A kind of fat-reducing pharmaceutical preparation for weight loss and preparation method thereof

A pharmaceutical preparation and lipid-lowering technology, which is applied in the field of biomedicine, can solve the problems of low preparation efficiency, limited efficacy, and long use time, and achieve the effect of increasing extraction volume, less toxic and side effects, and simple operation

Active Publication Date: 2021-01-05
ZAOZHUANG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0006] But, the defective of above-mentioned two prior art is: although it has carried out quantitative analysis control to the active ingredient of Chinese herbal medicine, this control is only limited to the application of detection means, and its preparation method is still traditional decoction, filtration, concentrating. , granulation step, no further purification process is used to increase the content of active ingredients in Chinese medicine preparations, that is, the content of active ingredients in Chinese medicine preparations is still low
[0010] The defects of this prior art are: 1. Although the content and purity of active ingredients have been improved, the preparation process has many steps, takes a long time, and the preparation efficiency is low, which is not conducive to large-scale production; 2. When the extract is adsorbed, even The use of macroporous resin adsorption is poor in pertinence, which increases the probability of ineffective macromolecules being mixed in, increases the difficulty of subsequent extraction steps, and reduces the content of active ingredients in preparations; 3. One extraction method only targets one type of Chinese medicinal material , the obtained active ingredients are limited, and the efficacy is limited; 4, for the various components of anthraquinone compounds I-IV that all have lipid-lowering functions, it is not necessary to separate them in the process of preparing pharmaceutical preparations

Method used

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  • A kind of fat-reducing pharmaceutical preparation for weight loss and preparation method thereof

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Experimental program
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Effect test

Embodiment

[0039] A weight-loss and lipid-lowering pharmaceutical preparation provided in this example, its active ingredients include anthraquinone compounds, flavonoids and saponins, the mass ratio of the three is 18:8:1.5; the anthraquinone compounds include Polygonum multiflorum , the total anthraquinones in cassia seed and knotweed; the flavonoids include the total flavonoids in hawthorn, lotus leaf and tangerine peel; the saponins include the total saponins in astragalus and saponins.

[0040] Wherein, the mass ratio of the Radix Polygoni Multiflori, Semen Cassiae and Polygonum cuspidatum is 2:1:1; the mass ratio of the hawthorn, lotus leaf and tangerine peel is 2:1:1; the mass ratio of the Radix Astragali and Radix Glycyrrhizae is 1: 1.

[0041] A weight-loss and lipid-lowering pharmaceutical preparation according to claim 1, characterized in that: its auxiliary materials include dextrin and sucrose.

[0042] The preparation method of the above-mentioned weight-loss and lipid-low...

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Abstract

The invention belongs to the technical field of biomedicine, and particularly relates to a weight-losing and lipid-lowering pharmaceutical preparation and a preparation method thereof. Active ingredients of the pharmaceutical preparation include anthraquinone compounds, flavonoid compounds and saponin compounds; the anthraquinone compounds include the total anthraquinone compounds in radix polygoni multiflori, semen cassiae and rhizoma polygoni cuspidati; the flavonoid compounds comprise the total flavonoid compounds in fructus crataegi, lotus leaf and pericarpium citri reticulatae; the saponin compounds comprise the total saponin compounds in radix astragali and spina gleditsiae. The pharmaceutical preparation has the advantages of small dosage and good effect. According to the preparation method, the active ingredients can be effectively extracted, and the method has the advantages of simple operation and short use time.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and in particular relates to a weight-loss and lipid-lowering medicinal preparation and a preparation method thereof. Background technique [0002] In recent years, with the improvement of people's living standards and changes in lifestyle, the proportion of obese people is increasing, and the incidence of hyperlipidemia has increased significantly. Atherosclerosis caused by hyperlipidemia is the main cause of coronary heart disease, hypertension and cerebrovascular disease. Research on weight-loss and lipid-lowering drugs or related health products has increasingly become a hot spot in medical research. At present, the clinical lipid-lowering drugs are still mainly western medicines, which have relatively large side effects and even acute toxicity events. [0003] Compared with western medicine, traditional Chinese medicine preparation has unique advantages. Its curative effect is definite...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/752A61K9/16A61P3/06A61P3/04
CPCA61K9/1605A61K36/481A61K36/482A61K36/483A61K36/62A61K36/704A61K36/734A61K36/752A61K2236/333A61K2236/39A61K2236/55A61K2300/00
Inventor 王占一
Owner ZAOZHUANG UNIV
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