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Application of kidney-tonifying and brain-benefiting preparation in preparation of medicine for treating infantile cerebral palsy

A brain-enhancing preparation, a technology for children with cerebral palsy, which can be used in drug combinations, pharmaceutical formulations, plant raw materials, etc., can solve problems such as abnormal posture and reflexes, expensive treatment costs, and inability to completely cure them. Brain development and recovery, the effect of alleviating pain in children

Pending Publication Date: 2020-04-28
GUANGDONG LUOFUSHAN SINOPHARM
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Cerebral palsy in children (cerebral palsy), also known as cerebral palsy in children, commonly known as cerebral palsy, is a non-progressive brain injury syndrome caused by various reasons from before birth to within 1 month after birth. The lesion is in the brain and involves the limbs. The main manifestations are central movement disorders, abnormal muscle tone, abnormal posture and reflexes, and may be accompanied by epilepsy, mental retardation, language impairment, visual and auditory impairment, etc. The rate of children with cerebral palsy has a rising trend; the movement disorder of children with cerebral palsy is the key problem that causes injury and disability and affects physical development, self-care of life, and return to society. One, traditional Chinese medicine generally divides children with cerebral palsy into four types: strong liver and weak spleen, deficiency of both spleen and kidney, deficiency of liver and kidney, and obstruction of collaterals by phlegm and blood stasis, which correspond to spastic type, ataxia type, and arrhythmia of hands and feet in Western medicine. Dynamic type and ankylosing type, among which spastic type and athetoid type account for about 90% of the total. At present, the disease cannot be cured. The treatment is mainly rehabilitation training, medicine and traditional Chinese medicine, but the curative effect is not exact , cannot be completely cured, and the treatment is expensive

Method used

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  • Application of kidney-tonifying and brain-benefiting preparation in preparation of medicine for treating infantile cerebral palsy

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0026] This example discloses the application of kidney-tonifying and brain-tonifying preparations in the preparation of medicines for treating children with cerebral palsy. 80 parts of Huang, 30 parts of Poria cocos, 25 parts of Scrophulariaceae, 30 parts of honey polygala, 30 parts of Ophiopogon japonicus, 25 parts of Schisandra chinensis, 30 parts of angelica, 25 parts of Chuanxiong, 25 parts of Achyranthes bidentata, 30 parts of fried yam, 25 parts of salt psoralen 25 parts of medlar, 8 parts of cinnabar.

[0027] The dosage form of the medicine is a tablet, and the kidney-tonifying and brain-tonifying tablet is prepared by the following method:

[0028] S1. Prepare raw materials according to the ratio of each component of the formula;

[0029] S2. Extract volatile oil from schisandra chinensis, salt psoraleae, chuanxiong and angelica, and filter the extract for later use; add 60% ethanol to the dregs and heat and reflux to extract for 2 hours, filter, add 80% ethanol to ...

Embodiment 2

[0033] This example discloses the application of kidney-tonifying and brain-tonifying preparations in the preparation of medicines for treating children with cerebral palsy. 120 parts of Huang, 80 parts of Poria cocos, 55 parts of Scrophulariaceae, 80 parts of honey polygala, 80 parts of Ophiopogon japonicus, 55 parts of Schisandra chinensis, 80 parts of angelica, 55 parts of Chuanxiong, 55 parts of Achyranthes bidentata, 80 parts of fried yam, 55 parts of salt psoralen 55 parts of medlar, 18 parts of cinnabar.

[0034] The dosage form of the medicine is granule, and the kidney-tonifying and brain-tonifying granule is prepared by the following method:

[0035] S1. Prepare raw materials according to the ratio of each component of the formula;

[0036] S2. Extract volatile oil from schisandra chinensis, salt psoraleae, chuanxiong and angelica, and filter the extract for later use; add 60% ethanol to the dregs and extract by heating under reflux for 3 hours, filter, add 80% etha...

Embodiment 3

[0040] This example discloses the application of kidney-tonifying and brain-tonifying preparations in the preparation of medicines for treating children with cerebral palsy. 103 parts of Huang, 48 parts of Poria cocos, 37 parts of Scrophulariaceae, 48 parts of honey polygala, 48 parts of Ophiopogon japonicus, 37 parts of Schisandra chinensis, 48 ​​parts of angelica, 37 parts of Chuanxiong, 37 parts of Achyranthes bidentata, 48 parts of fried yam, 37 parts of salt psoralen 39 parts of medlar, 13 parts of cinnabar.

[0041] The dosage form of the medicine is a capsule, and the kidney-tonifying and brain-tonifying capsule is prepared by the following method:

[0042] S1. Prepare raw materials according to the ratio of each component of the formula;

[0043] S2. Extract volatile oil from schisandra chinensis, salt psoraleae, chuanxiong and angelica, and filter the extract for later use; add 60% ethanol to the dregs and extract by heating under reflux for 3 hours, filter, add 80% ...

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Abstract

The invention discloses an application of a kidney-tonifying and brain-benefiting preparation in preparation of a medicine for treating infantile cerebral palsy. The kidney-tonifying and brain-benefiting preparation comprises the following components in parts by weight: 30-80 parts of red ginseng, 4-12 parts of cornu cervi pantotrichum, 30-80 parts of fried spina date seeds; 80-120 parts of prepared rehmannia roots, 30-80 parts of poria cocos, 25-55 parts of radix scrophulariae, 30-80 parts of honey-stir-baked polygala roots, 30-80 parts of radix ophiopogonis, 25-55 parts of schisandra chinensis, 30-80 parts of angelica sinensis, 25-55 parts of Sichuan lovage rhizomes, 25-55 parts of radix achyranthis bidentatae, 30-80 parts of fried Chinese yams, 25-55 parts of salt-processed fructus psoraleae, 25-55 parts of Chinese wolfberry fruits and 8-18 parts of cinnabar. The kidney-tonifying and brain-benefiting preparation has an exact effect of treating infantile cerebral palsy, can relieve pains of children patients, promotes liver, kidney, spleen and stomach function repair and function recovery of the children patients, and promotes brain development and recovery of the children patients.

Description

technical field [0001] The invention relates to the technical field of new applications of Chinese patent medicines, in particular to the application of kidney-tonifying and brain-tonifying preparations in the preparation of medicines for treating children with cerebral palsy. Background technique [0002] Cerebral palsy in children (cerebral palsy), also known as cerebral palsy in children, commonly known as cerebral palsy, is a non-progressive brain injury syndrome caused by various reasons from before birth to within 1 month after birth. The lesion is in the brain and involves the limbs. The main manifestations are central movement disorders, abnormal muscle tone, abnormal posture and reflexes, and may be accompanied by epilepsy, mental retardation, language impairment, visual and auditory impairment, etc. The rate of children with cerebral palsy has a rising trend; the movement disorder of children with cerebral palsy is the key problem that causes injury and disability ...

Claims

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Application Information

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IPC IPC(8): A61K36/8968A61P25/00A61K33/28A61K35/32
CPCA61K36/258A61K35/32A61K36/725A61K36/804A61K36/076A61K36/808A61K36/69A61K36/8968A61K36/79A61K36/57A61K36/232A61K36/236A61K36/21A61K36/8945A61K36/487A61K36/815A61K33/28A61P25/00A61K2236/331A61K2236/39A61K2236/333A61K2300/00
Inventor 滕云霞廖志钟梁银友
Owner GUANGDONG LUOFUSHAN SINOPHARM
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