External long-acting analgesic

An analgesic, long-acting technology, applied in the field of external medicine, can solve the problems of limited application range and single dosage form, and achieve the effect of no toxic side effects, reasonable formula, safe and reliable use

Inactive Publication Date: 2006-12-20
刘海波
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] The present invention solves the problem that the existing menthol-based medicine has a single dosage form and the scope of use is limited, and provides a new dosage-type analgesic medicine with menthol as the main ingredient-external-use long-acting analgesic

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0012] External long-acting analgesic, comprising menthol and ethanol solution (95%), menthol is 0.5 gram or 3 grams or 6 grams; Menthol is put into container and adds ethanol solution, stirs until menthol fully dissolves, and then Add water for injection until the total amount is 1000ml.

Embodiment 2

[0014] External long-acting analgesics, comprising menthol, ethanol solution (95%) and lidocaine hydrochloride (or procaine), menthol is 0.5 g or 3 g or 6 g, according to the ratio of menthol and lidocaine hydrochloride The ratio is 1: 6 (or 1: 7 or 1: 6.5), and the consumption of corresponding lidocaine hydrochloride can be calculated as 3 grams (or 3.5 grams or 3.25 grams) or 18 grams (or 21 grams or 19.5 grams) or 36 grams (or 42 grams or 39 grams); put the menthol into the container and add ethanol solution, stir until the menthol is fully dissolved, then add lidocaine hydrochloride and a small amount of water for injection and stir to dissolve the lidocaine hydrochloride , and finally add water for injection until the total amount is 1000ml.

Embodiment 3

[0016] Long-acting analgesics for external use, including menthol, ethanol solution (95%), lidocaine hydrochloride (or procaine), glycerin and polysorbate 80, menthol is 1 g or 4 g or 5 g, press mint The ratio of brain to lidocaine hydrochloride, glycerin and polysorbate 80 is 1: 6, 1: 30 and 1: 3 respectively, and the consumption of corresponding lidocaine hydrochloride can be calculated as 6 grams or 24 grams or 30 grams, The consumption of glycerin is 30ml or 120ml or 150ml, the consumption of polysorbate 80 is 3ml or 12ml or 15ml; put menthol into the container and add ethanol solution, stir until menthol is fully dissolved, then add lidocaine hydrochloride, Glycerin and polysorbate 80 are stirred, and finally water for injection is added until the total amount is 1000ml.

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PUM

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Abstract

An externally-applied durable analgetic is proportionally prepared from menthol, alcohol solution, the water for injection, lidocaine hydrochloride, glycerine and polysorbate.

Description

technical field [0001] The invention relates to an external medicine, in particular to an external long-acting analgesic whose main component is menthol. Background technique [0002] At present, the medicament with menthol as the main component has compound lidocaine injection, which is a three-class new drug approved by the Ministry of Health. The indications are limited to anal surgery and postoperative long-acting pain relief, which largely limits the scope of use of the preparation; the formula of compound lidocaine injection is not suitable for external preparations. Contents of the invention [0003] The invention solves the problem that the existing menthol-based medicament has single dosage form and limited application range, and provides a new dosage-type analgesic medicament-external-use long-acting analgesic with menthol as the main component. [0004] The present invention is realized by adopting the following technical scheme: the external long-acting analge...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K31/045A61K31/167A61K9/08A61P29/00
Inventor 刘海波
Owner 刘海波
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