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30results about How to "Stable curative effect" patented technology

Formula of traditional Chinese medicine for treating diabetic nephropathy

The invention discloses a formula of a traditional Chinese medicine for treating diabetic nephropathy. The formula is characterized by involving the following raw materials by weight: 6 parts of astragalus roots, 3 parts of Pseudostellaria heterophylla, 2 parts of angelica, 2 parts of radix rehmanniae, 2 parts of cornus officinalis, 2 parts of Salvia miltiorrhiza, 3 parts of raw coix seeds, 2 parts of earthworm, 2 parts of Poria, and 2 parts of rhizoma alismatis. Directed at qi-yin deficiency, i.e. the traditional Chinese medicinal core pathogenesis of diabetic nephropathy, the formula has the efficacy of supplementing Qi and nourishing Yin, dispersing blood stasis and promoting dieresis, and is suitable for different-stage diabetic nephropathy with the main manifestations of soreness and weakness of waist and knees, weakness all over the body, edema, foaming urine, nausea, skin pruritus, limb numbness or acroanesthesia (or chilling), dark red tongue, thin or greasy tongue coat, thin pulse or rapid pulse and the like. The formula involves simple medicines and can achieve a special effect. Previous long-term clinical practice and scientific research prove that the formula can significantly reduce the urinary protein excretion rate, delay the renal function progress, effectively improve glucolipid metabolism, effectively control blood pressure, improve the quality of life of patients, and greatly decrease kidney disease end point events, and has the advantages of stable long-term effect and good safety.
Owner:张宁

Preparation method of ilicin A and total triterpenoids contained in Hainan holly leaf and application of ilicin A and total triterpenoids

The invention relates to a method for extracting total triterpenoids and monomer ilicin A of enriched Hainan holly leaf. The method is characterized by comprising the following extraction steps that raw materials of Hainan holly leaf is subjected to reflux extraction by 50 percent to 95 percent of ethanol, liquid supernatant and a precipitation part are obtained after the extraction liquid is concentrated and centrifuged, the precipitation part is subjected to mixed suspension by 30 percent to 40 percent of ethanol, then, petroleum ether is used for extraction, the lower layer solution is subjected to pressure reduction, concentration and drying to obtain total triterpenoids; in addition, the ethanol extraction liquid is subjected to pressure reduction, recovery and evaporation to dryness, water is used for dissolving, acid is added for hydrolysis, organic solvents are extracted, the recovery to dryness, the silicagel column coating and the sherwood oil-ethyl acetate gradient elution are carried out, eluant is collected, elution solvents are recovered through pressure reduction, and the monomer ilicin A is obtained. According to an extraction enriching method, the total triterpenoids content of the obtained product exceeds 50 percent, the purity of the monomer ilicin A is high, meanwhile, the repeatability and the stability of the method are good, the transfer rate of effective ingredients of the raw material is high, the cost is low, the operation is simple and convenient, and the method is suitable for industrial production. Meanwhile, the invention also relates to application of the total triterpenoids and the monomer ilicin A of Hainan holly leaf in the cardiovascular disease treating aspect, in particular to the atherosclerosis aspect, and the potential development value is realized.
Owner:CHINA PHARM UNIV

Application method of radix paeoniae alba and caulis dendrobii officinalis to preparation of antihypertensive drug

The invention relates to a drug preparation technology, and aims to provide an application method of radix paeoniae alba and herba dendrobii officinalis to preparation of an antihypertensive drug. Theapplication method comprises the following steps: grinding radix paeoniae alba into powder, performing alcohol extraction on the radix paeoniae alba powder, extracting residual water left after the alcohol extraction, and combining concentrated extracting solutions; grinding the caulis dendrobii officinalis into powder, adding the caulis dendrobii officinalis powder into the combined extracting solution, and adding accessories to obtain the antihypertensive drug. A combination of an extract prepared by alcohol extraction and water extraction of the radix paeoniae alba and the caulis dendrobiiofficinalis powder has an outstanding curative effect on hypertension, and has an antihypertensive effect which can exceed a western medicine of irbesartan. Compared with conventional water extraction, the alcohol-water extraction method for the radix paeoniae alba has the advantages that component loss is reduced, the effectiveness is improved, complete utilization of oral radix paeoniae alba byhuman body is facilitated, and the curative effect is improved. Compared with most western antihypertensive drugs, the antihypertensive drug has a selective regulating effect on people with high blood pressure without influencing normal blood pressure: the antihypertensive drug can lower high blood pressure, but do not lower normal blood pressure or lower the high blood pressure below normal level.
Owner:HANGZHOU DANHE PHARM CO LTD

