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Appliance

A technology for utensils and containers, applied in laboratory utensils, biochemical instruments, laboratory containers, etc., can solve problems such as high operating costs, operator errors, and pollution

Pending Publication Date: 2022-07-29
ORIBIOTECH LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] A current problem in the production of cell or gene therapy for medical use is the lack of compact, automated closed systems to perform contamination-free unit operations
For example, during cell culture, upstream or subsequent processing of cells, there is a risk of contamination when additions are made to culture vessels, or when cells are removed or liquid samples are removed
Current operating systems are largely manual and therefore expensive to operate
Often multiple pieces of equipment are required to cover all non-cell culture steps, which involves many transfers, each of which can lead to operator error and contamination
[0008] Additionally, as manual operations increase, so does the risk of manual error, so current labor-intensive processes may lack the robustness needed to manufacture clinical-grade therapeutics

Method used

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Examples

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Embodiment Construction

[0150] The described exemplary embodiments relate to an apparatus for introducing or removing material directly into a container. Other embodiments relate to systems and methods for manually or in a semi-automatic or automatic manner to introduce or remove material from a container. Further embodiments, examples, aspects and advantages will become apparent from the remaining description.

[0151] Certain terms are used in the following description for convenience only and not limitation. The terms "upper" and "lower" refer to the directions of reference in the drawings and are relative to the components described when assembled and installed. The words "inner", "inward" and "outer" and "outward" refer to directions towards and away, respectively, towards and away from a designated centerline or geometric center (eg, a central axis) of the described element, the specific meaning being clear from the context of the specification clear. Furthermore, the terms "proximal" (ie, n...

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Abstract

The present invention relates to an appliance suitable for treating biological material for directly introducing material into or removing material from a container, the appliance comprising: a body comprising at least one resealable port; comprising an aperture, where the cap is disposed on an upper side of the body, and the cap is movable such that the aperture of the cap is configured to expose at least a portion of the resealable port.

Description

technical field [0001] The present invention relates to a device for introducing material directly into or removing material from a container. The apparatus described herein is suitable for processing biological materials, especially for one or more unit operations in cell processing such as cell and / or gene therapy manufacturing. Furthermore, the present invention relates to systems and methods of using the appliances described herein. Background technique [0002] Cell and gene therapy (CGT) manufacturing processes are often complex and include manual or semi-automated steps for multiple devices. A system of equipment used in various steps or unit operations of cell-based therapeutic product (CTP) manufacture may include devices for various unit operations. For example, unit operations may include cell collection, cell isolation, selection, cell expansion, cell washing, volume reduction, cell storage or transport. Unit operations can vary widely based on the manufacturi...

Claims

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Application Information

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IPC IPC(8): C12M1/00C12M1/12
CPCC12M23/38C12M37/04B01L3/523B01L3/563B01L2200/02B01L2300/045C12M23/58B01L3/502715B01L2200/026B01L2200/0689B01L2300/046
Inventor 法伦·韦莱奇威廉·雷姆斯理查德·史密斯尼尔·利滕迈克尔·索福德
Owner ORIBIOTECH LTD
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