Experimental animal trachea instillation device

Abstract

The invention discloses an experimental animal trachea instillation device. The device comprises an operation table board, the inclination angle of the operation table board is adjustable, the operation table board is provided with an upper incisor fixing mechanism, a lower incisor fixing mechanism, a negative pressure tongue pressing mechanism and a trachea cannula and instillation mechanism, the trachea cannula and instillation mechanism comprises a hollow trachea cannula needle, the tail part of the trachea cannula needle is connected with a trachea cannula grip, the tail part of the trachea cannula grip is connected with a trachea cannula connecting tube, and the tail end of the trachea cannula connecting tube extends into a trachea cannula indicator; and the tracheal intubation needle is detachably connected with the tracheal intubation grip, and the tail part of the tracheal intubation needle can be connected with a liquid injector. The whole device can complete all operations only by one person, and is simpler to operate, high in success rate and superior to the previous operation needing cooperation of multiple persons; and meanwhile, operation is convenient and rapid, consumed time is short, and the success rate is high.

Description

technical field [0001] The invention relates to an experimental animal tracheal instillation device. Background technique [0002] Exposure through the respiratory tract is an important exposure route in scientific research fields such as toxicology and clinical medicine. Commonly used methods of respiratory exposure include intranasal instillation, exposed tracheal instillation and non-exposed tracheal instillation. The operation of intranasal instillation is simple, but the infusion solution needs to be instilled into the nasal cavity drop by drop, which takes a long time to operate, and the infusion solution may reach the stomach through the esophagus, resulting in inaccurate dosage. The exposed tracheal instillation requires general anesthesia and exposure of the trachea. Although the success rate is high and the infusion volume is accurate, the surgical incision will increase the risk of trauma and infection. Non-exposed tracheal instillation does not require surgical...

AI Technical Summary

Problems solved by technology

The methods of non-exposed tracheal instillation include: transmitted light intubation, blind intubation, use of magnifying glass, endoscope and other auxiliary intubation methods, but most of these methods require special equipment. For small mammals (such as mice or rats), due to the anatomy of the oral cavity and pharynx, intubation is more difficult, and the operation skills are relatively high, requiring the cooperation of multiple people

Chinese patent CN209827080U discloses a fixation device for experimental mice used for non-exposed tracheal instillation. However, in this patent, only the fixation of mice can be realized, and there is also unreliable fixation in the fixation, which cannot be applied to various body types. mice, and at least one person is required to cooperate, it takes 2 minutes to complete the operation, low efficiency, low reliability, and low safety

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