Vulnerary hemostatic and preparation technology thereof

The invention discloses a vulnerary hemostatic and a preparation process thereof. The vulnerary hemostatic comprises the raw Chinese medicinal herbs as main medicaments by weight: 20-40 parts of baeckea frutescens, 10-30 parts of big-leaf beautyberry leaf, 10- 30 parts of ageratum conyzoides, 10-30 parts of hairyvein agrimony, 10-30 parts of teucrium viscidum, and 10-30 parts of herba cirsii japonica, which are mainly used for stopping bleeding and relieving pain; straw, red psychotria leaf, false China tree and lemon-scented gum leaf capable of diminishing inflammation and promoting tissue regeneration can be used as auxiliary medicaments; adhatoda ventricosa, common gendarussa herb and glechoma biondiana with the functions of removing blood stasis, promoting tissue regeneration and promoting blood circulation to remove meridian obstruction are used as assistant; and through reasonable combination, the pharmacological functions of stopping bleeding, relieving pain, diminishing inflammation, removing blood stasis, promoting tissue regeneration and promoting blood circulation to remove meridian obstruction are realized, and the aims of quickly treating wound and stopping bleeding are fulfilled. According to the vulnerary hemostatic preparation process, the finished product is prepared by the processes of crushing, sieving, drying, stirring and the like; and the original effects of the medicaments are preserved, the properties of the medicaments are not affected because the medicaments are not chemically processed, and the obtained finished product has a stable treatment effect. The vulnerary hemostatic has the characteristics of high hemostatic speed, low cost, good effects of diminishing inflammation, relieving pain and promoting tissue regeneration, no toxic or side effect, convenience in use, convenience in collection of raw medicinal herbs and easiness for popularization and application.
Owner:龙家芳

Oral Chinese traditional medicine composition for treating chronic enteritis

The present invention discloses a traditional Chinese medicine composition for treating chronic enteritis by internal administration, which pertains to the field of traditional Chinese medicine. The parts by weight of the pharmaceutical raw materials to make the active ingredients of the traditional Chinese medicine composition for treating chronic enteritis by internal administration are: 15 parts of pilose Asiabell root, 10 parts of stir-fried largehead atractylodes rhizome, 15 parts of roasted membranous milkvetch root, 30 parts of halloysit, 24 parts of stir-fried coix seed, 10 parts of divaricate saposhnikovia root, 10 parts of roasted costustoot, 6 parts of roasted largetrifoliolious bugbane rhizome, 3 parts of catechu, 15 parts of yanhusuo, 15 parts of stir-fried dark plum fruit, 10 parts of Indian buead and 3 parts of golden thread. The water is used for boiling or the medicines are ground into the powder, and then the present invention is taken after mixing with the warm water. The medicine composition of the present invention can have the synergistic effect of the efficacy and achieve the effects of tonifying spleen, coordinating intestines, astringing and stopping diarrhea. The traditional Chinese medicine composition for treating chronic enteritis by internal administration achieves the significant effect, stable efficacy and no toxicity or side effects in the treatment of chronic enteritis. The clinical verification of about 100 cases proves that the effective rate can achieve 100 percent.
Owner:孙元萍

Divalproex sodium sustained-release agent composition and preparation method thereof

The invention provides a divalproex sodium sustained-release agent composition. The composition comprises divalproex sodium accounting for 60 to 80% of the total weight of the composition, a sustained-release material accounting for 10 to 39% of the total weight of the composition and a lubricating agent accounting for 1 to 10% of the total weight of the composition, wherein the sustained-release material is one selected from the group consisting of stearic acid, hydrogenated castor oil, glyceryl behenate, palm wax and mixtures of the above-mentioned substances, and the lubricating agent is one selected from the group consisting of magnesium stearate, silica, talcum powder and mixtures of the above-mentioned substances. The invention also provides a preparation method for the divalproex sodium sustained-release agent composition. The composition is simple in formula, needs no accessory materials like a binder and a disintegrating agent essential in conventional preparation production and provides a sustained-release preparation with stable curative effect, long-lasting action and convenience in administration for clinical practice. Compared with the prior art, the invention has the following advantages: the preparation method for a divalproex sodium sustained-release tablet is simple and effective and can be easily scaled-up.
Owner:JS INNOPHARM (SHANGHAI) LTD

Medicine composition for treating diarrhea as well as preparation method and application thereof

The invention belongs to the field of medicines, and particularly relates to a medicine composition for treating diarrhea as well as a preparation method and application thereof. The technical problem to be solved by the invention is to provide the new medicine composition. The new medicine composition comprises the following medicinal raw materials in parts by weight; 1-3 parts of ephedra, 1-4 parts of radix peucedani and 2.5-4.5 parts of semen plantaginis. The purpose of treating or improving diarrhea can be realized by the method. For the convenience of application and the simpleness and convenience of preparations, the medicine composition is prepared into decoction for use by an inventor. The medicine composition is used for clearing damp and stopping diarrhea, is suitable for treatment of diarrhea of children aged 0 to 12 years and can also be taken by adults. The medicine composition can be used for treating various types of diarrheas and is particularly suitable for gastrointestinal type cold and simple diarrhea and chronic diarrhea of children; and more than 10 years of clinical application observation proves that more than 300 of diarrhea patents are treated, and the recovery rate is above 95%. The medicine composition can also be used for treating cold and relieving a cough, treats more than 200 of patients suffering from cold and cold and has the recovery rate of above 85%.
Owner:屈友初

Application of kidney-tonifying and brain-benefiting preparation in preparation of medicine for treating infantile cerebral palsy

The invention discloses an application of a kidney-tonifying and brain-benefiting preparation in preparation of a medicine for treating infantile cerebral palsy. The kidney-tonifying and brain-benefiting preparation comprises the following components in parts by weight: 30-80 parts of red ginseng, 4-12 parts of cornu cervi pantotrichum, 30-80 parts of fried spina date seeds; 80-120 parts of prepared rehmannia roots, 30-80 parts of poria cocos, 25-55 parts of radix scrophulariae, 30-80 parts of honey-stir-baked polygala roots, 30-80 parts of radix ophiopogonis, 25-55 parts of schisandra chinensis, 30-80 parts of angelica sinensis, 25-55 parts of Sichuan lovage rhizomes, 25-55 parts of radix achyranthis bidentatae, 30-80 parts of fried Chinese yams, 25-55 parts of salt-processed fructus psoraleae, 25-55 parts of Chinese wolfberry fruits and 8-18 parts of cinnabar. The kidney-tonifying and brain-benefiting preparation has an exact effect of treating infantile cerebral palsy, can relieve pains of children patients, promotes liver, kidney, spleen and stomach function repair and function recovery of the children patients, and promotes brain development and recovery of the children patients.
Owner:GUANGDONG LUOFUSHAN SINOPHARM

Anderson's disease and therapeutic drug thereof

The invention relates to Anderson's disease and a therapeutic drug thereof, belongs to the technical field of medicine, and aims to solve the problem of difficulty in Anderson's disease treatment. According to analysis, the Anderson's disease is caused by congenital deficiency, liver-kidney yin deficiency and phlegm-caused meridian obstruction, and patients shall take the therapeutic drug, which comprises traditional Chinese medicinal herbs with effects of clearing liver, promoting blood circulation, tonifying spleen and qi, dispelling the wind, reducing phlegm, and activating channels and collaterals, to treat the Anderson's disease. The therapeutic drug comprises, by weight, 15 parts of radix sileris, 15 parts of sealwort, 15 parts of epimedium, 15 parts of turtle shells, 15 parts of the root bark of the peony tree, 15 parts of dried rehmannia roots, 15 parts of cistanche, 15 parts of lalang grass rhizomes, 15 parts of safflowers, 15 parts of houttuynia cordata, 15 parts of dried tangerine or orange peels, 10 parts of ginger, 15 parts of chrysanthemums, 10 parts of fried semen strychni and 8 parts of liquorice. The therapeutic drug has the advantages that stable curative effect is achieved, a positive theoretical solution for treating the Anderson's disease by traditional Chinese medicine is put forward, and the patients can rebuild their confident lives.
Owner:吕小萍
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