Formula and preparation method of purgative for improving detection sensitivity of dog tapeworm disease excrement

Abstract

The invention relates to a formula of a purgative for improving the detection sensitivity of dog tapeworm disease excrement. According to the the use amount for every Kg of weight of a dog, the purgative comprises 0.002-0.008 g of a tapeworm paralysis agent, 3-6 g of a quick purgation agent, 3-6 g of a binder and 9.2-20.4 g of a phagostimulant. The invention provides a preparation method of the purgative for improving the detection sensitivity of the dog tapeworm disease excrement. The preparation method comprises the following steps: weighing the components in the formula of the purgative for later use; mixing the tapeworm paralysis agent with the rapid purgation agent; and preparing a shell from the phagostimulant. By using the medicament provided by the invention, the average defecation time of dogs can be reduced by 2.75 times, and the sample obtaining efficiency is remarkably improved. According to the medicament provided by the invention, by paralyzing tapeworm bodies, the detection rate of a dog dung egg floating method can be increased by 1.24 times, the dog dung PCR (Polymerase Chain Reaction) detection rate is increased by 1.16 times, and the detection sensitivity is remarkably improved. In addition, the tapeworm paralysis agent, the rapid purgation agent and the like are wrapped by the phagostimulant, so that dogs can swallow the purgative without rejection, and the dogs are more convenient to feed.

Description

technical field [0001] The invention relates to the technical field of prevention and treatment of canine taeniasis, and more specifically relates to a cathartic formula for improving the detection sensitivity of canine taeniasis feces and a preparation method of the cathartic for improving the detection sensitivity of canine taeniasis feces. Background technique [0002] Echinococcus is a tapeworm belonging to the genus Echinococcus and Echinococcus. Its adults parasitize in canine carnivores, and its larvae (Echinococcus) parasitize in humans, various herbivorous livestock and other animals. A parasite that can cause severe zoonotic disease, usually called echinococcosis or echinococcosis in patients infected with larvae. [0003] Echinococcosis is widely distributed and has spread continuously with the development of world animal husbandry. It has become a global important public health and economic problem. The detection of echinococcus in dog feces (including PCR techn...

AI Technical Summary

Problems solved by technology

However, due to the low frequency of dog defecation, the efficiency of sample collection is affected. In addition, the content of Echinococcus eggs / worms in routine feces is low, which will affect the detection sensitivity and detection rate

In order to increase the total defecation volume of dogs (increase the volume of a single defecation or increase the frequency of defecation), laxatives are generally used, and conventional laxatives have their own peculiar smell. Canines have a sensitive sense of smell and do not like to swallow

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