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Atomization combined medicine for treating cancer, and preparation method thereof

A drug and cancer technology, applied in the field of biomedicine, can solve problems such as damage to the lung mucosa, and achieve the effect of no toxic and side effects

Inactive Publication Date: 2020-12-29
曹赫扬
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

As a result, nebulized inhalation of anticancer drugs directly and severely damages the rapidly growing lung mucosa, so there is no anticancer western medicine that uses nebulized inhalation for treatment

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0016] Step ① Proportion by mass: Curcuma 60g, Forsythia 45g, Honeysuckle 45g, Sanwei dried medicinal materials weighing 150g in total, wash, add 600ml of water, soak at a temperature of 30-45°C for 30 minutes. Then add 200ml of acetone and 200ml of ethanol, and reflux at 56-68°C for 40 minutes. Then raise the temperature to 68-78°C, collect acetone and ethanol by fractional distillation under reduced pressure, and then filter out the liquid medicine to obtain about 350ml of liquid medicine;

[0017] Step ② According to mass ratio: 45g of Hedyotis diffusa, 45g of Scutellaria barbata, 20g of Donglingcao, 40g of Astragalus, 20g of Atractylodes macrocephala, 20g of turmeric, 25g of Prunella vulgaris, 15g of Pinellia chinensis, the total mass of the above dry medicinal materials is 230g. Wash, add 800-1000ml of cold water, bring to a boil, then simmer for 25-35 minutes, and filter out the first liquid medicine. Then add 500-600ml of water, bring to a boil, then simmer for 20-30 m...

Embodiment 2

[0020] Step ① Proportion by mass: Curcuma 35g, Forsythia 30g, Honeysuckle 25g, Sanwei dried medicinal materials weighing 90g in total, wash, add water 300ml, soak at a temperature of 30-40°C for 30 minutes. Then add 100ml of acetone and 100ml of ethanol, and reflux at 55-68°C for 30 minutes. First raise the temperature to 68°C to set aside acetone, then raise the temperature to 78°C to distill ethanol under reduced pressure, then cool to 45°C to filter out the liquid medicine, and obtain about 180ml of liquid medicine;

[0021] Step ② According to mass ratio: 30g of Hedyotis diffusa, 25g of Scutellaria barbata, 15g of Radix Radix Astragali, 20g of Astragalus, 10g of Atractylodes macrocephala, 15g of turmeric, 15g of Prunella vulgaris, 10g of Pinellia chinensis, and 140g of the above dried herbs. Wash, add 600ml of cold water, bring to a boil, then simmer for 25-30 minutes, and filter out the first liquid medicine. Then add 400ml of water, bring to a boil, then simmer for 20 m...

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PUM

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Abstract

The invention discloses an atomization combined medicine for treating cancer, and a preparation method thereof. The preparation method comprises the following steps of: (1), extracting volatile oil from 10-25 parts by weight of curcuma zedoary, 5-20 parts by weight of fructus forsythiae and 5-15 parts by weight of honeysuckle by using acetone, ethanol and water; (2), decocting and extracting 5-15parts by weight of oldenlandia diffusa, 5-15 parts by weight of sculellaria barbata, 3-10 parts by weight of rabdosia rubescens, 10-20 parts by weight of astragalus membranaceus, 5-10 parts by weightof atractylodes macrocephala, 5-10 parts by weight of turmeric, 5-10 parts by weight of selfheal and 3-10 parts by weight of rhizoma pinellinae praeparata in water; and (3), mixing the medicine liquidextracted in the step (1) and the medicine liquid extracted in the step (2), adding 1 / 5-1 / 10 of trichloromethane according to the weight, performing refluxing for 30-40 minutes, and distilling out redundant trichloromethane to obtain the required atomized medicine liquid. The medicine liquid prepared by the invention is volatilized by an atomizer, is directly delivered into each bronchus of the lung, and also can be delivered to blood through permeation and exchange of the bronchus of the lung and each capillary of the lung, so that the purpose of treating cancer is achieved; and meanwhile, anew way is provided for traditional cancer treatment.

Description

technical field [0001] The invention belongs to the technical field of biomedicine, and more specifically relates to an atomized combined drug for treating cancer and a preparation method thereof. Background technique [0002] Cancer is a major problem in medical research in the world today, which seriously threatens human health and life safety. According to statistics, the number of people suffering from cancer in the world is more than 17 million every year, and 4 million people in my country suffer from malignant tumors every year. Although there are many treatment options in the world at present, surgery, radiotherapy and chemotherapy, and targeted drugs are generally used as clinical treatment methods, but due to cancer cell metastasis, drug side effects, and drug resistance, the patient's physique is seriously damaged, and so far there is no cure for cancer. High-efficiency, broad-spectrum, non-toxic and side-effect specific drugs. However, traditional Chinese medic...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61K9/72A61P35/00
CPCA61K9/0078A61K9/12A61K36/284A61K36/355A61K36/481A61K36/53A61K36/536A61K36/539A61K36/634A61K36/748A61K36/8888A61K36/9066A61K2236/331A61K2236/333A61K2236/39A61P35/00A61K2300/00
Inventor 曹赫扬
Owner 曹赫扬
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