External application bamboo cape jasmine five-yellow liquid for treating damaged skin tissues and applications thereof
A technology of Zhuzhi Wuhuang liquid and skin, which is applied in the direction of skin diseases, drug combinations, antipyretics, etc., and can solve problems such as skin tissue damage without application
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[0035] An externally administered Zhuzhiwuhuang liquid for treating damaged skin tissue, comprising the following preparation process:
[0036] Step 1: Add 9 parts of Coptis Rhizoma, 6 parts of Phellodendron Phellodendri, 6 parts of Scutellaria baicalensis, 9 parts of Jiaozhizi, 24 parts of Bamboo Leaf, and 9 parts of Glauber's Salt with water for liquid extraction. Add 13 times the amount of water for the first time, extract for 30 minutes, and extract for the second time Add 10 times the amount of water for the third time, extract for 30 minutes, combine the filtrates extracted three times, and concentrate;
[0037] Step 2: Add 0.36 parts of borneol, add 9 times the amount of 95% ethanol to dissolve, add 3 times the amount of Tween to aid dissolution, mix with the concentrated solution in step 1, and then add distilled water;
[0038] Step 3: Stand still for 24 hours;
[0039] Step 4: subpackage and sterilize the filtrate, and perform quality control;
[0040] Step 5: The ...
experiment example 1
[0075] Experimental example 1: The impact test of Zhuzhiwuhuang liquid of the present invention on mouse ear swelling caused by xylene
[0076] 60 KM mice, male, were randomly divided into 6 groups according to body weight, respectively, model control group (distilled water), vehicle control group (Zhuzhiwuhuang liquid vehicle control group), positive control group (distilled water). Semiasone ointment), high-dose experimental group (2-fold concentrated solution of Zhuzhi Wuhuang Liquid), medium-dose experimental group (Zhuzhi Wuhuang Liquid), and low-dose experimental group (double dilution of Zhuzhi Wuhuang Liquid). Remove the hair from the abdomen of all animals to form a 1.5cm×1.5cm hair removal administration area, and locally administer the corresponding test substance or reference substance in the hair removal area at 0.2ml (g) per animal, once a day, for 3 consecutive days; 40 minutes after the medicine, smear 30ul of xylene on both sides of the right ear of the mouse,...
experiment example 2
[0081] Experimental Example 2: Effect test of Zhuzhi Wuhuang Liquid of the present invention on rat paw swelling caused by egg white
[0082]60 SD rats, male, measured the volume of the left paw, and stratified and randomly divided them into 6 groups, respectively, the model control group (distilled water), the vehicle control group (Zhuzhiwuhuang liquid solvent solution), the positive Control group (dexamethasone ointment), high-dose experimental group (2 times concentrated solution of Zhuzhi Wuhuang Liquid), medium-dose experimental group (Zhuzhi Wuhuang Liquid), low-dose experimental group (double dilution of Zhuzhi Wuhuang Liquid) . Smear the rat's left foot with the corresponding test product or reference product, and the dosage is 0.5ml (g) / rat, once a day, for 3 consecutive days. On the 3rd day, the volume of the left paw of the rat was measured twice, and the average value was used as the base volume; administration was administered after the measurement, and 10% fres...
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