A preparing method of a traditional Chinese medicinal composition for treating xerophthalmia

A composition and technology for dry eye syndrome, applied in the direction of drug combinations, pharmaceutical formulas, medical preparations containing active ingredients, etc., can solve problems such as insufficient secretion of mucin layer, unsatisfactory preventive effect, and poor meibomian gland function , to achieve the effect of treating dry eye syndrome, low cost, and low side effects

Inactive Publication Date: 2019-01-15
陆文秀
View PDF0 Cites 0 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

2. Insufficient secretion of oil layer: meibomian gland dysfunction due to eyelid disease
3. Insufficient mucin layer secretion: vitamin A1 deficiency, chronic conjunctivitis, chemical burns, etc.
[0003] At present, although there are drugs for the treatment of dry eye syndrome, most of them are chemical drugs, which have the disadvantages of large side effects and unsatisfactory preventive effects.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] Party:

[0028] 10 parts of chrysanthemum, 5 parts of Qinpi, 10 parts of dodder, 10 parts of Tianma, 15 parts of Zhuru,

[0029] Cassia 5 parts, Horsetail 10 parts, Rhodiola 5 parts, Rehmannia 10 parts, Perilla 5 parts,

[0030] 10 parts of dog liver dish, 10 parts of poria cocos skin, 5 parts of morning glory.

[0031] Preparation:

[0032] (1) Take chrysanthemum, bark of Qin, dodder, Gastrodia elata, Zhuru, cassia and horsetail, add 6 times the volume of 80% ethanol, reflux extraction for 3 times, each time for 2 hours, combine the extracts, and concentrate to obtain liquid extract A ;

[0033] (2) Take rhodiola rosea, rehmannia glutinosa, perilla, dog liver dish, poria cocos skin and morning glory, add 8 times the volume of pure water, heat to boil, reflux extraction 3 times, each time 2 hours, combine the extracts, concentrate to obtain a flow immersion ointment B;

[0034] (3) Combine and mix the above liquid extract A and liquid extract B, and place at room t...

Embodiment 2

[0037] Party:

[0038] 10 parts of chrysanthemum, 25 parts of Qinpi, 20 parts of dodder, 30 parts of Tianma, 25 parts of Zhuru,

[0039] Cassia 35 parts, Horsetail 20 parts, Rhodiola rosea 25 parts, Rehmannia glutinosa 25 parts, Perilla 25 parts,

[0040] 30 parts of dog liver dish, 20 parts of poria cocos skin, 35 parts of morning glory.

[0041] Preparation:

[0042] (1) Take chrysanthemum, bark of Qin, dodder, Gastrodia elata, Zhuru, cassia and horsetail, add 10 times the volume of 80% ethanol, reflux extraction for 3 times, each time for 4 hours, combine the extracts, and concentrate to obtain liquid extract A ;

[0043] (2) Take rhodiola rosea, rehmannia glutinosa, perilla, dog liver dish, poria cocos bark and morning glory, add 12 times the volume of pure water, heat to boil, reflux and extract 3 times, each time for 4 hours, combine the extracts, and concentrate to obtain a liquid immersion ointment B;

[0044] (3) Combine and mix the above-mentioned liquid extract...

Embodiment 3

[0047] Party:

[0048] 10 parts of chrysanthemum, 10 parts of Qinpi, 12 parts of dodder, 15 parts of Gastrodia elata, 18 parts of Zhuru,

[0049] 10 parts of cassia, 12 parts of horsetail, 10 parts of rhodiola, 15 parts of rehmannia, 10 parts of perilla,

[0050] 15 parts of dog liver dish, 12 parts of poria cocos skin, 10 parts of morning glory.

[0051] Preparation:

[0052] (1) Take chrysanthemum, bark of Qin, dodder, Gastrodia elata, Zhuru, cassia and horsetail, add 8 times the volume of 80% ethanol, reflux extraction 3 times, each time for 3 hours, combine the extracts, concentrate to obtain liquid extract A ;

[0053] (2) Take rhodiola rosea, rehmannia glutinosa, perilla, dog liver dish, poria cocos skin and morning glory, add 10 times the volume of pure water, heat to boil, reflux extraction 3 times, each time for 3 hours, combine the extracts, and concentrate to obtain a flow immersion ointment B;

[0054] (3) Combine and mix the above liquid extract A and liquid ...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

PUM

No PUM Login to view more

Abstract

A preparing method of a traditional Chinese medicinal composition for treating xerophthalmia includes (1) adding ethanol having a concentration of 80% into chrysanthemum, ash bark, dodder seeds, tallgastrodia tuber, bamboo shavings, semen cassia, and common scouring rush herb, with the volume of the ethanol being 8-12 times of the volume of the medicines, performing reflux extraction for three times for 2-4 h each time, combining the extract liquids, and concentrating the mixture to obtain extract A; (2) adding pure water into herba rhodiolae, radix rehmanniae, purple common perilla, herb ofchinese dicliptera, Indian bread exodermis and pharbitis seed, with the volume of the pure water being 10-14 times of the volume of the medicines, performing reflux extraction for three times for 2-4h each time, combining the extract liquids, and concentrating the mixture to obtain extract B; (3) mixing the extract A and the extract B, and standing at room temperature for 24-48 h; 4) filtering the mixture, adding conventional adjuvant, and making into liquid preparation or solid preparation. As compared with that prior art, the method of the invention has the advantages of simple process, lowcost, effective integration of various raw materials, simple formula, strict compatibility, accurate dosage, effective treatment of xerophthalmia, good effect and low side effect, and strong adaptability of patients.

Description

technical field [0001] The invention relates to a preparation method of a traditional Chinese medicine composition for treating dry eye, and belongs to the technical field of traditional Chinese medicine preparations. Background technique [0002] Dry eye syndrome refers to the general term for various diseases caused by abnormal tear quality or quantity or abnormal dynamics caused by any reason, resulting in decreased tear film stability, accompanied by ocular discomfort and (or) ocular surface tissue lesions. Also known as keratoconjunctival sicca. Common symptoms include dry eyes, easy fatigue, itchy eyes, foreign body sensation, burning sensation, sticky secretions, fear of wind, photophobia, and sensitivity to external stimuli; sometimes the eyes are too dry, and there is basically insufficient tear fluid, which stimulates the reflex In severe cases, the eyes will be red and swollen, congested, keratinized, and the corneal epithelium is broken and there are filaments a...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to view more

Application Information

Patent Timeline
no application Login to view more
Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/899A61P27/02
CPCA61K36/287A61K36/076A61K36/11A61K36/19A61K36/21A61K36/39A61K36/41A61K36/43A61K36/482A61K36/535A61K36/63A61K36/804A61K36/8988A61K36/899A61K2236/331A61K2236/333A61K2236/39A61K2300/00
Inventor 陆文秀
Owner 陆文秀
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Try Eureka
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap