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Application of botulinum toxin A to resistance of depression

A botulinum toxin type A and antidepressant technology, which is applied in the field of medicine and achieves the effects of stable curative effect, few operation steps and small effect.

Inactive Publication Date: 2018-06-01
THE SECOND HOSPITAL AFFILIATED TO SUZHOU UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Botulinum toxin type A used in the treatment of depression has no precedent

Method used

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  • Application of botulinum toxin A to resistance of depression
  • Application of botulinum toxin A to resistance of depression
  • Application of botulinum toxin A to resistance of depression

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Experimental program
Comparison scheme
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Embodiment Construction

[0023] The present invention will be further described below in conjunction with embodiment, but protection scope of the present invention is not limited to this:

[0024] A type A botulinum toxin is used in antidepressant application, and the type A botulinum toxin is used for increasing brain-derived neurotrophic factor (BDNF).

[0025] The invention relates to an application of type A botulinum toxin in antidepressant, and the type A botulinum toxin is used for preparing antidepressant products.

[0026] The type A botulinum toxin is prepared into any clinically or pharmaceutically acceptable dosage form after adding auxiliary materials.

[0027] The dosage form is powder, tablet, capsule, dropping pill or injection.

[0028] The auxiliary materials are sucrose, dextran and gelatin.

[0029] The therapeutic effect of botulinum toxin type A in the treatment of depression

[0030] Table 1

[0031] Influencing factors of enrolled cases ([Mean(SEM)])

[0032]

[0033] L...

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Abstract

The invention discloses an application of botulinum toxin A to resistance of depression, and belongs to the field of medical technology. The botulinum toxin A is used for preparing an antidepressant product. The botulinum toxin A can be used for effectively controlling and treating depression, and compared with chemically synthesized medicaments, the effects of the technical scheme are smaller andcurative effects are stable. The technical scheme has simple technology and few operation steps, and is suitable for production of industrialization scale.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to an application of botulinum toxin type A in antidepressant, especially for increasing brain-derived neurotrophic factor (BDNF). Background technique [0002] Depression is one of the most common mental illnesses and a major accompanying symptom of other illnesses. The high suicide rate, high self-harm rate, and high recurrence rate of depression determine that depression is a serious social health problem. According to the report of the World Health Organization, as of 2012, there are estimated to be more than 350 million patients with depression worldwide. According to the epidemiological data published in "Nature" in 2014, the prevalence of depression in my country is 3.02%. Today's fast-paced, high-pressure lifestyle makes depression a high-risk disease with an increasing incidence year by year. The clinical core symptoms of depression mainly include: 1) "Three...

Claims

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Application Information

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IPC IPC(8): A61K38/48A61P25/24
CPCA61K38/48C12Y304/00
Inventor 罗蔚锋刘通李阳刘春风
Owner THE SECOND HOSPITAL AFFILIATED TO SUZHOU UNIV