Pharmaceutical composition having functions of relieving nerves and helping sleep and preparation method thereof

A technology for soothing nerves and composition, applied in the field of medicine, can solve the problem of not advocating long-term use, etc., and achieve the effects of improving curative effect, hypnotic effect, and soothing nerves

Pending Publication Date: 2018-09-07
YUNNAN HEMPSON BIO-TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Due to the possibility of dependence on some drugs, long-term use is generally not recommended

Method used

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  • Pharmaceutical composition having functions of relieving nerves and helping sleep and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] This embodiment provides a pharmaceutical composition with the functions of soothing nerves and helping sleep, which is mainly made of the following raw materials in parts by weight: 99 parts of industrial hemp extract, 1 part of Jujube seed extract, 80 parts of vegetable oil and preservatives 0.5 servings.

[0026] In this embodiment, the pharmaceutical composition with soothing nerves and sleep-aiding effects is made into a soft capsule, and its preparation method comprises the following steps:

[0027] S1. Select Yunnan industrial hemp flowers and / or leaves, dry until the water content is 13% lower, and pulverize to 50 mesh to obtain industrial hemp raw material powder;

[0028] S2. The industrial hemp raw material powder is extracted with supercritical carbon dioxide. The supercritical carbon dioxide extraction conditions are: pressure 11MPa, temperature 40°C, and entrainer 80% (v / v) ethanol to obtain the primary extract of industrial hemp;

[0029] S3. Extract the...

Embodiment 2

[0034] This embodiment provides a pharmaceutical composition with the functions of soothing nerves and helping sleep, which is mainly made of the following raw materials in parts by weight: 50 parts of industrial hemp extract, 50 parts of jujube seed extract, 40 parts of vegetable oil and preservatives 2 servings.

[0035] In this embodiment, the pharmaceutical composition with soothing nerves and sleep-aiding effects is made into a soft capsule, and its preparation method comprises the following steps:

[0036] S1. Select Yunnan industrial hemp flowers and / or leaves, dry to a moisture content lower than 13%, and pulverize to 200 mesh to obtain industrial hemp raw material powder;

[0037] S2. The industrial hemp raw material powder is extracted with supercritical carbon dioxide. The supercritical carbon dioxide extraction conditions are: pressure 9MPa, temperature 45°C, and entrainer 70% (v / v) ethanol to obtain the primary extract of industrial hemp;

[0038] S3. Extract the...

Embodiment 3

[0043]This embodiment provides a pharmaceutical composition with the functions of soothing nerves and helping sleep, which is mainly made of the following raw materials in parts by weight: 70 parts of industrial hemp extract, 24 parts of jujube seed extract, 70 parts of vegetable oil and preservatives 1.5 servings.

[0044] In this embodiment, the pharmaceutical composition with soothing nerves and sleep-aiding effects is made into a soft capsule, and its preparation method comprises the following steps:

[0045] S1. Select Yunnan industrial hemp flowers and / or leaves, dry until the water content is 13% lower, and pulverize to 100 mesh to obtain industrial hemp raw material powder;

[0046] S2. The industrial hemp raw material powder is extracted with supercritical carbon dioxide. The supercritical carbon dioxide extraction conditions are: pressure 13MPa, temperature 37°C, and entrainer 85% (v / v) ethanol to obtain the primary extract of industrial hemp;

[0047] S3. Extract t...

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Abstract

The invention belongs to the technical field of medicines, and particularly relates to a pharmaceutical composition having the functions of relieving nerves and helping sleep. The pharmaceutical composition is mainly prepared from, by weight, 50-99 parts of industrial hemp extract, 1-50 parts of spina date seed extract, 40-80 parts of vegetable oil and 0.5-2 parts of preservative. The pharmaceutical composition is made into a soft capsule, and the preparation method includes the steps that S1, Yunnan industrial hemp flowers and/or leaves are selected and pulverized to 50-200 mesh to obtain industrial hemp raw material powder; supercritical carbon dioxide extraction is adopted, and column chromatography is adopted for refining and detoxification to obtain the industrial hemp extract; S2, the spina date seeds are dried and pulverized to 50-100 mesh, and supercritical carbon dioxide extraction is adopted to obtain the spina date seed extract; S3, the industrial hemp extract, the spina date seed extract, the vegetable oil and the preservative are weighed by weight ratio, mixed, heated to 60-101 DEG C, stirred and mixed evenly to obtain contents of soft capsules to be made into the softcapsules. The pharmaceutical composition has the effects of relieving nerves and helping sleep.

Description

technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a pharmaceutical composition and preparation with functions of soothing nerves and helping sleep and a preparation method thereof. Background technique [0002] With the rapid development of society, people's work pressure and life pressure are increasing, resulting in many people's mental stress, palpitations, trance, restless sleep and eating, inability to have high-quality sleep, and even insomnia. Insomnia can cause fatigue, restlessness, general malaise, listlessness, sluggish response, headache, and inability to concentrate. In severe cases, it can lead to functional diseases such as schizophrenia, depression, anxiety, and autonomic dysfunction. [0003] Although there is a wide variety of hypnotic drugs, the primary use of most of them is not to treat insomnia. Current clinical treatments for insomnia mainly include benzodiazepines benzodiazepine receptor ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/725A61K9/48A61K47/44A61P25/20A61P25/00
CPCA61P25/00A61P25/20A61K9/4808A61K9/4858A61K36/185A61K36/725A61K2236/37A61K2300/00
Inventor 项伟顾文云
Owner YUNNAN HEMPSON BIO-TECH CO LTD
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