Nerve electrode and preparation method thereof

An electrode and nerve technology, applied in the field of new biomaterials, can solve the problems of non-uniform distribution and limited conductivity of conductive polymers, and achieve the effect of reducing contact resistance, having application value, and reducing costs.

Inactive Publication Date: 2018-09-28
INST OF ENVIRONMENTAL MEDICINE & OCCUPATIONAL MEDICINE ACAD OF MILITARY MEDICINE ACAD OF MILITARY SCI
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Problems solved by technology

Many studies have mixed conductive polymers (CP) into alginate gels to modify neural electrode materials through electropolymerization. The conductive polymers (CP) are only aggregat

Method used

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  • Nerve electrode and preparation method thereof
  • Nerve electrode and preparation method thereof
  • Nerve electrode and preparation method thereof

Examples

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[0019] Example 1:

[0020] Please refer to figure 1 , figure 2 , image 3 and Figure 4 , A method for preparing nerve electrodes, such as figure 1 As shown, the microwire electrode is electro-deposited with conductive polymer (CP) to form a conductive polymer (CP) coating, and then passes through alginic acid gel (Al) / multi-walled carbon nanotubes (CNT) / conductive polymer (CP) ) After electrodeposition, an alginic acid gel (Al) / multi-walled carbon nanotube (CNT) / conductive polymer (CP) coating is formed, and finally the conductive polymer (CP) in the gel is electropolymerized to form a conductive polymerization of point polymerization 物(CP) network.

[0021] The specific process is: preparing 100 mL of 0.1 wt% EDOT and 0.2 wt% PSS solutions, and ultrasonic treatment until the EDOT monomer is uniformly dispersed to prepare conductive polymer (CP) electroplating solution. 6mg / mL multi-walled carbon nanotubes (CNTs) are dispersed in PEDOT / PSS (1.3-1.7wt%) solution by ultrasound, ul...

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Abstract

The invention discloses a nerve electrode and a preparation method thereof. The nerve electrode comprises a substrate electrode. The invention particularly relates to nerve electrodes of an alginate gel (Al), a multi-walled carbon nanotube (CNT), and a conductive polymer (CP) and a preparation method thereof. The flexibility of the alginate gel (Al) and the conductivity of the conductive polymer (CP) are both achieved, the biocompatibility is good, and the nerve electrodes are closely combined with the substrate electrode. Therefore, according to the neural electrodes of the alginate gel (Al),the multi-walled carbon nanotube (CNT) and the conductive polymer (CP), the signal sensitivity and long term safety requirements of the nerve electrodes are met.

Description

technical field [0001] The invention belongs to the technical field of new biomaterials, and relates to a nerve electrode and a preparation method thereof, in particular to a nerve electrode made of alginate gel, multi-walled carbon nanotubes, and a conductive polymer and a preparation method thereof, and the modified nerve electrode It has good electrochemical performance and excellent biocompatibility. Background technique [0002] Nerve electrodes are used to record nerve action potentials and signal input. The contact interface between the signal recording site and the nerve tissue is a key factor affecting its performance. Due to the mismatch between the recording site and the physical and chemical properties of the nerve tissue, nerve tissue is often caused. Inflammatory response and electrode failure, nerve electrodes have technical bottlenecks in terms of signal sensitivity and long-term safety. It is urgent to develop new electrode modification materials to improve ...

Claims

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Application Information

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IPC IPC(8): A61B5/04H01B13/00
CPCA61B5/24H01B13/00
Inventor 王坤崔博王天辉杲修杰杨红莲佘晓俊
Owner INST OF ENVIRONMENTAL MEDICINE & OCCUPATIONAL MEDICINE ACAD OF MILITARY MEDICINE ACAD OF MILITARY SCI
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