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Oral care composition for children and application thereof to prevention of decayed teeth of children

An oral care and composition technology, which is applied in children's oral care composition and its application in children's dental caries prevention, can solve the problems that children are not recommended to use fluoride toothpaste, children are harmful to the body, and the teeth and bones are greatly affected. To achieve the effect of inhibiting the growth of cariogenic bacteria, resisting bacterial erosion, and reducing dental caries in children

Inactive Publication Date: 2018-07-13
太极娃生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although fluoride has been proved to have a very good anti-caries effect, but the fluoride content in the human body is too high, which has a greater impact on teeth and bones, especially children, whose swallowing function is not complete, and excessive intake of fluoride will have a negative impact on children's health. Harmful, so fluoride toothpaste is not recommended for children
[0007] There are many children's toothpastes on the market, but there is a problem that the age range is too wide and there is no targeted care. Therefore, the development of new care products for children's oral problems not only meets the needs of consumers, but also has a broad market space

Method used

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  • Oral care composition for children and application thereof to prevention of decayed teeth of children

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] The preparation of embodiment 1 oral cavity spray for children (the amount of each substance is by weight in the following formula)

[0020] Formula 1: Propylene Glycol 1%, Glycerin 0.5%, Polyoxyethylene Ricinoleate 0.5%, Macrogol 6000 1%, Xylitol 6%, Green Tea Extract 3%, Peppermint Extract 5%, Sodium Carbonate 5%, Sodium Bicarbonate 2% Sodium acetate 1% Calcium chloride 4% Methylparaben 1% Food flavor 0.5%, the balance is added to 100% with deionized water.

[0021] Formula 2: Propylene Glycol 1% Glycerin 0.5% Polyoxyethylene Ricinoleate 0.5%, Macrogol 6000 1% Xylitol 6% Peppermint Extract 5% Sodium Carbonate 5% Sodium Bicarbonate 2% Sodium Acetate 1% Chlorine Calcium 4% Methylparaben 1% food flavor 0.5%, the balance is added to 100% with deionized water.

[0022] Formula 3: Propylene Glycol 1% Glycerin 0.5% Polyoxyethylene Ricinoleate 0.5%, Macrogol 6000 1% Xylitol 6% Green Tea Extract 3% Sodium Carbonate 5% Sodium Bicarbonate 2% Sodium Acetate 1% Chlorine Calcium ...

Embodiment 2

[0025] The anti-caries experiment of embodiment 2 children's oral cavity spray

[0026] One, experimental sample: formula 1-5 of embodiment 1.

[0027] 2. Test method:

[0028] Fifty caries-free children aged 3-5 were selected and randomly divided into five groups according to sex and age, with 10 children in each group. The children in each group were respectively given the sprays of formula 1-5 three times a day, each time the nozzle was aimed at the oral cavity and sprayed for 2-3 times. After one year of follow-up, the occurrence of dental caries in 10 children in each group was recorded.

[0029]

[0030] It can be seen from the above follow-up experiment that formula 1 and formula 5 of the present invention can effectively prevent the occurrence of dental caries in children.

Embodiment 3

[0031] The antibacterial test of embodiment 3 children's mouth spray

[0032] In this embodiment, the five formulations in Example 1 are used as experimental samples to carry out antibacterial tests, specifically for cariogenic bacteria such as Streptococcus mutans, Lactobacillus, and Actinomycetes that are present in everyone's oral cavity.

[0033] The specific experimental method is to mix the five formula stock solutions of Example 1 with the pathogenic bacteria liquid in the logarithmic growth phase in equal amounts, and use the absorbance method to measure the pathogenic bacteria at 0h, 1.5h, 3h, 4.5h, 6h, and 7.5h respectively. The growth curve of the pathogen is represented by △OD. The smaller the △OD, the stronger the inhibitory effect.

[0034] From the results of OD inhibition, the antibacterial effect of formula 1 and formula 5 is much better than the effect of formula 2-4, showing obvious effect of inhibiting oral bacteria.

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Abstract

The invention provides an oral care composition for children. The oral care composition for children comprises a green tea extract and a mint extract. The green tea extract and mint extract each havea poor effect of preventing cariogenic bacteria such as streptococcus mutans, lactobacillus and actinomycetes in personal oral cavities; but when the green tea extract and the mint extract are used together, early childhood caries can be prevented effectively and occurrence of the early childhood caries can be obviously reduced.

Description

technical field [0001] The invention relates to the technical field of children's oral care, in particular to a children's oral care composition and its application in children's dental caries prevention. Background technique [0002] Children's oral problems are a big problem for children and their parents, the most common of which are tooth decay and periodontal disease. [0003] In daily life, due to children's lack of self-consciousness and understanding, they often like to eat snacks such as candy and biscuits, and their parents do not guide them well, many children have dental caries, pain and other oral diseases prematurely. Affect children's study, life and general health. Therefore, parents must educate children to pay attention to oral hygiene from an early age, and learn to develop a good habit of brushing teeth correctly, morning and evening. [0004] In addition, there are differences in the oral environment of children in the morning and evening. During the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/9789A61K8/20A61K8/34A61Q11/00
CPCA61K8/20A61K8/345A61K8/97A61Q11/00
Inventor 汪蕾
Owner 太极娃生物科技有限公司
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