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4results about How to "Improve mitochondrial function" patented technology

A nano-enzyme material, a preparation method and application thereof

The application belongs to the technical field of biological nanomaterials, and particularly relates to a nano-enzyme material and a preparation method and application thereof. The application reacts dimethyl imidazole and metal salt in an aqueous solution to obtain a metal-dimethyl imidazole composite material solution, wherein the metal salt comprises copper salt and / or zinc salt; and reacts the metal-dimethyl imidazole composite material solution and tannic acid to obtain a nano-enzyme material. The nano-enzyme material provided by the application has excellent antioxidant enzyme-like catalytic activity and good biocompatibility, can effectively remove abnormally increased reactive oxygen species (ROS) in the process of myocardial infarction and myocardial ischemia-reperfusion injury, inhibit inflammatory response and myocardial cell apoptosis, improve the mitochondrial function state, thereby promoting the repair of damaged myocardial tissue and significantly improving the cardiac function, and provides a new technical solution for the treatment of myocardial infarction and related ischemic cardiovascular diseases.
Owner:SHANXI MEDICAL UNIV

Spermidine composition for inhibiting aging of hair follicle stem cells and promoting growth period and application

PendingCN122005817Aprevent agingRestore youthful functionsOrganic active ingredientsCosmetic preparationsReactive oxygen radicalsProliferation activity
The invention discloses a spermidine composition for inhibiting aging of hair follicle stem cells and promoting growth period entry and application, and relates to the technical field of biological medicine and functional skin care. The invention discloses a spermidine composition for inhibiting aging of hair follicle stem cells and promoting growth period entry. The skin care product is prepared from the following components in parts by mass: 0.5 to 3 parts of spermidine, 0.2 to 2 parts of an autophagy activator, 0.5 to 4 parts of an antioxidant, 0.1 to 2 parts of a mitochondrial function accelerant, 0.2 to 3 parts of a microcirculation accelerant, 1 to 6 parts of a skin penetration accelerant, 0.2 to 1 part of a preservative, 0.05 to 0.4 part of a pH regulator and 60 to 95 parts of a carrier matrix. The composition can effectively reduce the aging rate of hair follicle stem cells and remarkably improve the proliferation activity of the hair follicle stem cells, active oxygen free radicals around the hair follicle stem cells can be effectively removed by adding the antioxidant of a novel structure, damage of external stimulation to hair follicles is reduced, and a systematic cell protection and repair mechanism is formed.
Owner:SHANGHAI ERGOTEIN BIOTECHNOLOGY GRP CO LTD

Application of microorganism-derived outer membrane vesicles in medicines for treating obesity and related metabolic diseases

The invention relates to application of microorganism-derived outer membrane vesicles in medicines for treating obesity and related metabolic diseases, and belongs to the technical field of exosomes. In order to solve the technical problems that probiotics beneficial to intestinal tracts are weak in colonization ability in the intestinal tracts, are easily influenced by gastrointestinal tract environments and are unstable in individual response, the sphingosine-containing microbe-sourced outer membrane vesicle is provided, and the sphingosine content in the outer membrane vesicle is 50-65 ng / mg.
Owner:SUN YAT SEN UNIVERSITY SHENZHEN +1

Composition acting on ovary somatic cell membrane structure and application thereof

PendingCN121846245AImprove ovarian functionImprove mitochondrial functionPeptide/protein ingredientsSexual disorderBiotechnologyCell membrane
The invention discloses a composition acting on an ovary somatic cell membrane structure and application of the composition. The composition acting on the ovary somatic cell membrane structure comprises the following components in parts by weight: 12-18 parts of a clove extract, 4-8 parts of a sophora flower bud extract, 8-12 parts of Chinese yam protein polypeptide, 4-8 parts of a cranberry extract and 8-12 parts of a citrus extract. The composition can act on an ovary somatic cell membrane structure to improve the mitochondrial function of oocytes, increase the number of the oocytes and reduce the fragment rate of the oocytes, so that the ovary function of elderly women is improved, and the purposes of improving the fertility and delaying senescence are achieved.
Owner:HAINAN LEYUN BIOTECHNOLOGY CO LTD