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Use of salivary gland secreta of cyclostomata in preparing medicines

A technology of salivary glands and secretions, applied in the field of pharmaceutical application of salivary gland secretions of Cyclostostomes

Inactive Publication Date: 2007-02-14
LIAONING NORMAL UNIVERSITY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

So far, not used in the pharmaceutical field, especially in anticoagulants and thrombolytics

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0007] Syringes can be used to extract secretions from the middle-black glands below the eyes of Cyclostomes. In order to ensure the activity of the secretions, the secretions are usually stored at low temperature. The secretions can be freeze-dried into powder, or directly stored. in a liquid nitrogen environment. When in use, the salivary gland secretions of Cyclostostomes are taken orally or injected. Under the same conditions, its anticoagulant effect is 20 times that of heparin, and its thrombolytic effect is good.

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PUM

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Abstract

An application of the sialaden secretion of cyclostomata animal in pharmaceutial field is disclosed. As said sialaden secretion is a single-component protein, it can be directly used as medicine. Its advnatages are higher specificity and low toxic by-effect.

Description

Technical field: [0001] The present invention relates to the application of a substance, especially the application of salivary gland secretion of round-stouted animal in pharmacy. Background technique: [0002] At present, the sources of biological natural thrombolytic (dissolving thrombus) agents and anticoagulant (anti-blood coagulation) agents used clinically basically include the following types: one is microorganisms, such as staphylococcal kinase, streptokinase, sodium Soybean kinase etc.; One is invertebrates, such as lumbrokinase, hirudin and tick anticoagulant etc.; There is also a kind of vertebrates closest to the present invention, such as snake venom thrombolytic enzyme etc. Because existing protein molecule thrombolytic agents and anticoagulants have side effects such as bleeding easily, or due to complex components, difficult separation, extraction and purification (snake venom thrombolytic enzyme), or because of differences in dosage and action time, so that...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K35/60A61P7/02
Inventor 李庆伟
Owner LIAONING NORMAL UNIVERSITY