Anti-hepatic fibrosis traditional Chinese medicine compound composition and application thereof

Abstract

The invention discloses an anti-hepatic fibrosis traditional Chinese medicine compound composition and application thereof The traditional Chinese medicine compound composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 10-30 parts of astragalus membranaceus, 10-30 parts of radix pseudostellariae, 5-15 parts of angelica sinensis, 5-15 parts of glossy privet fruit, 5-15 parts of poria cocos, 10-30 parts of roasted rhizoma atractylodis macrocephalae, 5-15 parts of pericarpium citri reticulatae, 5-15 parts of wine-processed scutellaria baicalensis and 3-10 parts of honey-fried licorice root. According to the pathogenesis of hepatic fibrosis, a syndrome differentiation and treatment method is adopted, a prescription is screened in combination with pharmacological experiments, and after the medicines in the prescription are scientifically compatible, the traditional Chinese medicine composition has a good liver protection effect on chronic and acute hepatic failure patients clinically, has a good prevention and treatment effect on hepatic fibrosis in vivo, inhibits proliferation of activated hepatic stellate cells in vitro, has the efficacy of preventing liver cell injury, has a good anti-hepatic fibrosis effect, is a promising traditional Chinese medicine compound, and has a good market promotion value.

Description

technical field [0001] The invention belongs to the technical field of medicine, and in particular relates to a traditional Chinese medicine compound with anti-hepatic fibrosis effect and application thereof. Background technique [0002] Liver fibrosis is a common pathological process in the development of various chronic liver diseases. Various reasons lead to excessive proliferation and abnormal deposition of extracellular matrix components in liver tissue, which in turn causes abnormal changes in liver structure or function. Dysfunction and failure seriously endanger life and health. Delaying or even reversing liver fibrosis is of great significance to reducing the occurrence of serious complications and improving the quality of life of patients. [0003] As the main organ of the disease, the liver has its own unique physiological characteristics. The body is yin and uses yang, which stores blood while the body yin conserves liver qi. The movement and transformation of...

AI Technical Summary

Problems solved by technology

However, currently there are different opinions on the syndrome differentiation and classification of liver fibrosis, there is no unified and standardized standard, and the syndromes are often combined, and there is no effective anti-hepatic fibrosis drug

Images