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Traditional Chinese medicine composition used for preventing and treating ischemia reperfusion injury

A technology of ischemia-reperfusion and composition, which is applied in the direction of drug combination, pharmaceutical formula, plant raw materials, etc., can solve the problems of damaged oxygen free radicals of vascular endothelial cells, unfavorable health of human tissue, etc., and achieve the effect of improving absorption efficiency

Inactive Publication Date: 2018-12-18
朱鹏飞
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] This invention can effectively promote blood circulation and remove blood stasis, diuresis and dredge internal organs, and is suitable for acute and recovery periods of ischemic stroke. However, ischemia-reperfusion injury often causes damage to vascular endothelial cells, and at the same time, metabolic disorders can cause oxygen freedom. Explosive generation and accumulation of bases, and then have serious consequences that are not conducive to the health of human tissues

Method used

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  • Traditional Chinese medicine composition used for preventing and treating ischemia reperfusion injury

Examples

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Effect test

Embodiment 1

[0025] A traditional Chinese medicine composition for preventing ischemia-reperfusion injury, comprising the following raw materials in parts by weight: 13 parts of rhubarb, 33 parts of Glauber's salt, 27 parts of Magnolia officinalis, 17 parts of Citrus aurantium, 18 parts of Radix Paeoniae Rubra, fried radish seeds 25 parts, 20 parts of woody fragrance, 10 parts of fried peach kernel, 10 parts of salvia miltiorrhiza, 14 parts of poria cocos, 20 parts of astragalus.

[0026] The preparation method of the above-mentioned traditional Chinese medicine composition for preventing ischemia-reperfusion injury comprises the following steps:

[0027] (1) Take rhubarb, Magnolia officinalis, Citrus aurantium, Radix Paeoniae Rubra, fried radish seeds, woody incense, fried peach kernels, salvia miltiorrhiza, and Poria cocos in the grinder according to the parts by weight, and fully grind them into powder, add Glauber's salt and grind for 50 minutes, pass 400 mesh sieve to obtain refined m...

Embodiment 2

[0031] A traditional Chinese medicine composition for preventing ischemia-reperfusion injury, comprising the following raw materials in parts by weight: 17 parts of rhubarb, 28 parts of Glauber's salt, 35 parts of Magnolia officinalis, 12 parts of Citrus aurantium, 12 parts of Radix Paeoniae Rubra, fried radish seeds 35 parts, 10 parts of muxiang, 15 parts of fried peach kernel, 13 parts of salvia miltiorrhiza, 9 parts of poria cocos, 30 parts of astragalus.

[0032] The preparation method of the above-mentioned traditional Chinese medicine composition for preventing ischemia-reperfusion injury comprises the following steps:

[0033] (1) Put rhubarb, Magnolia officinalis officinalis, Fructus Citrus Fructus Citrus Fructus Citrus Fructus Citrus Fructus Auratus, Radix Paeoniae Rubra, Fried Raisin Seeds, Muxiang, Fried Peach Kernels, Salvia Miltiorrhiza, and Poria Cocos into a grinder according to parts by weight, and grind them fully into powder, add Glauber’s salt and grind for 4...

Embodiment 3

[0037] A traditional Chinese medicine composition for preventing ischemia-reperfusion injury, comprising the following raw materials in parts by weight: 16 parts of rhubarb, 29 parts of Glauber's salt, 28 parts of Magnolia officinalis, 16 parts of Citrus aurantium, 14 parts of Radix Paeoniae Rubra, fried radish 33 parts, 12 parts of woody fragrance, 14 parts of fried peach kernel, 11 parts of salvia miltiorrhiza, 12 parts of poria cocos, 28 parts of astragalus.

[0038] The preparation method of the above-mentioned traditional Chinese medicine composition for preventing ischemia-reperfusion injury comprises the following steps:

[0039] (1) Take rhubarb, Magnolia officinalis, Citrus aurantium, Radix Paeoniae Rubra, fried radish seeds, woody incense, fried peach kernels, salvia miltiorrhiza, and Poria cocos in parts by weight, and put them into a grinder, grind them into powder, add Glauber's salt and grind for 45 minutes, and then 400 mesh sieve to obtain refined materials;

...

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Abstract

The invention provides a traditional Chinese medicine composition used for preventing and treating ischemia reperfusion injury, and relates to the field of traditional Chinese medicine compositions. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 13-17 parts of radix et rhizoma rhei, 28-33 parts of natrii sulfas, 27-35 parts of cortex magnoliae officinalis, 12-17 parts of fructus aurantii immaturi, 12-18 parts of radix paeoniae rubra, 25-35 parts of fried semen raphani, 10-20 parts of radix aucklandiae, 10-15 parts of fried semen persicae, 10-13 parts of radix salviae miltiorrhizae, 9-14 parts of poria cocos and 20-30 parts of radix astragali. The traditional Chinese medicine composition achieves the effects of tonifying qi andnourishing kidney, nourishing skeletons, tonifying qi and nourishing yin, promoting metabolism, and achieves the purpose of preventing the ischemia reperfusion injury.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicine compositions, in particular to a traditional Chinese medicine composition for preventing ischemia-reperfusion injury. Background technique [0002] Tissue damage caused by human ischemia is the main cause of fatal diseases, but during the rescue and treatment of ischemic diseases, medical scientists have gradually discovered that the main factor causing tissue damage is not ischemia itself, but After the blood supply is restored, excessive free radicals attack the cells in the tissue that has regained the blood supply. This kind of damage is called "tissue ischemia-reperfusion injury". Increasingly, there is much evidence that ischemia alone is not sufficient to cause tissue damage, but that damage occurs when blood supply is suddenly restored (ie, reperfusion) after a period of ischemia. [0003] The authorized announcement number is CN103800712B, which discloses a traditional Chinese...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61P9/10A61K33/04
CPCA61K33/04A61K36/076A61K36/285A61K36/31A61K36/481A61K36/537A61K36/575A61K36/65A61K36/708A61K36/71A61K36/736A61K36/752A61K2236/331A61P9/10A61K2300/00
Inventor 朱鹏飞王猛刘淑娟张云杰刘昕烨田昭春朱勇
Owner 朱鹏飞
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