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6 results about "Clinical method" patented technology

The clinical method is the means by which physicians discover facts about the sick or well patient and enter them into the diagnostic and therapeutic process in equal partnership with information about disease, pathophysiology, and technology. The inadequacy of the clinical method as currently taught and practiced creates problems...

Clinical two-way detection method, system, device and medium

PendingCN122291040APulse rateNursing care
This application provides a clinical method, system, device, and medium for detecting bowel and bladder movements. First, raw pulse rate time-series data of the patient is collected. The raw pulse rate time-series data undergoes quality verification and signal cleaning to obtain effective pulse rate time-series data. Based on the effective pulse rate time-series data, the mean pulse rate within the current detection window is calculated, and a pre-determined individualized resting pulse rate baseline value is obtained. The difference between the mean pulse rate within the current detection window and the individualized resting pulse rate baseline value is determined as the dynamic pulse rate offset. The dynamic pulse rate offset is judged using predefined bowel and bladder behavior detection rules, and the event confidence level for the current time period is output. The event confidence level is compared with a preset clinical decision threshold. If the event confidence level exceeds the clinical decision threshold, a graded early warning signal is generated and pushed to the clinical nursing system. The above scheme can achieve non-invasive detection of clinical bowel and bladder events.
Owner:ZHEJIANG CHINESE MEDICAL UNIVERSITY

Subcutaneous (SC) administration of anti-C5 antibodies for treatment of complement-associated conditions

Provided are methods for clinical treatment of complement-associated conditions comprising administering to the patient an anti-C5 antibody, or antigen binding fragment thereof, wherein the anti-C5 antibody, or antigen binding fragment thereof, is administered (or is for administration) subcutaneously according to a particular clinical dosage regimen (i.e., at a particular dose amount and according to a specific dosing schedule). In one embodiment, the patient has previously been treated with eculizumab (SOLIRIS®) or ravulizumab (ULTOMIRIS®); particularly intravenously administered SOLIRIS® or ULTOMIRIS®.
Owner:ALEXION PHARMACEUTICALS INC

Method for predicting preeclampsia risk

The invention discloses a method for predicting preeclampsia risk, and relates to the technical field of intelligent medical treatment and predictive medicine. According to the method, a three-order composite mathematical model of static feature weighting, dynamic time attenuation and linear probability mapping is constructed for the first time, the model is complete in structure, the three core problems of feature contribution degree quantification, time effect correction and risk probability nonlinear conversion are scientifically solved, and the limitation of a traditional simple linear model is broken through; according to the method, through multi-dimensional data fusion and machine learning optimization, the model obtains AUCgt on an independent test set; 0.93, the accuracy is gt; the method has excellent performance of 90%, the false positive rate is reduced to 8% or below, the method is far superior to an existing clinical method, and a reliable basis is provided for early accurate intervention; according to the method, the dynamic time attenuation coefficient Ktime is introduced, so that the model has the perception ability in the time dimension, and detection results at different time points during pregnancy can be scientifically corrected and longitudinally compared.
Owner:CHONGQING MEDICAL UNIVERSITY

Real-time CBCT (Cone Beam Computed Tomography) guided median relationship determination method, system and equipment and storage medium

ActiveCN121359993AMedical simulationImpression capsSpatial mappingLower Jaw Tooth
The invention discloses a real-time CBCT (Cone Beam Computed Tomography)-guided median relationship determination method, system and equipment and a storage medium. The method comprises the following steps: acquiring three-dimensional data of dental arches of upper and lower jaws and jaw bones through intraoral scanning and CBCT scanning, and fitting to establish a virtual patient model; acquiring a spatial position relationship between the motion acquisition marker and the dentition of the patient; taking dental arch feature points by using a probe point, and establishing a space mapping relation from the motion acquisition marker to a CBCT coordinate system; the position of a marker is tracked in real time through an electronic plane bow system, and the position of a condylar process in a glenoid fossa is dynamically displayed in real time on a CBCT image based on a space mapping relation; a physician preliminarily determines a median relation position candidate in combination with a clinical technique under real-time visual guidance; guiding the patient to perform joint function movement, synchronously monitoring the joint function and masticatory muscle movement, and determining the final median relation position after the temporomandibular joint function health is verified. According to the invention, chair-side real-time visualization and functional verification are realized, and the diagnosis and treatment efficiency of jaw position determination is obviously improved.
Owner:SICHUAN UNIVERSITY WEST CHINA XIAMEN HOSPITAL (WEST CHINA MEDICAL XIAMEN INSTITUTE SICHUAN UNIVERSITY)

Method for mitigating pulpal pain in symptomatic patients and preventing unnecessary endodontic treatment

ActiveUS12496176B1Organic active ingredientsImpression capsEndodontic therapyPulp (tooth)
The present invention provides a structured, biologically based clinical method for mitigating symptomatic pulpal conditions and preventing unnecessary endodontic treatment. Targeted at teeth with vital pulps and reversible inflammation, the protocol combines selective caries removal, pulp protection using calcium hydroxide or MTA, a sedative zinc oxide-eugenol base, and provisional sealing with moisture-setting cement. The method includes diagnostic, therapeutic, and follow-up steps, with one-week, one-month, and three-month evaluations to assess healing. If symptoms persist, root canal therapy is initiated; if asymptomatic, definitive restoration is performed. Annual monitoring ensures long-term pulpal stability. This reproducible approach prioritizes pain control, infection management, pulp preservation, and tooth longevity. It provides an evidence-based alternative to conventional endodontics, reducing overtreatment while supporting functional and biological integrity of the dental organ.
Owner:ROMERO VASQUEZ MARIA I

Real-time cbct-guided centric relation determination method, system, device, and storage medium

ActiveCN121359993BMedical simulationImpression capsSpatial mappingLower Jaw Tooth
The application discloses a kind of real-time CBCT guided centric relation determination method, system, equipment and storage medium. Upper and lower jaw dental arch and jaw three-dimensional data are obtained by intraoral scanning and CBCT scanning, and a virtual patient model is fitted and established;Obtain the spatial position relationship between motion acquisition marker and patient dentition;Use probe to pick up dental arch feature points, establish the spatial mapping relationship from motion acquisition marker to CBCT coordinate system;Real-time tracking of marker position is realized through electronic facebow system, and the position of condyle in glenoid cavity is dynamically displayed in real time on CBCT image based on spatial mapping relationship;Under the guidance of real-time visualization, the clinician preliminarily determines the centric relation position candidate in combination with clinical method;Guide the patient to carry out joint function movement, and monitor the joint function and masticatory muscle activity synchronously, and determine the final centric relation position after verifying the health of temporomandibular joint function.The application realizes chair-side real-time visualization and function verification, and significantly improves the diagnosis and treatment efficiency of jaw position determination.
Owner:SICHUAN UNIVERSITY WEST CHINA XIAMEN HOSPITAL (WEST CHINA MEDICAL XIAMEN INSTITUTE SICHUAN UNIVERSITY)