Symmetrical encryption method for DNA storage

A symmetric encryption, DNA molecule technology, applied in the field of systems biology research, can solve the problems of uneven DNA molecular sequence amplification, limited DNA storage biochemical characteristics, DNA sequence loss, etc. In addition, the effect of increasing the sequencing depth

Active Publication Date: 2021-08-27
GUANGZHOU UNIVERSITY
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  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

[0003]Although DNA storage has many advantages compared with traditional storage technologies, DNA storage itself is limited by biochemical characteristics and faces some problems: 1) DNA molecular sequence amplification is not Uniformity will cause some DNA sequences to be lost; 2) There are base insertion, deletion and substitution errors in the DNA sequence during synthesis and sequencing

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  • Symmetrical encryption method for DNA storage
  • Symmetrical encryption method for DNA storage
  • Symmetrical encryption method for DNA storage

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Embodiment Construction

[0041] Embodiments of the present invention are described in detail below, and examples of the embodiments are shown in the drawings, wherein the same or similar reference numerals denote the same or similar elements or elements having the same or similar functions throughout. The embodiments described below by referring to the figures are exemplary only for explaining the present invention and should not be construed as limiting the present invention. For the step numbers in the following embodiments, it is only set for the convenience of illustration and description, and the order between the steps is not limited in any way. The execution order of each step in the embodiments can be adapted according to the understanding of those skilled in the art sexual adjustment.

[0042] The technical solution of the present application provides a symmetrical DNA storage encryption method based on the idea of ​​information modulation. This method first uses the key to convert the compu...

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Abstract

The invention provides a symmetric encryption method for DNA storage, and the method comprises the following steps: obtaining a to-be-encrypted file, encrypting the binary information of the to-be-encrypted file according to an encryption key, and obtaining a DNA storage sequence; carrying out confusion operation processing on the DNA storage sequence; synthesizing the plurality of DNA storage sequences processed by the confusion operation to obtain a DNA molecular sequence, storing the DNA molecular sequence, sequencing the DNA molecular sequence to obtain a read length, and decrypting according to the read length and the encryption key to obtain binary information. According to the method, under different error rates, the sequencing depth is increased, the data recovery rate is in a rising trend, the information redundancy in the encryption and decryption process can be effectively reduced, the robustness is higher, the malicious cracking difficulty is large, the confidentiality effect is better, and the method can be widely applied to the technical field of system biology research.

Description

technical field [0001] The invention relates to the technical field of systems biology research, in particular to a symmetric encryption method for DNA storage. Background technique [0002] With the development of cloud computing technology and big data technology, the demand for human data storage shows an exponential growth trend. According to the forecast of the International Data Corporation, the total amount of data generated by humans will reach 175ZB in 2025. The storage requirements of massive data pose severe challenges to today's storage technologies (discs, hard drives, etc. based on electromagnetic principles) in terms of maintenance costs, service life, and data reliability. At the same time, DNA carrying genetic information has gradually attracted people's attention because of its high density, low energy consumption, and long storage life. In recent years, DNA storage has become a hot topic in interdisciplinary research. [0003] Although DNA storage has m...

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): H04L9/06H04L9/08G06F21/60G16B30/00
CPCH04L9/0618H04L9/0819G06F21/602G16B30/00
Inventor 刘文斌昝乡镇姚祥宇李树栋许鹏方刚陈智华石晓龙鲍振申
Owner GUANGZHOU UNIVERSITY
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