A preparation method of a partially gelatinized nasal cavity swelling hemostatic sponge

A hemostatic sponge and gelling technology, which can be used in medical formulations, surgery, coatings, etc., can solve the problems of slow sponge absorption and expansion, loss of rapid absorption and expansion, and poor wound adhesion. Rapid liquid absorption, low friction, good tensile and compressive strength

Active Publication Date: 2022-03-11
江苏申思生物科技有限公司
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  • Abstract
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  • Claims
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Problems solved by technology

[0007] The disadvantage of this method is that the functional coating is formed by the spraying process. If the coating is thin, because the polyvinyl alcohol sponge has a millimeter-scale pore size and an open-pore structure, the coating cannot completely fill the concave structure on the surface of the blank to obtain a flat surface. , resulting in poor adhesion to the wound, limited friction reduction when inserted or removed
If the coating is thicker, a dense rubber film layer will be formed, which will cause the sponge to absorb liquid and expand slowly, and lose the function of rapid liquid absorption and expansion.

Method used

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  • A preparation method of a partially gelatinized nasal cavity swelling hemostatic sponge
  • A preparation method of a partially gelatinized nasal cavity swelling hemostatic sponge

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Embodiment Construction

[0031] The following will clearly and completely describe the technical solutions in the embodiments of the present invention with reference to the accompanying drawings in the embodiments of the present invention. Obviously, the described embodiments are only some, not all, embodiments of the present invention. Based on the embodiments of the present invention, all other embodiments obtained by persons of ordinary skill in the art without making creative efforts belong to the protection scope of the present invention.

[0032] This embodiment provides a method for preparing a nasal swelling hemostatic sponge whose surface can be partially gelled, comprising the following steps:

[0033] (1). Preparation of scaffold membrane

[0034] In a 1000ml beaker, add 500ml of alcohol, 5g of propylene glycol, 0.5g of fatty alcohol polyoxyethylene ether, 10g of ethyl cellulose, and 3g of chitosan micropowder, and stir thoroughly for 30 minutes to obtain ethyl cellulose-based membrane solu...

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Abstract

The invention discloses a preparation method of a partially gelatinized nasal cavity swelling hemostatic sponge on the surface, which comprises such steps as preparation of base frame membrane, modification of base frame membrane, surface coating treatment, solvent replacement, phase separation and pore formation, etc. Drying, compression, assembly, packaging, and sterilization can be completed; the surface of the sponge made by this method is smooth, and the friction force is small; and the surface smooth layer has a microporous structure, which is liquid-permeable and air-permeable; Gelled swelling, stable mechanical properties, can form a wound protective layer; part of the gelled swelling layer is integrated with the main body of the sponge and cannot be separated, when taken out together, there is no residue; the product can be applied to nasal cavity hemostatic sponges, and can also be used on wounds Nursing dressings and sponge cervical dilators and other medical devices.

Description

technical field [0001] The invention relates to the field of sponge dressings, in particular to a preparation method of a compressed expandable sponge dressing whose surface can be partially gelled, especially a preparation method of a nasal cavity swelling hemostatic sponge whose surface can be partially gelled. Background technique [0002] Traditional nasal hemostatic materials such as vaseline gauze can effectively play a role in mechanical compression and support, but they have serious defects, such as the possibility of slipping into the pharynx during packing, causing discomfort, and severe swelling and pain around the nasal cavity after packing, and extraction is easy to cause Secondary bleeding, resulting in secondary infection. The most unbearable thing for patients is that the extraction of gauze is extremely painful, and even collapse and shock may occur. [0003] Expandable hemostatic sponge product is a clinical product that can quickly absorb liquid, compress...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): C08J9/36C08J9/40C08L29/04A61L24/00A61L24/06A61L24/08A61L24/10
CPCC08J9/365C08J9/40A61L24/08A61L24/108A61L24/06A61L24/0036A61L24/001A61L24/0015C08J2329/04C08J2401/28C08J2405/08C08J2429/14A61L2400/04A61L2300/232A61L2300/41A61L2300/418C08L5/04C08L5/08C08L1/28C08L89/00C08L29/14
Inventor 谭明宁钟巧媛胡鹏岑必福宋祖权桑雨青
Owner 江苏申思生物科技有限公司
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