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Pressure drug delivery device and drug storage core layer

A drug delivery device and pressure technology, which is applied in the field of drug delivery, can solve the problems of low bioavailability of drugs, general drug distribution uniformity, and low therapeutic index of drugs, and achieve uniform drug distribution, wide range of dosage forms, Effects with low size requirements

Active Publication Date: 2020-02-28
张子辰
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Traditional external application and transdermal drug delivery methods are common external application, microneedle external application and microneedle injection. Although common external application is low in cost and easy to operate, its absorption efficiency is not high, the bioavailability of the drug is not high, and the therapeutic index of the drug is not high; Although microneedle external application and microneedle injection have improved absorption efficiency, drug bioavailability, and therapeutic index of drugs, they are costly, complicated to operate, generally uniform in drug distribution, and cause damage to the stratum corneum

Method used

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  • Pressure drug delivery device and drug storage core layer
  • Pressure drug delivery device and drug storage core layer
  • Pressure drug delivery device and drug storage core layer

Examples

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Embodiment Construction

[0018] attached by figure 1 It can be seen that the embodiment 1 of the pressure administration device is: it has a negative pressure housing 1, one side of the negative pressure housing 1 is a closed shell, and is provided with a negative pressure exhaust port 3, and the other side is an open end. One side of the open end of the negative pressure housing 1 is equipped with a middle dosing plate 4 with a plurality of concave dosing surfaces on the section line, and the middle dosing board 4 is connected with the connector 6 and the negative pressure housing 1 through a flexible connection. On one side of the drug administration surface of the middle drug administration plate 4, a plurality of convex drug storage core layers 7 are installed in cross-section. Material.

[0019] During work, the drug storage core layer 7 is fixed on the drug delivery surface, and then the middle drug delivery plate 4 is fixed on the connector 6 of the negative pressure shell 1, and the open end ...

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Abstract

The invention relates to a pressure drug delivery device and a drug storage core layer, and is suitable for external and transdermal drug delivery. The pressure drug delivery device comprises a negative-pressure shell. One side of the negative-pressure shell is of an enclosed shell with a negative-pressure air outlet, and the other side of the negative-pressure shell is of an open end. At least one open drug delivery end with one or more recessed drug delivery surfaces on the cross section line, or at least one middle drug delivery plate with one or more recessed drug delivery surfaces on thecross section line, is mounted on the side of the open end of the negative-pressure shell. The drug storage core layer with one or more matched protrusions on the cross section is mounted on the sideof the drug delivery surface. The pressure drug delivery device has the advantages that the surface area of stratum corneum is increased, the thickness is reduced, skin injuries are small, the drug delivery pressure is uniform and high, the drug delivery amount, depth and area are large, the drug delivery distribution is uniform, there is a step-by-step drug delivery process based on infiltration,requirements on the size of delivered particles are low, the dosage form range is wide, the cost is low, and operations are simplified.

Description

technical field [0001] The invention relates to a pressure drug delivery device and a drug storage core layer, which are suitable for external application and percutaneous drug delivery. Background technique [0002] Traditional external application and transdermal drug delivery methods are common external application, microneedle external application and microneedle injection. Although common external application is low in cost and easy to operate, its absorption efficiency is not high, the bioavailability of the drug is not high, and the therapeutic index of the drug is not high; Although microneedle external application and microneedle injection have improved absorption efficiency, drug bioavailability, and drug therapeutic index, they are costly, complicated to operate, generally uniform in drug distribution, and cause damage to the stratum corneum. Contents of the invention [0003] The object of the present invention is to provide a method that can increase the surfa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61M37/00
CPCA61M37/00
Inventor 张子辰
Owner 张子辰
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