Medical coating powder containing nano material

Abstract

The medicinal coating powder containing nanometer material consists of hydromellose 55-65 wt%, copolymer of vinyl pyrrolidone and vinyl acetate 8 wt%, glycerin 15 wt%, Span 8 wt%, coloring agent 2-4 wt%, and nanometer titania 2-10 wt%. The medicinal coating powder containing nanometer material has simple production process, wide application, high performance / cost ratio, no physiological toxicity and many other advantages, and may meet the requirement of coating various solid Chinese medicine preparation.

Description

technical field [0001] The invention relates to a pharmaceutical coating powder and a production process thereof, in particular to a pharmaceutical coating powder containing nanometer materials. technical background [0002] In the prior art, in order to make the solid preparations of medicines (such as tablets, pills, etc.) visually aesthetically pleasing, have better storage stability in preservation, and have better solubility in the gastrointestinal tract, so that it is convenient Taking it, it is often necessary to wrap suitable materials on its surface, which is usually called the coating of the preparation. For many years, domestic pharmaceutical companies, especially the pharmaceutical companies that mainly produce traditional Chinese medicines, have generally used sugar coating. The operation process is complicated and lengthy, and the technology is difficult to master. And the storage stability of the finished product is poor, and the quality is difficult to guara...

AI Technical Summary

Problems solved by technology

[0005] The above-mentioned publications have reported some coating materials and coating compositions. We have learned that many organic substances can be used as film-forming agents for coating materials, such as pyrrolidone polymers, hypromellose, etc., but many pharmaceutical coatings The powder composition still has poor comprehensive physical and chemical parameters; some coating materials and coating compositions reported in some open literature are only set for a single variety, and the applicability is not wide, and the coating performance cannot meet the requirements of the coating of traditional Chinese medicine solid preparations. Complex and changeable application needs, and there is no need to add nano-materials to the composition to make a pharmaceutical coating powder containing nano-materials with superior performance in all aspects and a wide range of applications for the complex properties of traditional Chinese medicine.