Beautification and skin restoration sodium hyaluronate gel encapsulating stem cell complex factors

A sodium hyaluronate and compound factor technology, applied in the field of medical beauty and skin repair, can solve the problems of heterologous ingredients, increase the probability and risk of allergies, restore skin youthfulness, reduce the probability and risk of allergies, reduce Effects of Allergy Risk

Inactive Publication Date: 2019-12-31
西安东澳生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] To sum up, the existing problems in the prior art are: fetal calf serum is introduced into the preparation of the stem cell secreted factor used in the prior art for the preparation of the stem cell secreted factor for beauty and skin care, which contains heterologous components, which increases the probability and risk of allergies

Method used

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  • Beautification and skin restoration sodium hyaluronate gel encapsulating stem cell complex factors
  • Beautification and skin restoration sodium hyaluronate gel encapsulating stem cell complex factors
  • Beautification and skin restoration sodium hyaluronate gel encapsulating stem cell complex factors

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preparation example Construction

[0075] Such as figure 1 As shown, the preparation method of the cosmetic and skin repair sodium hyaluronate gel containing stem cell complex factors provided by the embodiments of the present invention comprises the following steps:

[0076] S101: Obtain umbilical cord mesenchymal stem cells with the lowest human immunogenicity and the strongest cell differentiation potential through tissue block culture method, purify, expand culture, and collect during the period of vigorous cell division (about 70% to 80% of the area of ​​the culture bottle) Cell culture supernatant, after concentration, filtration, protein content determination, quality inspection, to obtain stem cell compound factor solution;

[0077] S102: Then mix the stem cell complex factor solution and sodium hyaluronate evenly to prepare a sodium hyaluronate gel encapsulating the stem cell complex factor.

[0078] The primary isolation and culture method of human umbilical cord mesenchymal stem cells provided in th...

Embodiment 1

[0128] Embodiment 1: Trial example of stem cell complex factor gel

[0129] 20 people with different facial problems were selected from the market, and the stem cell compound factor gel was applied to the subjects' faces, and a needle roller was used to help them track the subjects' facial conditions for 3 months.

[0130] The faces of the people who try the product of the present invention are all improved. The improvement effect is manifested in the following aspects: the reduction of fine facial wrinkles, the reduction of red blood streaks, the reduction of sebum secretion, the reduction of pigmentation spots, and the fair and clear skin.

Embodiment 2

[0132] Ms. Li, 60 years old, usually takes simple basic facial care. As she ages, facial wrinkles deepen and her skin becomes dry, sagging, and dull. After trying the stem cell complex factor gel, the skin is translucent, the spots are lightened, the skin is rosy and plump, and the wrinkles are reduced.

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Abstract

The invention belongs to the technical field of medical cosmetology and skin restoration, and discloses beautification and skin restoration sodium hyaluronate gel encapsulating stem cell complex factors. The beautification and skin restoration sodium hyaluronate gel encapsulating the stem cell complex factors is prepared from the stem cell complex factors and sodium hyaluronate. Umbilical cord mesenchymal stem cells with the lowest human immunogenicity and strongest cell differentiation potential are obtained by a tissue block culture method; purification and enlargement culture are performed;cell culture liquid supernatant is collected in a cell division exuberant period (the cells approximatively grow to 70 to 80 percent of the area of a culture bottle), and a stem cell complex factor solution is obtained through concentration, filtration, protein content determination and quality inspection; and then, the stem cell complex factor solution and the sodium hyaluronate are uniformly mixed to be prepared into the sodium hyaluronate gel encapsulating the stem cell complex factors. The sodium hyaluronate gel encapsulating the stem cell complex factors can be used in the fields of beautification and skin restoration, and achieves the effects of improving the skin color and restoring the young state of the skin.

Description

technical field [0001] The invention belongs to the technical field of medical cosmetology and skin repair, in particular to a sodium hyaluronate gel for cosmetology and skin repair containing stem cell compound factors Background technique [0002] At present, the closest existing technology: Stem cells are a kind of cells with multidirectional differentiation potential and infinite self-renewal and replication ability. Under certain conditions, they can differentiate into specific tissues. During the process of growth, proliferation, and differentiation, stem cells will secrete complex factor active substances such as growth factors, cytokines, regulatory peptides, and collagen that promote cell growth and regulate the surrounding environment. The complex factors also contain a variety of cell-specific proteins, lipids and nucleic acid substances, which can release signal molecules and transmit them to other cells, thereby stimulating skin tissue to repair and adjust. [...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/06A61K47/36A61K35/28A61K31/728A61P17/02A61P17/00
CPCA61K9/0014A61K9/06A61K47/36A61K35/28A61K31/728A61P17/02A61P17/00A61K2300/00
Inventor 郭静晁晓东王泊
Owner 西安东澳生物科技有限公司
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