Composition containing silybum marianum extract and fructose 1, 6 diphosphate and application of composition in liver protection, sobering and fatigue resistance

Abstract

The invention discloses a composition. The composition contains a silybum marianum extract and fructose 1, 6 diphosphate or a derivative thereof, or a salt thereof. The silybum marianum extract is ina silybum marianum extract microcapsule form and / or a silybum marianum extract liposome form and / or a silybum marianum extract self-microemulsifying form, and the composition of the silybum marianum extract and FDP has the effects of reducing liver injury, preventing hangover and resisting fatigue, and particularly can quickly take effect to reduce liver injury and quickly sober up.

Description

technical field

[0001] The invention relates to a composition, in particular to a composition containing milk thistle extract and fructose 1,6 diphosphate for reducing liver damage and other effects and its application. Background technique

[0002] Milk thistle is an annual or biennial herb, native to southern Europe and North Africa, and has a history of thousands of years of cultivation and use in Europe and Africa. It is a folk medicinal plant. Milk thistle is widely used as a remedy for liver disease and cardiovascular disease.

[0003] Milk thistle extract is made from the dry fruit of milk thistle Silybummarianum, and commercial extracts are usually standardized to contain 80% of total silymarin. Silymarin is a complex mixture of polyphenols, including seven closely related flavonol-lignin adducts (silibinin A, silybin B, isosilibinin A, isosilibinin B, silymarin, isosilymarin and silymarin) and a flavonoid taxifolin. Silybin is a semi-purified fraction of silybin,...

Examples

Embodiment 1

[0038] A composition comprising milk thistle extract and sodium fructose-1,6-diphosphate, silybin (including silybin A and silybin B) in the milk thistle extract accounts for silybin 80% of the extract, milk thistle extract is in the form of milk thistle-phospholipid complex, milk thistle extract is 40% (w / w), sodium fructose-1,6-diphosphate is 60% (w / w).

Embodiment 2

[0040] A composition comprising milk thistle extract and sodium fructose-1,6-diphosphate, silybin in the milk thistle extract accounts for 70% of the milk thistle extract, and the milk thistle extract is milk thistle In the form of thistle-phospholipid complex, 20% (w / w) of milk thistle extract and 80% (w / w) of sodium fructose-1,6-bisphosphate.

Embodiment 3

[0042] A composition comprising milk thistle extract and sodium fructose-1,6-diphosphate, silybin in the milk thistle extract accounts for 90% of the milk thistle extract, and the milk thistle extract is milk thistle In the form of thistle-phospholipid complex, milk thistle extract was 33.3% (w / w) and sodium fructose-1,6-bisphosphate was 66.7% (w / w).

technical field

[0001] The invention relates to a composition, in particular to a composition containing milk thistle extract and fructose 1,6 diphosphate for reducing liver damage and other effects and its application. Background technique

[0002] Milk thistle is an annual or biennial herb, native to southern Europe and North Africa, and has a history of thousands of years of cultivation and use in Europe and Africa. It is a folk medicinal plant. Milk thistle is widely used as a remedy for liver disease and cardiovascular disease.

[0003] Milk thistle extract is made from the dry fruit of milk thistle Silybummarianum, and commercial extracts are usually standardized to contain 80% of total silymarin. Silymarin is a complex mixture of polyphenols, including seven closely related flavonol-lignin adducts (silibinin A, silybin B, isosilibinin A, isosilibinin B, silymarin, isosilymarin and silymarin) and a flavonoid taxifolin. Silybin is a semi-purified fraction of silybin,...

Examples

Embodiment 1

[0038] A composition comprising milk thistle extract and sodium fructose-1,6-diphosphate, silybin (including silybin A and silybin B) in the milk thistle extract accounts for silybin 80% of the extract, milk thistle extract is in the form of milk thistle-phospholipid complex, milk thistle extract is 40% (w / w), sodium fructose-1,6-diphosphate is 60% (w / w).

Embodiment 2

[0040] A composition comprising milk thistle extract and sodium fructose-1,6-diphosphate, silybin in the milk thistle extract accounts for 70% of the milk thistle extract, and the milk thistle extract is milk thistle In the form of thistle-phospholipid complex, 20% (w / w) of milk thistle extract and 80% (w / w) of sodium fructose-1,6-bisphosphate.

Embodiment 3

[0042] A composition comprising milk thistle extract and sodium fructose-1,6-diphosphate, silybin in the milk thistle extract accounts for 90% of the milk thistle extract, and the milk thistle extract is milk thistle In the form of thistle-phospholipid complex, milk thistle extract was 33.3% (w / w) and sodium fructose-1,6-bisphosphate was 66.7% (w / w).

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