Synthesis process of pyraclostrobin

Abstract

The invention discloses a synthesis process of pyraclostrobin, relates to the field of kresoxim-methyl, and aims to solve the problems of low preparation efficiency, low process purity and influence on finished product quality of the existing kresoxim-methyl in the prior art. The synthesis process comprises the steps of: S1, preparing a kresoxim-methyl raw material through mixing in a reaction kettle; S2, preparing a water suspending agent through a superfine grinding method; S3, preparing a catalyst; S4, introducing the kresoxim-methyl raw material, the water suspending agent and the catalyst into a reaction kettle, and mixing to form an alkaline mixture; S5, heating, adding and dissolving ethanol into the mixture, reducing the pressure of the alkaline mixture, concentrating under reduced pressure, and recrystallizing; S6, after recrystallization, introducing nitrogen into the reaction kettle for cleaning, slowly dropwise adding a sodium methoxide solution after cleaning, and distilling after the reaction is finished to obtain a residue mixture; S7, uniformly spraying a potassium hydroxide aqueous solution into the mixture, and standing; and S8, after standing, carrying out solid-liquid separation on the mixture, and melting a solid phase at high temperature to obtain pyraclostrobin.

Description

technical field [0001] The invention relates to the technical field of kysstrobin, in particular to a synthesis process of pyraclostrobin. Background technique [0002] Kresoxim-methyl is a methoxyacrylate fungicide with high efficiency and broad spectrum. It has good effect on almost all fungal diseases such as powdery mildew, rust, glume blight, net spot, downy mildew, rice blast, etc. active. It can be used for stem and leaf spray, seed treatment, and soil treatment. It is mainly used for grain, rice, peanut, grape, potato, fruit tree, vegetable, coffee, lawn, etc. The dosage is 25ml-50 / mu. Kresoxim-methyl cannot be mixed with insecticide EC, especially organophosphorus EC, nor can it be mixed with organosilicon synergists, because it will cause phytotoxicity due to excessive penetration and spreading. [0003] However, the preparation efficiency of the existing kysstrobin is poor, the process purity is low, and the quality of the finished product is affected; therefor...

AI Technical Summary

Problems solved by technology

[0004] The purpose of the present invention is to provide a synthesis process of pyraclostrobin to solve the problems of poor preparation efficiency of the existing kresoxim-methyl proposed in the above background technology, low process purity and affecting the quality of finished products