Application of belinostat in preparation of medicine for preventing, relieving and/or treating multiple sclerosis

A multiple sclerosis, belistat technology, used in the field of medicine
CN112972448AActive Publication Date: 2021-06-18INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI +1
2 Cites 0 Cited by

Patent Information

Authority / Receiving Office
CN Β· China
Patent Type
Applications(China)
Current Assignee / Owner
INST OF MATERIA MEDICA CHINESE ACAD OF MEDICAL SCI
Publication Date
2021-06-18

Smart Images

  • Figure 1
    Figure 1
  • Figure 2
    Figure 2
  • Figure 3
    Figure 3
Patent Text Reader

Abstract

The invention discloses application of belinostat in preparation of a medicine for preventing, relieving and / or treating multiple sclerosis. In a mouse experimental autoimmune encephalomyelitis model, belinostat shows a good treatment effect, and can effectively treat pathological changes and progression of diseases. The therapeutic effect is achieved by inhibiting proliferation of microglial cells in a central nervous system.
Need to check novelty before this filing date? Find Prior Art

Description

technical field

[0001] The invention relates to the application of belistat in the preparation of drugs for preventing, alleviating and / or treating multiple sclerosis, and belongs to the technical field of medicine. Background technique

[0002] Multiple sclerosis (MS) is an autoimmune disease characterized by inflammatory demyelinating lesions of the central nervous system, which has the characteristics of high recurrence and disability. Clinical manifestations include paralysis, numbness, cramps, aphasia, and visual impairment. Epidemiological studies have shown that 50-300 people in every 100,000 people suffer from multiple sclerosis, and there are 2.3 million people in the world suffering from multiple sclerosis, mainly concentrated in European and American countries. The prevalence of multiple sclerosis increases with latitude, and the incidence of multiple sclerosis in women is twice that of men (Neurology.2014; 83(11):1022-1024). The etiology of multiple sclerosis i...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More