Bacillus subtilis having effects of relieving enteritis and promoting development of intestines and application

A technology of Bacillus subtilis and intestinal development, which is applied in the field of microorganisms, can solve the problems such as patent publications that have not yet been found, and achieve the effect of repairing and enhancing the mucosal barrier function, wide application prospects, and promoting intestinal development

Active Publication Date: 2019-08-20
TIANJIN UNIV OF SCI & TECH
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  • Abstract
  • Description
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  • Application Information

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Problems solved by technology

[0006] Through the search, no patent publications related to the patent application of the present invention have been found

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  • Bacillus subtilis having effects of relieving enteritis and promoting development of intestines and application
  • Bacillus subtilis having effects of relieving enteritis and promoting development of intestines and application
  • Bacillus subtilis having effects of relieving enteritis and promoting development of intestines and application

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Embodiment Construction

[0031] The present invention will be described in further detail below in conjunction with specific examples. The following examples are only descriptive, not limiting, and cannot limit the protection scope of the present invention.

[0032] The raw materials used in the present invention, unless otherwise specified, are conventional commercially available products; the methods used in the present invention, unless otherwise specified, are conventional methods in the art.

[0033] A strain of Bacillus subtilis that relieves enteritis and promotes intestinal development, named RZ001, taxonomic name Bacillus subtilis., preservation number: CGMCC NO: 17116, preservation date: January 7, 2019, Chaoyang District, Beijing No. 3, No. 1 Yard, Beichen West Road. Preservation unit: General Microbiology Center of China Committee for the Collection of Microbial Cultures.

[0034] Preferably, the Bacillus subtilis is obtained from the feces of healthy newborns;

[0035] Alternatively, the...

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Abstract

The invention relates to bacillus subtilis having effects of relieving enteritis and promoting development of intestines. The bacillus subtilis is named as RZ001, the category name is Bacillus subtilis., the preservation No. is CGMCC NO:17116, the preservation date is 7, January, 2019, the preservation address is No.3, No. 1 Courtyard, Beichen West Road, Chaoyang District, Beijing, and the preservation unit is China General Microbiological Culture Collection Center(CGMCC). The bacterial strain has the functions of repairing and strengthening mucosal barrier, has the function of treating inflammatory and allergic dermatosis enteritis, and can also promote the development of the intestines. The bacterial strain is hopeful to be used for preparing drugs and fermented foods for preventing andtreating intestine inflammation and promoting development, and has broad application prospect.

Description

technical field [0001] The invention belongs to the technical field of microbes, in particular to a bacillus subtilis strain capable of alleviating enteritis and promoting intestinal development and its application. Background technique [0002] Inflammatory bowel disease (IBD) is a chronic non-specific intestinal inflammatory disease of unknown cause, including ulcerative colitis (UC), Crohn's disease (CD), Its incidence rate is increasing year by year, but the pathogenesis is still unclear, and it has the characteristics of high recurrence rate, which seriously affects the quality of life of patients. Intestinal microecological disorder leading to immune imbalance may be an important link in the pathogenesis of IBD. The intestinal flora of susceptible people breaks through the intestinal epithelial barrier, the immune system is activated by various microbial antigens, and the activation of inflammatory cytokines leads to an inflammatory response in the colonic mucosal tiss...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C12N1/20A61K35/742A61P1/00A61P29/00A23L29/00A23C9/12A23L11/00C12R1/125A23L11/50
CPCC12N1/20A61K35/742A61P1/00A61P29/00A23L29/065A23C9/1203A23L11/50C12R2001/125C12N1/205
Inventor 王楠张同存李艳茹张腾勋郭聪聪罗学刚李中媛宋亚囝齐威
Owner TIANJIN UNIV OF SCI & TECH
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