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Low complexity flow control in a microfluidic mixer

A technology of microfluidics, fluid flow, applied in the field of hydraulic devices, which can solve problems such as scale hindering the application of known solutions

Pending Publication Date: 2019-09-06
PRECISION NANOSYSTEMS ULC
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The scale of manufacturing hinders the application of known solutions

Method used

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  • Low complexity flow control in a microfluidic mixer
  • Low complexity flow control in a microfluidic mixer
  • Low complexity flow control in a microfluidic mixer

Examples

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Embodiment Construction

[0037] The following terms, components and any reference numerals are now described, followed by details of the components which are now grouped together with reference to the figures, followed by a description of how to use the embodiments of the invention.

[0038] The term "block" 70 is used herein to describe the solid form that forms the microchannels, inlets, mixing zone(s), outlets, and passive capillary valves.

[0039] "Downstream" and "upstream" in this application are intended to mean the direction of flow of fluid in a microchannel from an inlet or input location towards an outlet or outlet point.

[0040] Injection molding is a standard manufacturing method for many plastics. A metal block, preferably composed of chrome steel, is machined into the desired shape. Use a round cutting blade. In micromachining applications, the tool size must be very small, but as size decreases, durability decreases. A 0.3mm cutter is the preferred minimum for strength, which limi...

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Abstract

The present invention provides a microfluidic mixing platform having a bulk, the platform including an inlet well, a microchannel, a passive capillary valve a mixing feature and an outlet. The passivecapillary valve prevents unwanted capillary flow along the microchannel. The passive capillary valve comprises a widening of the microchannel relative to the direction of fluid flow, and the angle has a graduated profile. The mixing platform bulk comprises a rigid matrix capable of machine manufacture. A method of preventing backflow in a microfluidic mixer is also provided.

Description

[0001] Cross References to Related Applications [0002] Priority is claimed to U.S. Provisional Application 62 / 447,653, filed January 18, 2017. Background technique [0003] (a) field [0004] The disclosed subject matter generally relates to hydraulics within microfluidic mixing platforms for mixing materials for biological or medical research. [0005] Polydimethylsiloxane (PDMS) has been used for many years in the fabrication of microfluidic mixing platforms. PDMS has unique flow characteristics that are easy to handle, and PDMS is considered "safe" for biological substances. However, PDMS is not a preferred material in standard injection molding processes suitable for mass production. [0006] "Capillarity" is the movement of a fluid through a channel due to forces caused by surface interactions between the fluid and the channel walls, and is important when the volume is very small and the channel is very narrow. If the diameter of the channel is small enough, the co...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): B01F15/02B01F5/00B81B1/00B81B7/00
CPCB01F33/3035B01F25/821B01F35/71
Inventor 安德烈·维尔德张韶方蒂莫西·利弗
Owner PRECISION NANOSYSTEMS ULC