Extract with effect of alleviating smoking cessation symptoms, and preparation method and application of extract
A technology of extracts and symptoms, applied in the field of extracts with the effect of relieving smoking cessation symptoms and its preparation, can solve the problems that the nature of the action has not been elaborated, and achieve the effects of improving the success rate of smoking cessation, reducing withdrawal symptoms, and reducing pain
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Embodiment 1
[0023] Take Zanthoxylum bungeanum, use solvent (water: ethanol: ionic liquid = 2:90:8, volume ratio) to carry out cold soaking for 3 hours, then heat and reflux for extraction, the ratio of solid to liquid is 1:10, each extraction is 2 hours, after the sample is extracted twice The combined extracts are concentrated by a rotary evaporator and then dried to obtain the Zanthoxylum bungeanum extract. Take the above extract, add an appropriate amount of starch, mix evenly, granulate, pack into capsules, and make 1000 capsules to obtain the capsule oral medicine.
Embodiment 2
[0025] Get the Zanthoxylum bungeanum after extracting volatile oil, carry out countercurrent extraction with solvent (water: ethanol: deep eutectic solvent ([C4MIM][BF4])=10:85:5, volume ratio), solid-liquid ratio is 1:50, every time After extracting for 2 hours, the samples were extracted twice, and then the combined extract was concentrated by a rotary evaporator and then dried. Take the above-mentioned extract, add appropriate amount of starch and cyclodextrin, mix evenly, granulate and tablet, and make 1000 tablets to obtain the tablet oral medicine.
Embodiment 3
[0027] Take Zanthoxylum bungeanum, use solvent (water: ethanol: deep eutectic solvent [ChCl-lactic acid (1:2)] = 30:50:20, volume ratio) ultrasonically assisted extraction, the ratio of solid to liquid is 1:1, each extraction 1h , After the sample is extracted twice, the combined extract can be concentrated and then dried. The above-mentioned extract is taken, added into molten polyethylene glycol, stirred evenly, and made into a drop pill, and the oral medicine of the drop pill is obtained.
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