Chromosome sequencing method based on stripe recognition

Abstract

The invention discloses a chromosome sorting method based on stripe recognition, and belongs to the technical field of chromosome image processing. According to an existing chromosome sequencing method, due to the fact that manual recognition is prone to interference, selection and arrangement accuracy is low, and structural comparison of doctors is affected. The method comprises the following steps: step 1, obtaining a chromosome karyotype diagram; step 2, carrying out chromosome cutting on the karyotype diagram to obtain a plurality of chromosome images, and identifying chromosome types; 3,extracting a plurality of images of chromosomes of the same number, and identifying chromosome stripe types based on an intelligent algorithm model; and step 4, sorting the plurality of divided chromosome images according to the chromosome stripe type changes of the chromosome images. The strip types of the chromosome images can be predicted, the chromosome strip number can be accurately recognized, reasonable sorting is performed according to the chromosome strip number, a doctor can conveniently observe the chromosome structure, the burden of the doctor can be effectively reduced, and time and labor are saved.

Description

technical field [0001] The invention relates to a chromosome sorting method based on band identification, belonging to the technical field of chromosome image processing. Background technique [0002] Modern cytogenetics has shown that in various tissues of the human body, although the various components of the cells are different and the structures vary greatly, the chromatin in the nucleus remains relatively constant. In somatic cell division, the 46 chromosomes are regularly replicated and distributed equally to the two daughter cells, so both daughter cells retain the same 46 chromosomes. [0003] In the process of cell culture, common chromosome banding models have 300, 400, 550, 700, and 800 bands, and the more bands, the more detailed the structural characteristics of the chromosome. [0004] In the existing chromosome sorting method, the doctor needs to select a number of well-dispersed, moderately long, and clear metaphase pictures, count these pictures one by one,...

AI Technical Summary

Problems solved by technology

[0006] First, manual selection and manual arrangement of chromosome karyotype maps are required, and the detection method is inefficient and time-consuming;

[0007] Second, due to the strong subjectivity of artificial recognition, it is easy to be disturbed, resulting in low accuracy of selection and arrangement, which affects the comparison and observation of the structure by doctors

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