Traditional Chinese medicine formula for promoting calcium supplement of postpartum women

Abstract

Aiming at postpartum osteoporosis, key gene targets of postpartum female osteoporosis are mined by using a life big data technology from an etiological mechanism, key compounds for regulating and controlling the key gene targets are found through a network pharmacological system tool, and medicinal and edible traditional Chinese medicines are screened on the basis to form a traditional Chinese medicine formula for promoting postpartum female calcium supplement. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 5-30 parts of Chinese yam, 2-20 parts of raspberry, 3-20 parts of fructus alpiniae oxyphyllae, 2-15 parts of gordon euryale seed, 5-40 parts of phaseolus calcaratus and 5-30 parts of lily. The traditional Chinese medicine formula performs multi-dimensional systematic regulation and control on osteoporosis caused by special physiology of postpartum women, is formed by combining a target-compound-traditional Chinese medicine corresponding relation, is clear in action mechanism, and effectively promotes calcium absorption when being taken independently or used in cooperation with a calcium preparation.

Description

technical field [0001] The invention belongs to the field of traditional Chinese medicines, and in particular relates to a traditional Chinese medicine prescription for promoting calcium supplementation of postpartum women. Background technique [0002] Women around the age of 30 are the bone peak formation period, and this stage is also the peak childbirth period. The substances needed for the growth of fetuses and newborns depend on the mother's supply, among which calcium and other minerals need to be provided by the mother. If calcium cannot be supplemented in time after delivery, it will not only affect the calcium content of milk and affect the development of newborns, but also easily lead to complications such as postpartum osteoporosis. [0003] At present, the most commonly used method of postpartum calcium supplementation is to take calcium supplement products. However, the current calcium supplement products are simply adding exogenous calcium (or adding vitamin ...

AI Technical Summary

Problems solved by technology

These calcium supplement products are only designed from the perspective of calcium absorption, and none of them supplement calcium according to the physiological characteristics and molecular mechanism of postpartum women, and cannot fundamentally solve the calcium deficiency problem of postpartum women

The most suitable drug prescription was not screened from the molecular mechanism of postpartum osteoporosis, which lacked scientificity and effectiveness

[0005] In addition, the national food safety standard "Standards for the Use of Food Nutritional Fortifiers" (GB 14880—2012) stipulates that the amount of calcium added to beverages is 160 mg / kg - 1350 mg / kg. At present, the daily consumption of liquid foods related to calcium preparations in China About 100mL, the maximum amount of calcium added according to laws and regulations is only 135 mg, which is far below the daily calcium intake requirement of 1200-1500mg / day for postpartum women, and the effect of calcium supplementation on postpartum women is negligible. This problem also exists with kind food

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