, capillary 10g, flavescens 15g, berberine 6g, jujube seed 24g.

[0048] The preparation process of the above-mentioned Chinese medicine composition is the same as that of Example 1, except that the formula of the Chinese medicine composition is different.

Embodiment 3

[0050] The present embodiment is a traditional Chinese medicine composition for treating coronary heart disease, comprising the following raw materials in parts by weight: 45g of astragalus, 12g of cassia twig, 25g of hawthorn, 25g of salvia miltiorrhiza, 35g of Caulis Spatholobus, 15g of Alisma, 30g of angelica, tangerine peel 15g, Bellflower 14g, Capillary 15g, Sophora flavescens 25g, Coptis 9g, Suanzaoren 30g.

[0051] The preparation process of the above-mentioned Chinese medicine composition is the same as that of Example 1, except that the formula of the Chinese medicine composition is different.

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition used for treating a coronary heart disease. The traditional Chinese medicine composition is prepared from, by weight, 20-45 parts ofradix astragali, 6-12 parts of ramulus cinnamomi, 15-30 parts of fructus crataegi, 10-30 parts of radix salviae miltiorrhizae, 15-40 parts of caulis spatholobi, 10-20 parts of rhizoma alismatis, 10-35parts of radix angelicae sinensis, 15-20 parts of tangerine peel, 15-20 parts of radix platycodi, 5-20 parts of herba artemisiae scopariae, 20-45 parts of radix sophorae flavescentis, 3-15 parts of rhizoma coptidis and 12-40 parts of semen ziziphi spinosae. The traditional Chinese medicine composition has the efficacies of invigorating qi, promoting qi to activate blood, discarding the turbid, dissipating phlegm and removing blood stasis, clearing away heat, activating meridians to relieve pain, invigorating the spleen, strengthening the heart and soothing the nerves and is applicable to a coronary heart disease patient who suffers from qi stagnation, blood stasis and phlegm retention, blood deficiency, dryness heat and disturbance; in clinical experiment, the traditional Chinese medicinecomposition has an obvious treatment effect, the total effective rate reaches up to 91%, and the marked effective rate reaches up to 71%.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicines, in particular to a traditional Chinese medicine composition for treating coronary heart disease and a preparation method thereof. Background technique [0002] Coronary atherosclerotic heart disease is coronary atherosclerosis that narrows or blocks the vascular lumen, or (and) causes myocardial ischemia, hypoxia, or necrosis due to functional changes (spasm) in the coronary arteries. Or chest discomfort is the clinical syndrome of main manifestation, is common clinical disease, frequently-occurring disease. The disease mostly occurs in people over the age of 40, more men than women, and more mental workers. The incidence of the disease increases year by year, and it has become an invisible killer that endangers human health. Therefore, the comprehensive research on this disease is of great significance to promote the physical and mental health of human beings and improve t...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/884A61P9/10
CPCA61K36/232A61K36/282A61K36/346A61K36/481A61K36/486A61K36/489A61K36/537A61K36/54A61K36/718A61K36/725A61K36/734A61K36/752A61K36/884A61K2236/33A61K2236/331A61K2236/39A61K2236/55A61K2300/00
Inventor 杨雷刘暖付卫云毛秉豫张千一刘萍赵威李星
Owner NANYANG INST OF TECH
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