White blood cell detection and identification method, device, computer storage medium and electronic equipment

An identification method and white blood cell technology, which is applied in the field of devices, white blood cell detection and identification methods, computer storage media and electronic equipment, can solve the problems of cumbersome and boring operations, low accuracy of manual statistical results, misdiagnosis, etc., and achieve objective and stable results. Time-consuming inspection and comprehensive statistical results

Active Publication Date: 2022-07-22
BEIJING XIAOYING TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] However, the manual microscope inspection operation is not only time-consuming, but not suitable for the screening of large batches of specimens; moreover, due to the influence of the experience of the cytomorphological test workers and the number of jobs, the objectivity of the judgment results will be insufficient. Resulting false-negative results may cause patients to miss treatment or even misdiagnose
[0006] Therefore, the existing white blood cell detection and identification methods have the following problems: (1) manual counting of white blood cells under a microscope is inefficient, and the operation is cumbersome and boring; (2) the accuracy of manual statistical results is low, and it is easily interfered by subjective experience and human factors

Method used

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  • White blood cell detection and identification method, device, computer storage medium and electronic equipment
  • White blood cell detection and identification method, device, computer storage medium and electronic equipment
  • White blood cell detection and identification method, device, computer storage medium and electronic equipment

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Embodiment 1

[0087] Embodiments of the present invention provide a method for detecting and identifying white blood cells, such as figure 1 As shown, the method includes:

[0088] S100: Perform full-field photography on several blood slide samples to obtain multiple single-field image samples of blood slides.

[0089] In this step, a large number of blood slide samples are firstly photographed in a full field of view using a slide scanner or a microscope camera system, and digitally processed to obtain multiple single-field image samples of blood slides to form a slide scanning image group.

[0090] Specifically, firstly, the collected blood sample is pushed onto the slide to obtain a blood slide, and then a full-field blood picture is taken using a slide scanner based on automated technology or a microscope camera system based on manual adjustment.

[0091] In the process of full field of view imaging, the innovations of the present invention are firstly the image stitching technology ba...

Embodiment 2

[0177] Embodiments of the present invention provide a white blood cell detection and identification device, such as Figure 7 As shown, the device includes:

[0178] The sample acquisition module 1 is used to perform full-field photography on several blood slide samples to obtain multiple single-field image samples of blood slides.

[0179] The image restoration model training module 2 is used to obtain a first training set and a first verification set based on multiple single-view image samples of blood slides, and train an image restoration model constructed based on the first training set and the first verification set.

[0180] Image segmentation and multi-task classification model training module 3 is used to select multiple single-view image samples of blood slides with uniform distribution of white blood cells from multiple single-view image samples of blood slides, and select multiple single-view image samples of blood slides The location and category of the white blo...

Embodiment 3

[0219] The method described in Embodiment 1 provided by the present invention can implement business logic through a computer program and record it on a storage medium, and the storage medium can be read and executed by a computer to achieve the effects of the solution described in Embodiment 1 of this specification. Therefore, the present invention also provides a computer storage medium for leukocyte detection and identification, including a memory for storing processor-executable instructions, when the instructions are executed by the processor, the instructions include the steps of the leukocyte detection and identification method of Embodiment 1.

[0220] The storage medium may include a physical device for storing information, usually after digitizing the information and then storing it in a medium using electrical, magnetic or optical means. The storage medium may include: devices that use electrical energy to store information, such as various memories, such as RAM, ROM...

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Abstract

The invention discloses a white blood cell detection and identification method, device, computer storage medium and electronic equipment, belonging to the field of blood cell detection. The present invention firstly performs full-field photography on a large number of blood slides to establish a slide scan image group. The training and validation datasets were prepared for the image restoration model, image segmentation and multi-task classification model, respectively, from the set of slide scan images. Using deep learning and convolutional neural network technology for model training, and optimizing the model through continuous parameter tuning and error analysis, the final image restoration model, image segmentation and multi-task classification model are obtained. During the application process, the blood glass slide to be tested is also subjected to full-field photography to establish a slide scan image. The restored clear slide scan image is obtained through the image restoration model, and the location and category of the white blood cells are obtained through image segmentation and multi-task classification model. The invention can quickly, comprehensively, accurately and objectively realize the detection and identification of white blood cells.

Description

technical field [0001] The invention relates to the field of blood cell detection, in particular to a white blood cell detection and identification method, device, computer storage medium and electronic equipment. Background technique [0002] Blood cells are roughly divided into three categories: red blood cells, white blood cells, and platelets, and white blood cells include various subtypes. In the field of biological analysis, especially in the field of clinical test analysis, accurate detection and identification of different subtypes of leukocytes plays a very important role in diagnosis and research, and the changes in the content of each subtype of leukocytes are clinically used for diagnosis and treatment. important indicators. [0003] The current blood testing process in the hospital is: blood sample—blood analyzer—dyeing machine—manual microscopic examination. The whole process takes 60 minutes. Blood samples are obtained by manually drawing blood from patients...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): G06V10/774G06V10/764G06K9/62G06N3/04G06N3/08G06T5/00G06T5/50G06T7/10
CPCG06T5/001G06T5/50G06T7/10G06N3/08G06T2207/20081G06T2207/20084G06T2207/10056G06N3/044G06N3/045G06F18/24G06F18/214
Inventor 连荷清李柏蕤方喆君
Owner BEIJING XIAOYING TECH CO LTD
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