Sarcococca ruscifolia stapf granule, and preparation method and application of sarcococca ruscifolia stapf granule
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A wild fan flower and the technology of describing wild fan flower are applied in the direction of medical formula, chemical analysis by titration method, medical preparations containing active ingredients, etc., to achieve the effects of short production cycle, reasonable design, and simple and easy method
Pending Publication Date: 2019-10-08
GUANGXI INST OF CHINESE MEDICINE & PHARMA SCI
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But there is no preparation of wild fan flower on the market at present, and there is no related report that wild fan flower is made into a related preparation for anti-ulcer or for analgesia
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Embodiment 1
[0030] according to figure 1 The process flow chart of preparing wild fan flower granules, the specific operation steps are as follows:
[0031] Take 500g of the dried whole plant of the wild fan flower, extract twice with 3L of 50% ethanol under reflux, each time for 1.5 hours, combine the filtrate, concentrate the filtrate at 60°C, recover ethanol, and concentrate to obtain a thick paste with a relative density of 1.32. Add 940g sucrose, mix well, make granules, dry, make 1000g, measure its total alkaloid content. After calculation, the total alkaloid content per gram of granule is 2.3mg.
Embodiment 2
[0033] Take 500g of the dried whole plant of the wild fan flower, extract twice with 5L of 50% ethanol under reflux, each time for 2 hours, combine the filtrate, concentrate the filtrate at 60°C, recover ethanol, and concentrate to obtain a thick paste with a relative density of 1.34. Add 920g of sucrose, mix well, make granules, dry, make 1000g, measure its total alkaloid content. After calculation, the total alkaloid content per gram of granule is 2.7mg.
Embodiment 3
[0035] Take 500 g of the dried whole plant of the wild fan flower, extract twice with 7L of 50% ethanol under reflux, each time for 3 hours, combine the filtrate, concentrate the filtrate at 60°C, recover ethanol, and concentrate to obtain a thick paste with a relative density of 1.35. Add 910g of sucrose, mix well, make granules, dry, make 1000g, measure and measure its total alkaloid content. After calculation, the total alkaloid content per gram of granule is 2.9mg.
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Abstract
The invention discloses a sarcococca ruscifolia stapf granule, and a preparation method and application of the sarcococca ruscifolia stapf granule, and belongs to the technical field of granule preparation. The preparation method of the sarcococca ruscifolia stapf granule includes the following steps that the whole plant of sarcococca ruscifolia stapf is dried, and crushing, water-alcohol extraction, concentration, mixing with sucrose, granulating and drying are conducted; and the prepared sarcococca ruscifolia stapf granule has obvious anti-ulcer and analgesic pharmacological effects. The sarcococca ruscifolia stapf granule is researched and developed, the further development and utilization of products related to sarcococca ruscifolia stapf medicinal materials are facilitated, the research and development of the sarcococca ruscifolia stapf granule are of great significance for the development of characteristic medicinal materials of Guangxi and the development of products with high technology and high added value, market competitiveness can be improved, and potential and inestimable social and economic benefits are generated.
Description
technical field [0001] The invention relates to the technical field of preparation of granules, in particular to a wild fan flower granule and its preparation method and application. Background technique [0002] In recent years, the incidence of stomach disease has not only remained high, but even has a rising trend. Stomach disease is almost the most common disease among sub-healthy people. Common stomach diseases include acute gastritis, chronic gastritis, peptic ulcer, functional dyspepsia, etc. Stomach trouble and stomach discomfort are the most common diseases, and one of the major characteristics of this disease is that it is difficult to cure and easily recurs. Of course, the consumption of gastric medicines is equivalent to the rate of increase in the prevalence of stomach diseases. Due to various reasons, the market for gastric medicines is growing at an annual growth rate of 22%, and the market demand is strong. [0003] Experimental and clinical studies in rece...
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