Full-automatic dysbacteriosis detection method

A technology of flora imbalance and detection method, which is applied in measurement devices, preparation of test samples, material analysis by optical means, etc. Effect

Pending Publication Date: 2019-01-01
上海景琦医疗技术有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0009] However, after these techniques are used for in situ specimen smear and suspension processing, ideas and equipment specially used for judging flora imbalance through microscopic magnified image analysis have not yet appeared, and there are deficiencies, which cannot meet the needs of social development. needs

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0034] This embodiment is a morphological analysis method that can make more samples more intuitively displayed. Direct images are collected through microscopic magnification and electronic image acquisition technology, and an image database of normal flora and flora imbalance is established, and then AI (automatically ) Intelligent recognition technology analyzes and judges whether the flora is imbalanced, and is also used for the diagnosis of whether the flora imbalance is completely or partially restored to a normal state after treatment.

[0035] Detection process:

[0036] 1) Collect specimens from animal and human body with bacteria (a mature technique commonly used in hospital clinics).

[0037] 2) Dilute the specimen into a suspension or directly make slices, and collect direct images using microscopic magnification and electronic image acquisition technology (the technology has been applied clinically in hospitals, but it is not specifically used for the diagnosis of ...

Embodiment 2

[0046] This embodiment combines microscopic amplification and electronic image acquisition with bacterial staining, biochemical reaction of bacterial products, and immunohistochemical staining to improve the clarity and distinction of microorganism display. Make the image data have more definite identification data, which is better used for the diagnosis of flora imbalance.

[0047] 1) Collect specimens from animal and human body with bacteria.

[0048] 2) Dilute the specimen into a suspension or directly make slices (a mature medical clinical method), and perform bacterial staining and (or) biochemical reaction color development of bacterial products and (or) immunohistochemical staining. Color display of part or all of the cells.

[0049] 3) Apply microscopic magnification and electronic image acquisition technology to collect images after staining (the technology has been applied clinically in hospitals, but it is not specifically used for the diagnosis of bacterial flora). ...

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Abstract

The invention discloses a full-automatic dysbacteriosis detection method which comprises the following steps of collecting a plurality of specimens at parts with bacteria of animals and humans, collecting images by utilizing a microscopic magnification and electronic image collection technology, establishing an image database of a normal flora and dysbacteriosis, and then utilizing an AI (full-automatic) intelligent recognition technology to judge whether dysbacteriosis occurs or not. The full-automatic dysbacteriosis detection method can also be used for diagnosing whether the dysbacteriosisis thoroughly or partly recovered to a normal state after being treated or not, is excellent in practicability, is a very good innovation scheme and has a great market popularization prospect.

Description

technical field [0001] The invention relates to the technical field of biological detection, in particular to a fully automatic detection method for flora imbalance. Background technique [0002] Normally, microorganisms, hosts and the external environment maintain an ecological balance relationship. If there is an ecological imbalance among the three, it is called dysbiosis. The dysbiosis is a problem often encountered in basic and clinical research. It is the initial factor of exogenous infection and endogenous infection. Once it occurs, it is difficult to control . There are many factors that cause flora imbalance, including dietary factors, flora change factors, drug metabolism factors, age factors and gastrointestinal immune dysfunction factors. Therefore, research on the structural diversity and population dynamics of the intestinal flora is of vital significance for the treatment of dysbiosis. [0003] The most common and familiar flora disorder is the symptom of d...

Claims

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Application Information

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IPC IPC(8): G01N1/28G01N21/84
CPCG01N1/28G01N21/84
Inventor张烜洁
Owner上海景琦医疗技术有限公司