Eight-treasure marrow-supplementing and blood-generating capsule traditional Chinese medicine composition and preparation method thereof

A composition and marrow-replenishing technology, applied in drug combination, capsule delivery, pharmaceutical formula, etc., can solve problems such as side effects and unsatisfactory curative effect of aplastic anemia

Inactive Publication Date: 2020-06-26
陕西郝其军制药股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

The inventor has done a lot of research on the prior art, and found that the 5 types disclosed in the above p...

Method used

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  • Eight-treasure marrow-supplementing and blood-generating capsule traditional Chinese medicine composition and preparation method thereof
  • Eight-treasure marrow-supplementing and blood-generating capsule traditional Chinese medicine composition and preparation method thereof
  • Eight-treasure marrow-supplementing and blood-generating capsule traditional Chinese medicine composition and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0081] The present invention is made from the raw material medicine of following weight ratio:

[0082]

[0083] Its preparation method is as follows:

[0084] (1) Preparation of Zihe powder: Take the fresh human placenta tissue that has been tested by immunology, boil it in 4% pepper water until it floats on the water surface, remove it, remove surface impurities, put it in the oven, dry it below 70°C for 12 hours, take it out , let cool, pass through an 80-mesh sieve, and obtain;

[0085] (2) Preparation of bovine bone marrow powder: take fresh bovine bone marrow, add water to decoct three times, add 6 times the amount of water for the first time, decoct for 2 hours, add 4 times the amount of water for the second and third times, decoct for 1.5 hours respectively, and combine Decoction, filtration, and when the filtrate is concentrated to 80°C, the clear paste with a relative density of 1.10-1.12 is measured, dried below 80°C, pulverized, and passed through a 80-mesh sie...

Embodiment 2

[0088] The present invention is made from the raw material medicine of following weight ratio:

[0089]

[0090] Its preparation method is as follows:

[0091] (1) Preparation of Zihe powder: Take the fresh human placenta tissue that has been tested by immunology, boil it in 4% pepper water until it floats on the water surface, remove it, remove surface impurities, put it in the oven, dry it below 70°C for 12 hours, take it out , let cool, pass through an 80-mesh sieve, and obtain;

[0092] (2) Preparation of bovine bone marrow powder: take fresh bovine bone marrow, add water to decoct three times, add 6 times the amount of water for the first time, decoct for 2 hours, add 4 times the amount of water for the second and third times, decoct for 1.5 hours respectively, and combine Decoction, filtration, and when the filtrate is concentrated to 80°C, the clear paste with a relative density of 1.10-1.12 is measured, dried below 80°C, pulverized, and passed through a 80-mesh sie...

Embodiment 3

[0095] The present invention is made from the raw material medicine of following weight ratio:

[0096]

[0097] Its preparation method is as follows:

[0098] (1) Preparation of Zihe powder: Take the fresh human placenta tissue that has been tested by immunology, boil it in 4% pepper water until it floats on the water surface, remove it, remove surface impurities, put it in the oven, dry it below 70°C for 12 hours, take it out , let cool, pass through an 80-mesh sieve, and obtain;

[0099] (2) Preparation of bovine bone marrow powder: take fresh bovine bone marrow, add water to decoct three times, add 6 times the amount of water for the first time, decoct for 2 hours, add 4 times the amount of water for the second and third times, decoct for 1.5 hours respectively, and combine Decoction, filtration, and when the filtrate is concentrated to 80°C, the clear paste with a relative density of 1.10-1.12 is measured, dried below 80°C, pulverized, and passed through a 80-mesh sie...

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Abstract

The invention discloses an eight-treasure marrow-supplementing and blood-generating capsule traditional Chinese medicine composition and a preparation method thereof. The traditional Chinese medicinecomposition is prepared by processing ten raw material medicines including ginseng, prepared rehmannia root processed with wine, fried bighead atractylodes rhizome, poria cocos, angelica sinensis processed with wine, radix paeoniae alba, ligusticum wallichii, human placenta powder, bovine bone marrow powder and honey-fried licorice root according to a certain proportion into active ingredients ofthe medicines, granulating, drying, and encapsulating, thereby obtaining an eight-treasure marrow-supplementing and blood-generating capsule, wherein the human placenta powder is prepared by selectingfresh human placenta tissues subjected to immunodetection, decocting with 4% pepper water, removing impurities, drying at the temperature of 70 DEG C or below, and screening by virtue of a 80-mesh sieve, and the obtained human placenta powder retains the active ingredients of the human placenta to the greatest degree; and the bovine bone marrow powder is prepared by selecting fresh bovine bone marrow, adding water, decocting, concentrating into clear paste, drying at the temperature of 80 DEG C or below, grinding, and screening by virtue of a 80-mesh sieve, and the obtained bovine bone marrowpowder retains the active ingredients of the bovine bone marrow to the greatest degree. The composition has the effects of tonifying Qi, supplementing marrow and generating blood, is used for treating Qi-blood deficiency type aplastic anemia, leucopenia and the like, and has the symptoms of pale complexion, palpitation and shortness of breath, tiredness and weakness, dizziness, anorexia and loosestool. Compared with the prior art, the composition has the advantages of obvious curative effect on qi-blood deficiency type aplastic anemia, high bioavailability and no toxic or side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition of Bazhen Busui Shengxue capsule and a preparation method thereof, belonging to the technical field of pharmacy. Background technique [0002] Aplastic anemia is mainly a syndrome in which the number of hematopoietic stem cells is reduced or the function is abnormal due to various reasons, thereby causing PB red blood cells, white blood cells and thrombocytopenia. It is difficult to treat clinically and seriously affects people's health. Traditional Chinese medicine has a lot of Chinese medicine compositions in the treatment of aplastic anemia. Because there are many causes of aplastic anemia, it is difficult in the treatment process, and most of the curative effects are not very satisfactory at present. There are fewer Chinese patent medicines in the treatment of Qi and blood deficiency aplastic anemia and leukopenia, which cannot meet the existing clinical needs. [0003] Prior Art ...

Claims

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Application Information

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IPC IPC(8): A61K36/804A61K9/48A61P7/06A61P7/00A61P1/14A61P37/04A61P39/00A61K35/50A61K35/28
CPCA61K9/48A61K35/28A61K35/50A61K36/076A61K36/232A61K36/236A61K36/258A61K36/284A61K36/484A61K36/65A61K36/71A61K36/804A61K2236/331A61K2236/39A61K2236/51A61P1/14A61P7/00A61P7/06A61P37/04A61P39/00A61K2300/00
Inventor 郝彬董昌虎
Owner 陕西郝其军制药股份有限公司
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