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A method for preparing medicine for treating hypertension with Radix Paeoniae Alba and Dendrobium officinale

A Dendrobium candidum and high blood pressure technology, which is applied in the field of drug preparation, can solve problems such as the compatibility and use of traditional Chinese medicines, and achieve the effects of improving effectiveness, stabilizing liver yang, and improving antihypertensive curative effect

Active Publication Date: 2021-07-09
HANGZHOU DANHE PHARM CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In the use of traditional Chinese medicine, these two traditional Chinese medicines have never been used in combination

Method used

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  • A method for preparing medicine for treating hypertension with Radix Paeoniae Alba and Dendrobium officinale
  • A method for preparing medicine for treating hypertension with Radix Paeoniae Alba and Dendrobium officinale
  • A method for preparing medicine for treating hypertension with Radix Paeoniae Alba and Dendrobium officinale

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] Dendrobium officinale 8 parts, white peony 6 parts:

[0037] Take 400g of Dendrobium officinale and 300g of Radix Paeoniae Alba in accordance with the 2015 edition of "Chinese Pharmacopoeia".

[0038] Grind Radix Paeoniae Alba into powder, add 70% ethanol of 7 times the total crude drug amount, and extract under reflux for 1 hour, extract twice, and extract the residue with water after alcohol extraction;

[0039] The residue after alcohol extraction of Paeoniae Alba was extracted twice with water: the first water extraction: add 10 times the amount of crude drug in water, extract at 100°C for 1 hour; the second water extraction: add 10 times the total amount of crude drug in water, Extract at 100°C for 1 hour. The aqueous extracts were combined and concentrated. Combine Paeoniae Alba Alcoholic Extract and Water Extract.

[0040] Grinding Dendrobium officinale into powder, adding Dendrobium officinale powder to the combined extract of Paeoniae Alba and water, and add...

Embodiment 2

[0042] Dendrobium officinale 8 parts, white peony root 2 parts:

[0043] Take 400g of Dendrobium officinale and 100g of Radix Paeoniae Alba in accordance with the 2015 edition of "Chinese Pharmacopoeia".

[0044] Grind Radix Paeoniae Alba into powder, add 70% ethanol of 7 times the total crude drug amount, and extract under reflux for 1 hour, extract twice, and extract the residue with water after alcohol extraction;

[0045] The residue after alcohol extraction of Paeoniae Alba was extracted twice with water: the first water extraction: add 10 times the amount of crude drug in water, extract at 100°C for 1 hour; the second water extraction: add 10 times the total amount of crude drug in water, Extract at 100°C for 1 hour. The aqueous extracts were combined and concentrated. Combine Paeoniae Alba Alcoholic Extract and Water Extract.

[0046] Grinding Dendrobium officinale into powder, adding Dendrobium officinale powder to the combined extract of Paeoniae Alba and water, an...

Embodiment 3

[0048] Dendrobium officinale 8 parts, white peony root 32 parts:

[0049] Take 100g of Dendrobium officinale and 400g of Radix Paeoniae Alba in accordance with the 2015 edition of "Chinese Pharmacopoeia".

[0050] Grind Radix Paeoniae Alba into powder, add 70% ethanol of 7 times the total crude drug amount, and extract under reflux for 1 hour, extract twice, and extract the residue with water after alcohol extraction;

[0051] The residue after alcohol extraction of Paeoniae Alba was extracted twice with water: the first water extraction: add 10 times the amount of crude drug in water, extract at 100°C for 1 hour; the second water extraction: add 10 times the total amount of crude drug in water, Extract at 100°C for 1 hour. The aqueous extracts were combined and concentrated. Combine Paeoniae Alba Alcoholic Extract and Water Extract.

[0052] Grinding Dendrobium officinale into powder, adding Dendrobium officinale powder to the combined extract of Paeoniae Alba and water, a...

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Abstract

The invention relates to medicine preparation technology, and aims to provide a method for preparing medicine for treating hypertension with Radix Paeoniae Alba and Dendrobium officinale. It includes: grinding white peony root into powder, extracting with alcohol, extracting the residue after alcohol extraction with water, and combining the concentrated extract; grinding Dendrobium candidum into powder, adding it to the combined extract, and adding auxiliary materials to prepare it for treatment Medicines for high blood pressure. In the present invention, the extract of Paeoniae Alba and Dendrobium officinale powder has outstanding curative effect on treating hypertension, and its antihypertensive effect can exceed that of western medicine irbesartan. Compared with conventional water extraction, the double extraction method of white peony alcohol reduces the loss of components and improves the effectiveness, promotes the complete utilization of white peony oral treatment by the human body, and improves the curative effect. It has a selective adjustment effect on hypertensive patients and has no effect on normal blood pressure: it has the effect of lowering blood pressure on hypertensive patients, but has no effect on normal blood pressure, and will not reduce high blood pressure below normal. This is also an advantage over most western antihypertensive drugs.

Description

technical field [0001] The invention relates to medicine preparation technology, in particular to a method for preparing medicine for treating hypertension with white peony root and dendrobium officinale. Background technique [0002] Hypertension is a common high incidence clinically, which has serious harm to the heart, brain, kidney and other important organs. Western medicine treatment of hypertension still lacks the medicine for adjusting body constitution and can adjust blood pressure (depressor). The antihypertensive treatment of modern medicine is all symptomatic treatment. Currently commonly used antihypertensive drugs include calcium channel blockers (CCBs), angiotensin-converting enzyme inhibitors (ACEIs), angiotensin II receptor blockers (ARBs), diuretics, and β-blockers. , still can not completely prevent the progression of hypertension and its secondary lesions. Most hypertensive patients need two or more antihypertensive drugs to reach the target blood pres...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/8984A61P9/12A23L33/10
CPCA23V2002/00A23L33/10A23L33/105A23V2200/326A23V2300/14A23V2250/21
Inventor 吴人照吴悦陈宇
Owner HANGZHOU DANHE PHARM CO LTD
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