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Medicament genomics analysis system

A genomics and analysis system technology, applied in sequence analysis, bioinformatics, informatics, etc., can solve problems such as inconsistent analysis results, incomplete analysis, and report errors, so as to shorten the training cycle, reduce error rates, and reduce The effect of labor costs

Pending Publication Date: 2019-06-18
郑州金域临床检验中心有限公司
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AI Technical Summary

Problems solved by technology

The above-mentioned manual analysis requires individual operations in sequence, the steps are cumbersome, time-consuming, and consume a lot of manpower and time. It is easy to cause incomplete analysis or inconsistent analysis results, and manual input can easily lead to errors in the report

Method used

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Embodiment Construction

[0028] The following describes the technical solutions in the embodiments of the present invention clearly and completely. Obviously, the described embodiments are only a part of the embodiments of the present invention, rather than all the embodiments. Based on the embodiments of the present invention, all other embodiments obtained by those of ordinary skill in the art without creative work shall fall within the protection scope of the present invention.

[0029] The invention provides a pharmacogenomics analysis system, including a data conversion module, a data analysis module and a data integration module;

[0030] The data conversion module is used to receive the results of MassARRAY disassembly, obtain the gene sequence from the disassembly result, and obtain the experiment number, Rs number and genotyping result corresponding to the gene sequence;

[0031] The data analysis module is used to receive the experiment number, Rs number, genotyping result and gene sequence, and qu...

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Abstract

The invention provides a medicament genomics analysis system which comprises a data conversion module, a data analysis module and a data integrating module. The data conversion module is used for receiving a MassARRAY detecting result, acquires a gene sequence from the detecting result, and acquires an experiment number, an Rs number and a genotyping result which correspond with the gene sequence.The data analysis module is used for receiving the experiment number, the Rs number, the genotyping result and the gene sequence and acquires medicament information which is related with the gene according to a medicament-gene rule. The data integrating module is used for receiving and integrating clinical information and the medicament information which is related with the gene. The medicament genomics analysis system according to the invention replaces personnel in arranging the MassARRAY detecting result, and performs database, guidance and literature comparison on the genotyping result. The analysis rate in the same condition is hundreds times of that of analysis reporting personnel, thereby shortening an analysis reporting period.

Description

Technical field [0001] The invention belongs to the technical field of intelligent medical diagnosis systems, and particularly relates to a pharmacogenomics analysis system. Background technique [0002] Pharmacogenomics has become an important tool for guiding individualized clinical medication, assessing the risk of serious adverse drug reactions, guiding the development of new drugs, and evaluating new drugs. It studies the dynamics of drugs and their metabolites in the body over time, and how these dynamic behaviors affect drug efficacy , How to be affected by the way of drug input (dose form, dosage, route of administration, etc.) and body conditions (race, gender, age, disease status), has important practical value for the development of new drugs, especially the clinical rational use of drugs. Important enzymes related to metabolism include microsomal mixed functional oxidases (flavin protein, heme protein and phosphatidylcholine) and non-microsomal enzymes (specific metab...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): G16B50/00G16B30/00
Inventor 张暋马新利佘维谷晓辉
Owner 郑州金域临床检验中心有限公司
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