Formula of traditional Chinese medicine for treating diabetic nephropathy

A technology for diabetic nephropathy and traditional Chinese medicine, which is applied in pharmaceutical formulations, urinary system diseases, and medical preparations containing active ingredients, etc., can solve the problems of insignificant results, achieve excellent clinical efficacy, delay the progress of renal function, and reduce urinary protein excretion. rate effect

Inactive Publication Date: 2014-04-23
张宁
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  • Abstract
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  • Application Information

AI Technical Summary

Problems solved by technology

In terms of Western medicine treatment, there is currently a lack of specific drugs, and symptomatic treatments such as hypoglycemic, hypotensive, lipid-lowering, reasonable diet, and use of angiotensin-converting enzyme inhibitors (ACEI) or angiotensin receptor antagonists (ARB) to reduce proteinuria are still used. Mainly, but the effect is not significant

Method used

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Effect test

Embodiment Construction

[0010] (1) Add about 1600ml of cold water to soak the Chinese medicine formula raw material medical material of the present invention, not less than 30min;

[0011] (2) The first decoction: boil on high heat first, then change to low heat and continue decocting for about 40 minutes. During the decoction process, stir the medicinal materials 2-3 times, and filter the medicinal liquid (the first decoction generally takes about 200ml of medicinal liquid);

[0012] (3) The second decoction: add 1000ml of water to the dregs of the medicine, boil on high heat, then change to low heat and continue to decoct for 30 minutes, and filter the medicinal liquid (the second decoction generally takes about 150-200ml of medicinal liquid);

[0013] (4) Combine the two decoctions, the total decoction is about 350-400ml.

[0014] Dosage: 1 dose per day, orally twice in the morning and evening, 175-200ml each time.

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Abstract

The invention discloses a formula of a traditional Chinese medicine for treating diabetic nephropathy. The formula is characterized by involving the following raw materials by weight: 6 parts of astragalus roots, 3 parts of Pseudostellaria heterophylla, 2 parts of angelica, 2 parts of radix rehmanniae, 2 parts of cornus officinalis, 2 parts of Salvia miltiorrhiza, 3 parts of raw coix seeds, 2 parts of earthworm, 2 parts of Poria, and 2 parts of rhizoma alismatis. Directed at qi-yin deficiency, i.e. the traditional Chinese medicinal core pathogenesis of diabetic nephropathy, the formula has the efficacy of supplementing Qi and nourishing Yin, dispersing blood stasis and promoting dieresis, and is suitable for different-stage diabetic nephropathy with the main manifestations of soreness and weakness of waist and knees, weakness all over the body, edema, foaming urine, nausea, skin pruritus, limb numbness or acroanesthesia (or chilling), dark red tongue, thin or greasy tongue coat, thin pulse or rapid pulse and the like. The formula involves simple medicines and can achieve a special effect. Previous long-term clinical practice and scientific research prove that the formula can significantly reduce the urinary protein excretion rate, delay the renal function progress, effectively improve glucolipid metabolism, effectively control blood pressure, improve the quality of life of patients, and greatly decrease kidney disease end point events, and has the advantages of stable long-term effect and good safety.

Description

technical field [0001] The invention belongs to the technical field of clinical treatment of traditional Chinese medicine, in particular to a traditional Chinese medicine formula for treating diabetic nephropathy. Background technique [0002] Diabetic nephropathy (DN) is one of the most serious and common chronic complications of diabetes. The World Health Organization predicts that the number of people with diabetes will exceed 48 million in 2030, with the resultant increase in the number of people with diabetic kidney disease. Diabetic nephropathy is the number one cause of chronic renal failure, accounting for about 40% of patients with end-stage renal failure. Once a patient develops microalbuminuria, renal damage develops rapidly, and most patients enter end-stage renal disease (ESRD) within a relatively short period of time, which will bring a heavy economic burden to individuals, families, and society, and the quality of life will also decrease. Seriously down. In...

Claims

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Application Information

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IPC IPC(8): A61K36/8994A61P3/10A61P13/12A61K35/56A61K35/62
Inventor 张宁
Owner 张宁
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