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Traditional Chinese medicine composition for treating thin endometrial hypomenorrhea as well as preparation method and application thereof

A technology of endometrium and composition, which is applied in the field of traditional Chinese medicine composition, can solve the problems of ineffectiveness and other problems, and achieve the effect of convenient taking, controllable process, and increasing menstrual flow

Active Publication Date: 2021-06-25
NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Most modern TCM doctors believe that the root cause of this disease is deficiency of liver and kidney yin and deficiency of qi and blood. Blindly adopting the method of nourishing liver and kidney qi and blood has little effect

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0025] 1. A traditional Chinese medicine composition for treating thin endometrial hypomenorrhea and infertility, which is made of the following raw materials in parts by weight:

[0026] 10g roasted tortoise shell, 10g roasted turtle shell, 10g rehmannia glutinosa, 10g cornus, 10g fried white peony root, 10g fried angelica, 10g Chuanxiong, 15g jujube seed, 10g roasted Anemarrhena, 10g Yun Fuling, 15g fried dangshen, 10g fried Atractylodes macrocephala .

[0027] 2. A method for preparing a traditional Chinese medicine composition for treating thin endometrium with low menstrual flow and infertility, comprising the following steps:

[0028] Take 10g of roasted tortoise shell and 10g of roasted turtle shell, add 10 times the amount of water and cook for 10 minutes, then add 10g of rehmannia glutinosa, 10g of cornus, 10g of fried white peony, 10g of fried angelica, 10g of chuanxiong, 15g of jujube seed, and roasted Mother 10g, Yun Fuling 10g, stir-fried Codonopsis 15g, fried At...

Embodiment 2

[0030] 1. A traditional Chinese medicine composition for treating thin endometrial hypomenorrhea and infertility, which is made of the following raw materials in parts by weight:

[0031] 60g roasted tortoise shell, 60g roasted turtle shell, 60g rehmannia glutinosa, 90g cornus, 60g fried white peony root, 30g fried angelica, 90g Chuanxiong, 90g jujube seed, 90g roasted Anemarrhena, 60g Yun Fuling, 60g fried Codonopsis pilosula, 120g fried Atractylodes macrocephala .

[0032] 2. A method for preparing a traditional Chinese medicine composition for treating thin endometrium with low menstrual flow, comprising the following steps:

[0033] Take 60g of roasted tortoise shell, 60g of roasted turtle shell, 60g of Rehmannia glutinosa, 90g of cornus, 60g of fried white peony, 30g of fried angelica, 90g of Chuanxiong, 90g of jujube seed, 90g of Zhimu, 60g of Yun Fuling, 60g of fried Codonopsis, and fried Atractylodes macrocephala. 120g, add 2 times the amount of water to soak for 1 hour...

Embodiment 3

[0035] 1. A traditional Chinese medicine composition for treating thin endometrial hypomenorrhea and infertility, which is made of the following raw materials in parts by weight:

[0036] 30g roasted tortoise shell, 30g roasted turtle shell, 30g rehmannia glutinosa, 45g cornus, 30g fried white peony, 15g fried angelica, 45g Chuanxiong, 45g jujube seed, 45g roasted Anemarrhena, 30g Yun Fuling, 30g fried Codonopsis, 60g fried Atractylodes macrocephala .

[0037] 2. A method for preparing a traditional Chinese medicine composition for treating thin endometrium with low menstrual flow and infertility, comprising the following steps:

[0038] First, take 30g of roasted tortoise shell, 30g of roasted turtle shell, 30g of Rehmannia glutinosa, 45g of cornus, 30g of fried white peony, 15g of fried angelica, 45g of Chuanxiong, 45g of Suanzaoren, 45g of Zhimu, 30g of Yun Fuling, 30g of fried Codonopsis and fried Atractylodes macrocephala 60g, add 2 times the amount of medicinal material...

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PUM

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Abstract

The invention discloses a traditional Chinese medicine composition for treating hypomenorrhea and infertility caused by thin endometrium and a preparation method thereof. The traditional Chinese medicine composition is prepared from 1-6 parts of roasted tortoise plastron, 1-6 parts of roasted turtle shell, 16 parts of prepared rehmannia root, 1-9 parts of pulp of dogwood fruit, 1-6 parts of parched white peony root, 0.5-3 part of fried angelica sinensis, 1-9 parts of ligusticum wallichii, 1.5-9 parts of spina date seed, 1-9 parts of roasted rhizoma anemarrhenae, 1-6 parts of poria cocos in Yunnan, 1-6 parts of fried codonopsis pilosula and 1-12 parts of roasted rhizoma atractylodis macrocephalae. A formula is screened through a large number of clinical researches, and a research result shows that the traditional Chinese medicine composition can effectively improve the syndromes of kidney yin deficiency type hypomenorrhea and infertility, increase the menorrhea, promote endometrial hyperplasia and follicle development in the later menstruation period, improve the levels of serum E2 and LH in the ovulation period, improve the levels of E2 and P in the middle luteal stage, increase the thickness of the endometrium in the middle-stage luteum, increase the volume of the endometrium and enrich blood perfusion under the endometrium in the middle-stage luteum, so that the endometrium receptivity is improved, embryo implantation is promoted to help pregnancy, and the traditional Chinese medicine composition is free of toxic and side effects and safe and reliable in medication.

Description

technical field [0001] The invention relates to a traditional Chinese medicine composition, in particular to a traditional Chinese medicine composition for treating thin endometrial menstrual bleeding and its application. Background technique [0002] Thin endometrium (Thin Endometrium, TE) is a common gynecological disease in recent years. The definition of this disease in modern medicine has not been clearly unified. If the membrane thickness is less than 7mm, the main clinical manifestations are normal menstrual cycle, or late menstruation, but too little menstrual flow (<20mL). Studies have shown that when the thickness of the endometrium is less than 6 mm, that is, below the threshold for obtaining pregnancy, the probability of pregnancy will decrease sharply. With the continuous improvement of assisted reproductive technology, thin endometrium is still one of the main reasons for clinical embryo transfer failure and pregnancy rate decline, and it is also an importa...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8964A61P15/00A61P15/08A61K35/586
CPCA61K35/586A61K36/804A61K36/40A61K36/71A61K36/65A61K36/232A61K36/236A61K36/725A61K36/8964A61K36/076A61K36/344A61K36/284A61P15/00A61P15/08A61K2236/331A61K2236/39A61K2236/53A61K2236/51A61K2300/00
Inventor 周惠芳周维叶刘贝胡明慧
Owner NANJING UNIVERSITY OF TRADITIONAL CHINESE MEDICINE
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