Compound formulation for treating hypertension

Abstract

The present invention discloses one kind of hypertension treating compound preparation. The compound preparation contains Indapamide in 0.5-2.5 mg and Celiprolol in 25-200 mg as daily dosage. Compared with the single component hypertension treating medicine with relatively great dosage, the present invention has superior blood pressure lowering effect, no negative effect caused by some one medicine component, no compensated reaction, increased patient's tolerance and raised compliance.

Description

technical field

[0001] The invention relates to a compound preparation for treating hypertension. Background technique

[0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. In 1991, my country conducted a sample survey of 940,000 people over the age of 15. Statistics show that the prevalence of hypertension in my country has reached 11.26%, which is 25% higher than that in the 10 years from 1979 to 1980. There are more than 130 million hypertensive patients in my country. . Moreover, this upward momentum continues. Statistics also show that the treatment rate of hypertension is 17.4% in urban areas and 5.4% in rural areas; the control rate (systolic blood pressure<140mmHg and diastolic blood pressure<90mmHg after treatment) is only 2.9%. From the above statistics, it can be seen that the prevalence of hypertension in my country is constantly increasing, but the treatment rate and control rate are low, forming a h...

Examples

Embodiment 1

[0037] A combination preparation containing the following daily doses of the ingredients:

[0038] Indapamide 1.25mg

[0039] Celery Lol 50mg

[0040] Microcrystalline Cellulose 20mg.

[0041] This embodiment can be made into compound indapamide-celiprolol tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

[0042] The preparation method of the compound preparation of the following examples is the same as Example 1.

Embodiment 2

[0044] A combination preparation containing the following daily doses of the ingredients:

[0045] Indapamide 1.25mg

[0046] Celery Lol 100mg

[0047] Low-substituted hydroxypropyl cellulose 10mg.

Embodiment 3

[0049] A combination preparation containing the following daily doses of the ingredients:

[0050] Indapamide 2.5mg

[0051] Celery Lol 25mg

[0052] Pregelatinized starch 30mg.

technical field

[0001] The invention relates to a compound preparation for treating hypertension. Background technique

[0002] Hypertension is the most common cardiovascular disease and a major public health problem worldwide. In 1991, my country conducted a sample survey of 940,000 people over the age of 15. Statistics show that the prevalence of hypertension in my country has reached 11.26%, which is 25% higher than that in the 10 years from 1979 to 1980. There are more than 130 million hypertensive patients in my country. . Moreover, this upward momentum continues. Statistics also show that the treatment rate of hypertension is 17.4% in urban areas and 5.4% in rural areas; the control rate (systolic blood pressure<140mmHg and diastolic blood pressure<90mmHg after treatment) is only 2.9%. From the above statistics, it can be seen that the prevalence of hypertension in my country is constantly increasing, but the treatment rate and control rate are low, forming a h...

Examples

Embodiment 1

[0037] A combination preparation containing the following daily doses of the ingredients:

[0038] Indapamide 1.25mg

[0039] Celery Lol 50mg

[0040] Microcrystalline Cellulose 20mg.

[0041] This embodiment can be made into compound indapamide-celiprolol tablet, and the preparation method can adopt the preparation method of common pharmaceutical preparations.

[0042] The preparation method of the compound preparation of the following examples is the same as Example 1.

Embodiment 2

[0044] A combination preparation containing the following daily doses of the ingredients:

[0045] Indapamide 1.25mg

[0046] Celery Lol 100mg

[0047] Low-substituted hydroxypropyl cellulose 10mg.

Embodiment 3

[0049] A combination preparation containing the following daily doses of the ingredients:

[0050] Indapamide 2.5mg

[0051] Celery Lol 25mg

[0052] Pregelatinized starch 30mg.

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