Traditional Chinese medicine polysaccharide and preparation method and application thereof

A polysaccharide and traditional Chinese medicine technology, which is applied in pharmaceutical formulations, antibacterial drugs, anti-infective drugs, etc., can solve the problems of virus mutation, pathogen mixed infection, immune suppression and immune failure, and achieves safe use, wide application and wide drug sources. Effect

Pending Publication Date: 2020-08-18
HAINAN JINZHU AGRI DEV CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the veterinary industry generally uses vaccine preparations and chemically synthesized drugs to prevent and treat swine fever, resulting in serious chemical drug residues in livestock and poultry products, and is prone to drug resistance, which seriously affects the quality of livestock and poultry products and poses a threat to the health of consumers. a huge threat
The use of vaccines has played a key role in the prevention and control of epidemic diseases, but some epidemic diseases cause immunosuppression and immune failure due to virus mutation and mixed infection of pathogens

Method used

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  • Traditional Chinese medicine polysaccharide and preparation method and application thereof
  • Traditional Chinese medicine polysaccharide and preparation method and application thereof

Examples

Experimental program
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Effect test

Embodiment 1

[0029] The preparation method of Chinese medicine polysaccharide of the present invention comprises the following steps:

[0030] (1) Grind Yizhi kernels, add 12 times the amount of water to soak for 1 hour, ultrasonically extract for 30 minutes, heat to 90°C, extract for 1.5 hours, filter, add 6 times the amount of water to the filter residue, extract for 1 hour, filter, combine the second filtrate, and reduce Concentrate under pressure to 1.10; put the concentrate at room temperature, add ethanol to make the alcohol content 35%, stir while adding, let stand at 4°C for 12 hours, centrifuge to remove the precipitate, filter the supernatant through membrane to obtain the fine extract, and depressurize After concentration, drying, polysaccharides containing no less than 35% polysaccharides;

[0031] (2) Break the fresh betel nut and perform physical pressing, collect the juice through filtration and separation, and combine the residue at the same time, add 6 times the amount of ...

Embodiment 2

[0034] The preparation method of Chinese medicine polysaccharide of the present invention comprises the following steps:

[0035] (1) Grind Yizhi kernels, add 12 times the amount of water to soak for 1 hour, ultrasonically extract for 30 minutes, heat to 90°C, extract for 1.5 hours, filter, add 6 times the amount of water to the filter residue, extract for 1 hour, filter, combine the second filtrate, and reduce Concentrate under pressure to 1.20; put the concentrate at room temperature, add ethanol to make the alcohol content 35%, stir while adding, let stand at 4°C for 12 hours, centrifuge to remove the precipitate, filter the supernatant through membrane to obtain the fine extract, and depressurize After concentration, drying, polysaccharides containing no less than 35% polysaccharides;

[0036] (2) Break the fresh betel nut and perform physical pressing, collect the juice through filtration and separation, and combine the residue at the same time, add 6 times the amount of ...

Embodiment 3

[0039] The preparation method of Chinese medicine polysaccharide of the present invention comprises the following steps:

[0040] (1) Grind Yizhi kernels, add 12 times the amount of water to soak for 1 hour, ultrasonically extract for 30 minutes, heat to 90°C, extract for 1.5 hours, filter, add 6 times the amount of water to the filter residue, extract for 1 hour, filter, combine the second filtrate, and reduce Concentrate under pressure to 1.10; put the concentrate at room temperature, add ethanol to make the alcohol content 35%, stir while adding, let stand at 4°C for 12 hours, centrifuge to remove the precipitate, filter the supernatant through membrane to obtain the fine extract, and depressurize After concentration, drying, polysaccharides containing no less than 35% polysaccharides;

[0041] (2) Break the fresh betel nut and perform physical pressing, collect the juice through filtration and separation, and combine the residue at the same time, add 6 times the amount of ...

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Abstract

The invention discloses traditional Chinese medicine polysaccharide. The traditional Chinese medicine polysaccharide is prepared from the following raw materials in parts by weight: 20 to 70 parts offructus alpiniae oxyphyllae polysaccharide, 20 to 70 parts of betel nut polysaccharide and 0 to 30 parts of auxiliary materials, the traditional Chinese medicine polysaccharide can be applied to prevention and treatment on infectious diseases of live pigs, a reasonable traditional Chinese medicine formula is selected, the main component is natural south medicine polysaccharide, virus attachment cells can be directly inhibited from entering a cell and virus replication process, the plant polysaccharide serving as an interferon inducer can enhance the functions of macrophages and T cells, so that the number of E-ring forming cells is increased, cytokines are induced, production of interleukin 2 (IL-2) is promoted, endogenous interferon is produced in an animal body, and the antiviral purposeis achieved.

Description

technical field [0001] The invention belongs to the technical field of feed additives, relates to a traditional Chinese medicine polysaccharide, in particular to a traditional Chinese medicine polysaccharide used for preventing and treating pig infectious diseases and a preparation method thereof. Background technique [0002] China's pork production exceeds half of the world, and its pork consumption accounts for nearly 50% of the world's total. China is recognized as a major pork farming country in the world. With the continuous improvement of the pig breeding industry, the scale is also continuously intensified and expanded, bringing many economic benefits to domestic pig farmers, and the premise of ensuring economic benefits is to maintain domestic pigs in a good state to grow. One of the main problems faced by my country's pig production is the inability to effectively prevent and control epidemic diseases. It is extremely important to prevent and treat common pig disea...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/715A61P31/04A61P31/12A61P33/00A61P31/14A61P31/20A61P37/04C08B37/00
CPCA61K31/715A61P31/04A61P31/12A61P33/00A61P31/14A61P31/20A61P37/04C08B37/0003A61K2300/00
Inventor 许启太
Owner HAINAN JINZHU AGRI DEV CO LTD
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